Curriculum Vitae

PERSONAL DETAILS

Associate Professor Dr Aditya Arya


BIOGRAPHY

Dr Aditya Arya is an Associate Professor of Pharmacology and Therapeutics at School of Medicine, Faculty of Health and Medical Sciences, Taylor's University and also Visiting Associate Professor at The University of Melbourne, Australia. Dr Arya obtained PhD in Pharmacology from University of Malaya and appointed as a Senior Lecturer of Pharmacology and Therapeutics at Faculty of Medicine, University of Malaya in the year 2010. He joined Taylor's University, School of Medicine in 2016, he is an active researcher who has published 50 over high impact research papers and has had many leadership roles, including current roles as a project leader of flagship grant under Ageing and Quality of Life, as well as co-researcher with Obesity & Wellbeing program. Moreover, he is involved in several research projects including high impact research grant (HIR) from the Ministry of Higher Education with more than RM 14 million. He is a Research Fellow to the Malaysian Institute of Pharmaceuticals and Nutraceuticals (IPharm) and National Institutes of Biotechnology under the Ministry of Science, Technology & Innovation, Malaysia, since 2015.

His research mainly focus on the cellular and molecular pharmacology in the in vitro and in vivo living system (animal models) to identify specific mechanisms that underlie the development of diabetes and obesity leading to cardiovascular dysfunction linking neuroinflammation. His research group targets insulin networks and role of cytokines in regulating metabolic functions by exploring the translational relevance of signaling pathways and molecular biomarkers involved in the discovery of a candidate/drug as a potential therapeutics.

https://www.thestar.com.my/news/education/2019/02/10/award-from-india-to-scientist/

https://www.connectedtoindia.com/indian-origin-professor-honoured-with-hind-rattan-award-2019-5107.html

ADMINISTRATIVE DUTIES
(Role),(Level),(Duration)
  • Coordinator, Endocrine and Reproductive System Block, School of Medicine, Faculty of Health and Medical Sciences, 01/01/2018 to present
  • Associate Professor, School of Medicine, Faculty of Health & Medical Sciences, 01/02/2016 to present
  • Coordinator, Foundation Block, School of Medicine, Faculty of Health and Medical Sciences, 01/08/2016 to 31/12/2017
ACADEMIC QUALIFICATION
(Qualification),(Institution)
  • PhD in Pharmacology, UNIVERSITY OF MALAYA, Malaysia
  • Master of Pharmacy (Phytopharmacy & Phytomedicine), THE TAMIL NADU DR M.G.R. MEDICAL UNIVERSITY, India
  • Bachelor of Pharmacy, UNIVERSITY OF TECHNOLOGY OF MADHYA PRADESH, India
PROFESSIONAL MEMBERSHIP
(Organisation),(Role),(Duration),(Level)
  • Visiting Associate Professor, University of Melbourne, Australia, Academic , 2018 to 2019 (International)
  • Malaysian Healthy Ageing Society, Member, 2018 to 2019 (National)
AREAS OF EXPERTISE
(Area)
  • Cellular and Molecular Pharmacology (Diabetes, Obesity, Cardio-metabolic, Cancer, Neurological)
  • Clinical Pharmacology and Therapeutics
  • Pharmaco-Toxicology (Drug Discovery, Natural Products, Theranostics)
TEACHING
(Course Title),(Level of Study),(Institution),(Month/Year)
  • Pharmacology and Clinical Therapeutics, Bachelor Degree, Taylor's University (03/2018)
  • Pharmacology and Clinical Therapeutics, Bachelor Degree, Taylor's University (03/2017)
  • Pharmacology and Clinical Therapeutics, Bachelor Degree, Taylor's University (03/2016)
  • Pharmacology and Clinical Therapeutics, Bachelor Degree, University of Malaya (UM) (02/2015)
  • Pharmacology and Clinical Therapeutics, Bachelor Degree, University of Malaya (UM) (02/2014)
  • Pharmacology and Clinical Therapeutics, Bachelor Degree, University of Malaya (UM) (02/2013)
  • Pharmacology and Clinical Therapeutics, Bachelor Degree, University of Malaya (UM) (02/2012)
  • Pharmacology and Clinical Therapeutics , Bachelor Degree, University of Malaya (UM) (02/2011)
  • Pharmacology and Clinical Therapeutics, Bachelor Degree, University of Malaya (UM) (10/2010)
PUBLICATIONS
(Title of publication in APA style)
Article in Journals
2019
  • Chin-Yap Loh, Aditya Arya, Ahmed Fadhil Naema, Won Fen Wong, Gautam Sethi and Chung Yeng Looi. (2019). Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication. doi: 10.3389/fonc.2019.00048. Frontiers in Oncology (ISI-Indexed)
     
2018
  • Abu Sadat Md Sayem, Aditya Arya*, Hamed Karimian, Narendiran Krishnasamy, Ameya Ashok Hasamnis and Chowdhury Faiz Hossain. (2018). Action of Phytochemicals on Insulin Signaling Pathways Accelerating Glucose Transporter (GLUT4) Protein Translocation. Molecules 2018, 23, 258; doi:10.3390/molecules23020258. Molecules (ISI-Indexed)
     
  • Mousa A. Qasem, Mohamed Ibrahim Noordin, Aditya Arya, Abdulsamad Alsalahi and Soher Nagi Jayash. (2018). Evaluation of the glycemic effect of Ceratonia siliqua pods (Carob) on a streptozotocin-nicotinamide induced diabetic rat model. 10.7717/peerj.4788. PeerJ (ISI-Indexed)
     
  • Hairin Taha, Aditya Arya*, Ataul Karim Khan, Nayiar Shahid, Mohammed Ibrahim Bin Noordin, Syam Mohan. (2018). Effect of Pseuduvaria macrophylla in attenuating hyperglycemia mediated oxidative stress and inflammatory response in STZ-nicotinamide induced diabetic rats by upregulating insulin secretion and glucose transporter-1, 2 and 4 proteins expression. doi: 10.1016/j.jab.2018.05.004. Journal of Applied Biomedicine (ISI-Indexed)
     
  • Ali Kadivar, Mohamed Ibrahim Noordin, Aditya Arya*, Behnam Kamalidehghan, Ehsan Taghizadeh Davoudi, Reihaneh Sedghi and Hamid Akbari Javar. (2018). Antiproliferative effects of imatinib mesylate on ZR-75-1 and MDA-MB-231 cell lines via PDGFR-β, PDGF-BB, c-Kit and SCF expression doi.org/10.3892/ijmm.2018.3590. International Journal of Molecular Medicine (ISI-Indexed)
     
  • Sima Kianpur, Aditya Arya* (2018). Mechanism involved in insulin resistance via accumulation of β-amyloid and neurofibrillary tangles: linking type 2 diabetes to Alzheimer’s disease: Drug Design, Development and Therapy. (ISI-Indexed)
     
2017
  • Karimian H., Arya A*., Fadaeinasab M., Razavi M., Hajrezaei M., Khan A.K., Ali H.M., Abdulla M.A., Noordin M.I.(2017). Kelussia odoratissima Mozaff. activates intrinsic pathway of apoptosis in breast cancer cells associated with S phase cell cycle arrest via involvement of P21/p27 in vitro and in vivo. Drug Design, Development and Therapy, 11, pp.337-350 (ISI-Indexed)
     
  • Si Lay Khaing, Siti Zawiah Omar, Aditya Arya, Nooshin Mohebali, Mustafa Ali Mohd (2017). Identification of active extracts of Curcuma zedoaria and their real- time cytotoxic activities on ovarian cancer cells and HUVEC cells. 28 (21): 9182-9187. Biomedical Research (ISI-Indexed)
     
2016
  • Siti Hajar Adam, Nelli Giribabu, Pasupuleti Visweswara Rao, Abu Sadat Md. Sayem, Aditya Arya, Pharkphoom Panichayupakaranant, Praveen Kumar Korla, Naguib Salleh. (2016). Rhinacanthin C ameliorates hyperglycaemia, hyperlipidemia and pancreatic destruction in streptozotocin–nicotinamide induced adult male diabetic rats. doi: /10.1016/j.ejphar.2015.12.028. (ISI-Indexed)
     
  • Siti Hajar Adam, Nelli Giribabu, Normadiah Kassim, Kilari Eswar Kumar, Manuri Brahmayya, Aditya Arya, Naguib Salleh. (2016). Protective effect of aqueous seed extract of Vitis Vinifera against oxidative stress, inflammation and apoptosis in the pancreas of adult male rats with diabetes mellitus. doi: 10.1016/j.biopha.2016.04.032. Biomedicine & Pharmacotherapy (ISI-Indexed)
     
2015
  • Aditya Arya*, Mazen. M. Jamil Al-Obaidi, Rustini Binti Karim, Hairin Taha, Ataul Karim Khan, Nayiar Shahid, Abu Sadat Sayem, Chung Yeng Looi, Mohd Rais Mustafa, Mustafa Ali Mohd, Hapipah Mohd Ali. (2015). Extract of Woodfordia fruticosa flowers ameliorates hyperglycemia, oxidative stress and improves β-cell function in streptozotocin-nicotinamide induced diabetic rat. doi: 10.1016/j.jep.2015.08.057. Journal of Ethnopharmacology (ISI-Indexed)
     
  • Suresh Kumar Ananda Sadagopan, Nooshin Mohebal, Chung Yeng Looi, Mohadeseh Hasanpourghadi, Ashok Kumar Pandurangan, Aditya Arya, Hamed Karimian and Mohd Rais Mustafa.(2015). Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo. SKA Sadagopan, N Mohebali, CY Looi. Journal of Experimental & Clinical Cancer Research (ISI-Indexed)
     
  • Soon Huat Tiong, Chung Yeng Looi, Aditya Arya, Won Fen Wong, Hazrina Hazni, Mohd Rais Mustafa, Khalijah Awang. (2015). Vindogentianine, a hypoglycemic alkaloid from Catharanthus roseus(L.)G.Don (Apocynaceae). doi: 10.1016/j.fitote.2015.01.019. Fitoterapia (ISI-Indexed)
     
  • Fatemeh Hajiaghaalipour, Manizheh Khalilpourfarshbafi, Aditya Arya*. (2015). Modulation of Glucose Transporter Protein by Dietary Flavonoids in Type 2 Diabetes Mellitus. doi: 10.7150/ijbs.11241. International Journal of Biological Sciences (ISI-Indexed)
     
  • Fatemeh Ahmadipour, Mohamed Ibrahim Noordin, Syam Mohan, Aditya Arya, Mohammadjavad Paydar, Chung Yeng Looi, Yeap Swee Keong, Ebrahimi Nigjeh Siyamak, Somayeh Fani, Maryam Firoozi, Chung Lip Yong, Mohamed Aspollah Sukari, Behnam Kamalidehghan. (2015). Koenimbin, a natural dietary compound of Murraya koenigii (L) Spreng: inhibition of MCF7 breast cancer cells and targeting of derived MCF7 breast cancer stem cells (CD44+/CD24-/low): an in vitro study. Drug Design Development and Therapy (ISI-Indexed)
     
  • Hairin Taha, Chung Yeng Looi, Aditya Arya, Won Fen Wong, Lee Fah Yap,Mohadeseh Hasanpourghadi, Mustafa A. Mohd, Ian C Paterson, Hapipah Mohd Ali. (2015). (6E,10E) Isopolycerasoidol and (6E,10E) Isopolycerasoidol Methyl Ester, Prenylated Benzopyran Derivatives from Pseuduvaria monticola Induce Mitochondrial-Mediated Apoptosis in Human Breast Adenocarcinoma Cells. doi:10.1371/journal.pone.0126126. Plos One (ISI-Indexed)
     
2014
  • Hamed Karimian, Soheil Zorofchian Moghadamtousi, Mehran Fadaeinasab, Shahram Golbabapour, Mahboubeh Razavi, Maryam Hajrezaie, Aditya Arya, Mahmood Ameen Abdulla, Syam Mohan, Hapipah Mohd Ali, Mohamad Ibrahim Noordin. (2014). Ferulago angulata activates intrinsic pathway of apoptosis in MCF-7 cells associated with G1 cell cycle arrest via involvement of p21/p27. Drug Design Development and Therapy (ISI-Indexed)
     
  • Mohamed Ibrahim Noordin, Chung Lip Yong, Mofat, Zainuddin, Aditya Arya and Shaik Nyamathulla. (2014). Evaluation of Palm oil-based Paracetamol suppositories by DIfferential Scanning Calorimetry. doi: 13(1);23-29. Tropical Journal of Pharmaceutical Research (ISI-Indexed)
     
  • Abdulwali Ablat, Jamaludin Mohamad, Khalijah Awang, Jamil A. Shilpi and Aditya Arya.(2014).Evaluation of Antidiabetic and Antioxidant Properties of Brucea javanica Seed. doi.org/10.1155/2014/786130. The Scientific World Journal (ISI-Indexed)
     
  • Hairin Taha, Aditya Arya*, Mohammadjavad Paydar, Chung Yeng Looi, Won Fen Wong, Vasudeva Murthy.C.R, M.I. Noordin, Hapipah Mohd. Ali, Mustafa A.M, A.Hamid A.Hadi. (2014). Upregulation of insulin secretion and downregulation of pro-inflammatory cytokines, oxidative stress and hyperglycemia in STZ-nicotinamide-induced type 2 diabetic rats by Pseuduvaria monticola bark extract. doi: 10.1016/j.fct.2014.01.054. Food and Chemical Toxicology (ISI-Indexed)
     
  • Aditya Arya, Al-Obaidi, M. M., Shahid, N., Bin Noordin, M. I., Looi, C. Y., Wong, W. F, Mustafa, M. R. (2014). Synergistic effect of quercetin and quinic acid by alleviating structural degeneration in the liver, kidney and pancreas tissues of STZ-induced diabetic rats: a mechanistic study. doi: 10.1016/j.fct.2014.06.010. Food and Chemical Toxicology (ISI-Indexed)
     
  • Hamed Karimian,Syam Mohan,Soheil Zorofchian Moghadamtousi,Mehran Fadaeinasab, Mahboubeh Razavi, Aditya Arya, Behnam Kamalidehghan, Hapipah Mohd Ali and Mohamad Ibrahim Noordin. (2014). Tanacetum polycephalum (L.) Schultz-Bip. Induces Mitochondrial-Mediated Apoptosis and Inhibits Migration and Invasion in MCF7 Cells. doi:10.3390/molecules19079478. Molecules (ISI-Indexed)
     
2013
  • Chung Yeng Looi, Bushra Moharram, Mohammadjavad Paydar, Yi Li Wong, Kok Hoong Leong, Khalit Mohamad, Aditya Arya, Won Fen Wong and Mohd Rais Mustafa. (2013). Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways. doi:10.1186/1472- 6882-13-166. BMC Complementary and Alternative Medicine (ISI-Indexed)
     
  • Mohammadjavad Paydar, Bushra Abdulkarim Moharam, Yi Li Wong, Chung Yeng Looi, Won Fen Wong, Shaik Nyamathulla, Vijayapandi Pandy, Behnam Kamalidehghan and Aditya Arya*. (2013). Centratherum anthelminticum (L.) Kuntze a potential medicinal plant with pleiotropic pharmacological and biological activities. International Journal of Pharmacology (ISI-Indexed)
     
  • Aditya Arya, Chung Yeng Looi, Won Fen Wong, Mohamed Ibrahim Noordin, Shaik Nyamathulla, Mohd Rais Mustafa and Mustafa Ali Mohd. (2013). In vitro antioxidant, PTP- 1B inhibitory effects and in vivo hypoglycemic potential of selected medicinal plants. doi: 9(1), 50-57. International Journal of Pharmacology (ISI-Indexed)
     
  • Looi, C. Y., Aditya Arya, Cheah, F. K., Muharram, B., Leong, K. H., Mohamad, K, Mustafa, M. R. (2013). Induction of apoptosis in human breast cancer cells via caspase pathway by vernodalin isolated from Centratherum anthelminticum (L.) seeds. doi: 10.1371/journal.pone.0056643. PLoS One (ISI-Indexed)
     
  • Soon Huat Tiong, Chung Yeng Looi, Hazrina Hazni, Aditya Arya, Mohammadjavad Paydar, Won Fen Wong, Shiau-Chuen Cheah, Mohd Rais Mustafa and Khalijah Awang. (2013). Antidiabetic and Antioxidant Properties of Alkaloids from Catharanthus roseus (L.). doi:10.3390/molecules18089770. Molecules (ISI-Indexed)
     
2012
  • Aditya Arya*, Mahmood Ameen Abdullah, B.S Haerian and Mustafa Ali Mohd. (2012). Screening for hypoglycemic activity on the leaf extracts of nine medicinal plants: in-vivo evaluation. E-Journal of Chemistry (ISI-Indexed)
     
  • Ismail Adam Arbab, Chung Yeng Looi, Ahmad Bustamam Abdul, Foo Kit Cheah, Won Fen Wong, Mohd Aspollah Sukari, Rasedee Abdullah, Syam Mohan, Suvitha Syam, Aditya Arya, Manal Mohamed Elhassan Taha, Bushra Muharram, Mohd Rais Mustafa and Siddig Ibrahim Abdelwahab. (2012). Dentatin induces apoptosis in prostate cancer cells via Bcl-2, Bcl-xL, Survivin downregulation, caspase-9, -3/7 activation and NF-?B inhibition. Evidence-Based Complementary and Alternative Medicine (ISI-Indexed)
     
  • Aditya Arya*,Chung Yeng Looi, Shiau Chuen Cheah, Mohd Rais Mustafa and Mustafa Ali Mohd. (2012). Anti-diabetic effects of Centratherum anthelminticum seeds methanolic fraction on pancreatic cells, β-TC6 and its alleviating role in type 2 diabetic rats. Journal of Ethnopharmacology (ISI-Indexed)
     
  • Aditya Arya*, Mouna Achoui, Shiau-Chuen Cheah, Siddig Ibrahim Abdelwahab, Putri Narrima, Syam Mohan, Mohd Rais Mustafa and Mustafa Ali Mohd. (2012). Chloroform fraction of Centratherum anthelminticum (L.) seed inhibits tumor necrosis factor alpha and exhibits pleotropic bioactivities: inhibitory role in human tumor cells. doi:10.1155/2012/627256. Evidence-Based Complementary and Alternative Medicine (ISI-Indexed)
     
  • Aditya Arya*., Cheah, S. C., Looi, C. Y., Taha, H., Mustafa, M. R., & Mohd, M. A. (2012). The methanolic fraction of Centratherum anthelminticum seed downregulates pro-inflammatory cytokines, oxidative stress, and hyperglycemia in STZ-nicotinamide-induced type 2 diabetic rats. doi: 10.1016/j.fct.2012.08.012. Food and Chemical Toxicology (ISI-Indexed)
     
2011
  • Aditya Arya*,Shaik Nyamathulla, Mohamed Ibrahim Noordin,Mustafa Ali Mohd. (2011). Antioxidant and hypoglycemic activities of leaf extracts of three popular Terminalia species. E-Journal of Chemistry (ISI-Indexed)
     
RESEARCH PROJECT
(Project title),(Role),(Duration),(Level)
  • Role of Carvone on multiple mechanism of obesity and cardiac dysfunction in FFAs-treated H9c2 myotubes: in vitro metabolic pathways, Project Leader, 2017 to 2019 (Taylor's University)
  • Role of arjunolic acid and chebulinic acid on cardio-metabolic functioning in MyD88 dependent TLR-4 downstream signaling pathways: Therapeutic and molecular approach, Project Leader, 2017 to 2021 (Taylor's University)
  • Prevention of neurological disorders (Alzheimer's disease) in ageing: A study of synergistic effects of natural plant compounds on the degeneration of -amyloid proteins, Co-researcher, 2017 to 2021 (Taylor's University)
  • Investigation of the role of microbial cell preparation in a clinical trial settings and poly-methoxy flavones as a potential therapeutic agents in the management of obesity, Co-researcher, 2017 to 2022 (Taylor's University)
  • Therapeutic Mechanistic Approach Using Arjunolic, Chebulinic Acid and Polymethoxy Flavones in the Management of Obesity, Co-researcher, 2017 to 2022 (Taylor's University)
  • Attenuating Influenza A Virus Endocytosis By HB-EGF (Heparin-Binding EGF-Like Growth Factor), Co-researcher, 2015 to 2018 (National)
  • A therapeutic intervention with Scutellarin, targeting the high lipogenic diet-induced metabolic heart disease in obese mice, Project Leader, 2014 to 2017 (National)
EVALUATION ACTIVITIES
(Activity),(Duration),(Category)
  • Food Bioscience, 2018 to 2018 (Reviewer)
  • Oxidative Medicine and Cellular Longevity , 2018 to 2018 (Reviewer)
  • Heliyon, 2018 to 2018 (Reviewer)
  • Food Chemistry, 2018 to 2018 (Reviewer)
  • International Journal of Biological Sciences, 2017 to 2018 (Reviewer)
  • Food and Function, 2017 to 2018 (Reviewer)
  • Journal of Applied Biomedicine, 2017 to 2018 (Reviewer)
  • BMC Complementary and Alternative Medicine, 2016 to 2018 (Reviewer)
  • PlosOne, 2016 to 2018 (Reviewer)
  • Biomedicine and Pharmacotherapy, 2015 to 2018 (Reviewer)
  • Food and Chemical Toxicology, 2015 to 2018 (Reviewer)
  • Journal of Ethnopharmacology, 2013 to 2018 (Reviewer)
  • Evidence-Based Complementary and Alternative Medicine, 2013 to 2018 (Reviewer)
SUPERVISION
(Title of Thesis),(Name of Candidates),(Academic Level),(Role)
ONGOING
  • Khurram Aamir, PhD/ Doctoral  (Main Supervisor)
  • Shantini Vijayabalan, PhD/ Doctoral  (Co-supervisor (Internal))
  • Amjad Ayad Qatran, PhD/ Doctoral  (Co-supervisor (Internal))
  • OMAR MOHAMMED AMEN  (Main Supervisor)
  • MD MAHMUDUL HASAN  (Main Supervisor)
  • KHURRAM AAMIR  (Main Supervisor)
  • HIDAYAT ULLAH KHAN  (Main Supervisor)
  • SHANTINI A/P VIJAYABALAN  (Co-supervisor (Internal))
  • AMJAD AYAD QATRAN AL-KHDHAIRAWI  (Co-supervisor (Internal))
PRESENTATION
(Title),(Event),(Date Presented),(Organiser),(Level)
ORAL PRESENTER
  • Diabesity: Phytochemicals Modulates Insulin Signaling and Accelerates Glucose Transporter (GLUT4) Protein, International Conference on Biotherapeutics and Clinical Pharmacology, 01/02/2018 to 02/02/2018, Melbourne, Australia (International)
AWARDS AND STEWARDSHIP
(Name of Award/Stewardship),(Award Category),(Awarding Institution),(Year Awarded),(Type of Award)
  • Hind Rattan Award, Services, NRI Welfare Society of India, New Delhi, 2019 (Hind Rattan Award)
  • Research Fellow, Special, Malaysian Institute of Pharmaceuticals and Nutraceuticals(IPharm), 2015 (Fellowship)
COURSE ATTENDED
(Course Title),(Course Mode),(Date/Duration),(Level)
  • Enabling Anytime Anywhere Teaching through Online Interactive Classroom, Research, 09/06/2017 to 09/06/2017
  • Like Me, Share Me, Play Me, Research, 30/05/2017 to 30/05/2017
  • Academic Lecture by Professor Simon Croft, Research, 16/01/2017 to 16/01/2017