Curriculum Vitae

PERSONAL DETAILS

Associate Professor Dr Looi Chung Yeng


ADMINISTRATIVE DUTIES
(Role),(Level),(Duration)
  • Senior Lecturer I, Faculty of Health & Medical Sciences, 07/08/2017 to present
ACADEMIC QUALIFICATION
(Qualification),(Institution)
  • PhD in Medical Sciences, TOHOKU UNIVERSITY JAPAN, Japan
  • Master of Science (Medical Sciences), TOHOKU UNIVERSITY JAPAN, Japan
  • Bachelor of Science (Hons) Biomedical Sciences, UNIVERSITY PUTRA MALAYSIA, Malaysia
AREAS OF EXPERTISE
(Area)
  • Molecular Pharmacology (Drug design, Drug discovery, Cell therapy, Cancer, Infectious diseases)
RESEARCH INTEREST
(Research Area)
  • Elucidating drug targets and mechanism of action by using cell-line and animal models Evaluation of natural/synthetic compounds for anti-cancer and anti-inflammatory activities Understanding carcinogenesis and immunological disorders using molecular and biochemical analyses Explore novel interventions in cancer and immunological disorders
TEACHING
(Course Title),(Level of Study),(Institution),(Month/Year)
  • Basic Pharmacology and Toxicology with Health Informatics, Bachelor Degree, Taylor's University (03/2021)
  • Advanced Pharmacology, Bachelor Degree, Taylor's University (03/2021)
  • Instrumentation in Medical Diagnostic, Laboratory Science and Blood Banking, Bachelor Degree, Taylor's University (03/2021)
  • Pharmacology, Bachelor Degree, Taylor's University (08/2017)
PUBLICATIONS
(Title of publication in APA style)
Book Chapter
2023
  • Looi, C.Y., Vaisnevee, S. (2023) The role of LncRNA and micro-RNA targeting GLI transcription factors in human cancers, Elsevier. https://shop.elsevier.com/books/transcription-and-translation-in-health-and-disease/garg/978-0-323-99521-4
2017
  • Neama, A. F., Looi, C. Y., Wong W. F. (2017) Lymphocyte Updates-Cancer, Autoimmunity and Infection. http://dx.doi.org/10.5772/intechopen.68869
Article in Journals
2023
  • M.Y. Leong, Y.L. Kong, K. Burgess, W.F. Wong, G. Sethi, C.Y. Looi, (2023). Recent Development of Nanomaterials for Transdermal Drug Delivery. Biomedicines, 11(4):1124, doi: 10.3390/biomedicines11041124. (ISI-Indexed)
  • Tang, T. F., Chan, Y. T., Cheong, H. C., Cheok, Y. Y., Anuar, N. A., Looi, C. Y., Gan, G. G., & Wong, W. F. (2022). Regulatory network of BLIMP1, IRF4, and XBP1 triad in plasmacytic differentiation and multiple myeloma pathogenesis. Cellular immunology, 380, 104594. https://doi.org/10.1016/j.cellimm.2022.104594 (ISI-Indexed)
  • Wong, W. F., Ang, K. P., Sethi, G., & Looi, C. Y. (2023). Recent Advancement of Medical Patch for Transdermal Drug Delivery. Medicina (Kaunas, Lithuania), 59(4), 778. https://doi.org/10.3390/medicina59040778 (ISI-Indexed)
     
  • Chan, Y. T., Cheok, Y. Y., Cheong, H. C., Tang, T. F., Sulaiman, S., Hassan, J., Looi, C. Y., Tan, K. K., AbuBakar, S., & Wong, W. F. (2023). Immune Recognition versus Immune Evasion Systems in Zika Virus Infection. Biomedicines, 11(2), 642. https://doi.org/10.3390/biomedicines11020642 (ISI-Indexed)
  • Muhammad Nooraiman Zufayri Mohd Noor, Adlin Sofea Alauddin, Yin How Wong, Chung Yeng Looi, Eng Hwa Wong, Priya Madhavan, Chai Hong Yeong. (2023). A Systematic Review of Molecular Hydrogen Therapy in Cancer Management. Asian Pacific Journal of Cancer Prevention. Vol 24(1): 37-47. (ISI-Indexed)
  • Sugumar, V., Hayyan, M., Madhavan, P., Wong, W.F., Looi, C.Y. (2023). Current development of chemical penetration enhancers for transdermal insulin delivery. Biomedicines: 11: 664. (ISI-Indexed)
  • Y.L. Kong, M.Y. Harun, M.Y. Leong, C.Y. Looi, W.F. Wong (2023) Interpretation of morphological descriptors on nanocellulose from oil palm frond fibers under weak acid, strong acid, and enzymatic treatments, Materials Today Communications. Volume 37, https://doi.org/10.1016/j.mtcomm.2023.107478 (ISI-Indexed)
2022
  • Cheok, Y.Y.; Tan, G.M.Y.; Lee, C.Y.Q.; Abdullah, S.; Looi, C.Y.; Wong, W.F. (2022) Innate Immunity Crosstalk with Helicobacter pylori: Pattern Recognition Receptors and Cellular Responses. Int. J. Mol. Sci., 23, 7561. https://doi.org/10.3390/ijms23147561 (ISI-Indexed)
  • Sugumar, V., Ang, K. P., Alshanon, A. F., Sethi, G., Yong, P., Looi, C. Y., & Wong, W. F. (2022). A Comprehensive Review of the Evolution of Insulin Development and Its Delivery Method. Pharmaceutics, 14(7), 1406. https://doi.org/10.3390/pharmaceutics14071406 (ISI-Indexed)
  • Ooi YY, Chia AYY, Teoh ML, Lee SH, Tang YQ, Chua LL, Looi CY, Ng WK, Tor YS, Yong PVC. (2022). Redesigning Biomedical Science Practicum towards a New Frontier, International Journal of Information and Education Technology, DOI: 10.18178/IJIET (SCOPUS-Indexed)
  • Cheong, H. C., Cheok, Y. Y., Chan, Y. T., Sulaiman, S., Looi, C. Y., Alshanon, A. F., Hassan, J., Abubakar, S., & Wong, W. F. (2022). Zika Virus Vaccine: The Current State of Affairs and Challenges Posed by Antibody-Dependent Enhancement Reaction. Viral immunology, 35(9), 586–596. https://doi.org/10.1089/vim.2022.0082 (ISI-Indexed)
  • Chan, Y. T., Cheong, H. C., Tang, T. F., Rajasuriar, R., Cheng, K. K., Looi, C. Y., Wong, W. F., & Kamarulzaman, A. (2022). Immune Checkpoint Molecules and Glucose Metabolism in HIV-Induced T Cell Exhaustion. Biomedicines, 10(11), 0. https://doi.org/10.3390/biomedicines10112809 (ISI-Indexed)
  • Tang, T. F., Chan, Y. T., Cheong, H. C., Cheok, Y. Y., Anuar, N. A., Looi, C. Y., Gan, G. G., & Wong, W. F. (2022). Regulatory network of BLIMP1, IRF4, and XBP1 triad in plasmacytic differentiation and multiple myeloma pathogenesis. Cellular immunology, 380, 104594. https://doi.org/10.1016/j.cellimm.2022.104594 (ISI-Indexed)
  • Lee, C. Y. Q., Chan, Y. T., Cheok, Y. Y., Tan, G. M. Y., Tang, T. F., Cheong, H. C., Vadivelu, J., Abdullah, S., Looi, C. Y., & Wong, W. F. (2022). Helicobacter pylori Infection Elicits Type I Interferon Response in Human Monocytes via Toll-Like Receptor 8 Signaling. Journal of immunology research, 2022, 3861518. https://doi.org/10.1155/2022/3861518 (ISI-Indexed)
2021
  • Chai, J.Y., Sugumar, V., Alshawsh, M.A., Wong, W.F., Arya, A., Chong, P.P., Looi, C.Y. The role of smoothened-dependent and-independent hedgehog signaling pathway in tumorigenesis (2021) Biomedicines, 9 (9), art. no. 1188. (ISI-Indexed)
     
  • Cheok YY, Tan GMY, Fernandez KC, Chan YT, Lee CYQ, Cheong HC, Looi CY, Vadivelu J, Abdullah S, Wong WF. Podoplanin Drives Motility of Active Macrophage via Regulating Filamin C During Helicobacter pylori Infection. Front Immunol. 2021 Oct 11;12:702156. doi: 10.3389/fimmu.2021.702156. Erratum in: Front Immunol. 2022 Feb 02;13:857795. PMID: 34707599; PMCID: PMC8543000. (ISI-Indexed)
  • Cheok YY, Lee CYQ, Cheong HC, Vadivelu J, Looi CY, Abdullah S, Wong WF. An Overview of Helicobacter pylori Survival Tactics in the Hostile Human Stomach Environment. Microorganisms. 2021 Dec 3;9(12):2502. doi: 10.3390/microorganisms9122502. PMID: 34946105; PMCID: PMC8705132. (ISI-Indexed)
  • Aamir K, Sugumar V, Khan HU, Looi CY, Juneja R, Waqas M, Arya A. Non-toxic nature of chebulinic acid on biochemical, hematological and histopathological analysis in normal Sprague Dawley rats. Toxicol Res. 2021 Apr 24;38(2):159-174. doi: 10.1007/s43188-021-00092-3. PMID: 35419271; PMCID: PMC8960548. (ISI-Indexed)
  • Chai JY, Sugumar V, Alshanon AF, Wong WF, Fung SY, Looi CY. (2021). Defining the Role of GLI/Hedgehog Signaling in Chemoresistance: Implications in Therapeutic Approaches, Cancers. . 13(19):4746. https://doi.org/10.3390/cancers13194746 (ISI-Indexed)
2020
  • Cheok YY, Lee CYQ, Cheong HC, Looi CY, Wong WF. (2020) Chronic Inflammatory Diseases at Secondary Sites Ensuing Urogenital or Pulmonary Chlamydia Infections. Microorganisms.8(1):127. doi: 10.3390/microorganisms8010127. PMID: 31963395; PMCID: PMC7022716. (ISI-Indexed)
  • Mbous YP, Hayyan M, Wong WF, Hayyan A, Looi CY, Hashim MA. (2020) Simulation of Deep Eutectic Solvents' Interaction with Membranes of Cancer Cells Using COSMO-RS. J Phys Chem B. 124(41):9086-9094. doi: 10.1021/acs.jpcb.0c04801. Epub 2020 Oct 5. PMID: 32930594. (ISI-Indexed)
  • Lee SH, Looi CY, Chong PP, Foo JB, Looi QH, Ng CX, Ibrahim Z.(2020) Comparison of Isolation, Expansion and Cryopreservation Techniques to Produce Stem Cells from Human Exfoliated Deciduous teeth (SHED) with better Regenerative Potential. Curr Stem Cell Res Ther. doi: 10.2174/1574888X15666200928110923. Epub ahead of print. PMID: 32988356. (ISI-Indexed)
2019
  • Loh, C-Y., Arya, A.,Naema, A.F., Wong, WF., Sethi, G., Looi, CY. (2019) Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication. Front. Oncol. | doi: 10.3389/fonc.2019.00048
  • Zainal-Abidin MH, Hayyan M, Ngoh GC, Wong WF, Looi CY. (2019)Emerging frontiers of deep eutectic solvents in drug discovery and drug delivery systems. J Control Release. 316:168-195. doi: 10.1016/j.jconrel.2019.09.019. Epub 2019 Oct 24. PMID: 31669211. (ISI-Indexed)
  • Chong PP, Chin VK, Looi CY, Wong WF, Madhavan P, Yong VC. (2019) The Microbiome and Irritable Bowel Syndrome - A Review on the Pathophysiology, Current Research and Future Therapy. Front Microbiol. doi: 10.3389/fmicb.2019.01136. PMID: 31244784; PMCID: PMC6579922. (ISI-Indexed)
  • Loh CY, Chai JY, Tang TF, Wong WF, Sethi G, Shanmugam MK, Chong PP, Looi CY. (2019) The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges. Cells. 8(10):1118. doi: 10.3390/cells8101118. PMID: 31547193; PMCID: PMC6830116. (ISI-Indexed)
  • Cheong HC, Yap PSX, Chong CW, Cheok YY, Lee CYQ, Tan GMY, Sulaiman S, Hassan J, Sabet NS, Looi CY, Gupta R, Arulanandam B, AbuBakar S, Teh CSJ, Chang LY, Wong WF. (2019) Diversity of endocervical microbiota associated with genital Chlamydia trachomatis infection and infertility among women visiting obstetrics and gynecology clinics in Malaysia. 14(11):e0224658. doi: 10.1371/journal.pone.0224658. PMID: 31738795; PMCID: PMC6860443. (ISI-Indexed)
2018
  • Hematpoor, A., Paydar, M., Liew, S. Y., Sivasothy, Y., Mohebali, N., Looi, C. Y., . . . Awang, K. (2018). Phenylpropanoids isolated from Piper sarmentosum Roxb. induce apoptosis in breast cancer cells through reactive oxygen species and mitochondrial-dependent pathways. Chem Biol Interact, 279, 210-218. doi: 10.1016/j.cbi.2017.11.014 (ISI-Indexed)
  • Siriviriyanun A, Tsai YJ, Voon SH, Kiew SF, Imae T, Kiew LV, Looi CY, Wong WF, Lee HB, Chung LY. (2018). Cyclodextrin- and dendrimer-conjugated graphene oxide as a nanocarrier for the delivery of selected chemotherapeutic and photosensitizing agents, Materials Science and Engineering: C, 89, 307-315. (ISI-Indexed)
  • Laevifins A-G, clerodane diterpenoids from the Bark of Croton oblongus Burm.f. (ISI-Indexed)
  • Chong PP, Chin VK, Wong WF, Madhavan P, Yong VC, Looi CY. (2018) Transcriptomic and Genomic Approaches for Unravelling Candida albicans Biofilm Formation and Drug Resistance-An Update. Genes (Basel). 9(11):540. doi: 10.3390/genes9110540. PMID: 30405082; PMCID: PMC6266447. (ISI-Indexed)
2017
  • Chai, H. J., Kiew, L. V., Chin, Y., Norazit, A., Mohd Noor, S., Lo, Y. L., . . . Chung, L. Y. (2017). Renal targeting potential of a polymeric drug carrier, poly-l-glutamic acid, in normal and diabetic rats. Int J Nanomedicine, 12, 577-591. doi: 10.2147/IJN.S111284 (ISI-Indexed)
  • Hasanpourghadi, M., Looi, C. Y., Pandurangan, A. K., Sethi, G., Wong, W. F., & Mustafa, M. R. (2017). Phytometabolites Targeting the Warburg Effect in Cancer Cells: A Mechanistic Review. Curr Drug Targets, 18(9), 1086-1094. doi: 10.2174/1389450117666160401124842 (ISI-Indexed)
  • Dai, X., Wang, L., Deivasigamni, A., Looi, C. Y., Karthikeyan, C., Trivedi, P., . . . Sethi, G. (2017). A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma. Oncotarget, 8(8), 12831-12842. doi: 10.18632/oncotarget.14606 (ISI-Indexed)
  • Unraveling the cytotoxicity and metabolic pathways of binary natural deep eutectic solvent systems (ISI-Indexed)
  • Applications of deep eutectic solvents in biotechnology and bioengineering-Promises and challenges (ISI-Indexed)
  • Targeting multiple oncogenic pathways for the treatment of hepatocellular carcinoma (ISI-Indexed)
  • Corrigendum: Apoptotic effect of novel Schiff Based CdCl2(C14H21N3O2) complex is mediated via activation of the mitochondrial pathway in colon cancer cells. (ISI-Indexed)
  • Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells (ISI-Indexed)
2016
  • Aydin Tekdas, D., Viswanathan, G., Zehra Topal, S., Looi, C. Y., Wong, W. F., Min Yi Tan, G., . . . Dumoulin, F. (2016). Antimicrobial activity of a quaternized BODIPY against Staphylococcus strains. Org Biomol Chem, 14(9), 2665-2670. doi: 10.1039/c5ob02477c (ISI-Indexed)
  • Hayyan, M., Mbous, Y. P., Looi, C. Y., Wong, W. F., Hayyan, A., Salleh, Z., & Mohd-Ali, O. (2016). Natural deep eutectic solvents: cytotoxic profile. Springerplus, 5(1), 913. doi: 10.1186/s40064-016-2575-9 (ISI-Indexed)
  • Hasanpourghadi, M., Karthikeyan, C., Pandurangan, A. K., Looi, C. Y., Trivedi, P., Kobayashi, K., . . . Mustafa, M. R. (2016). Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell. J Exp Clin Cancer Res, 35, 58. doi: 10.1186/s13046-016-0332-0 (ISI-Indexed)
  • Koosha, S., Alshawsh, M. A., Looi, C. Y., Seyedan, A., & Mohamed, Z. (2016). An Association Map on the Effect of Flavonoids on the Signaling Pathways in Colorectal Cancer. Int J Med Sci, 13(5), 374-385. doi: 10.7150/ijms.14485 (ISI-Indexed)
  • Leong, K. H., Looi, C. Y., Loong, X. M., Cheah, F. K., Supratman, U., Litaudon, M., . . . Awang, K. (2016). Cycloart-24-ene-26-ol-3-one, a New Cycloartane Isolated from Leaves of Aglaia exima Triggers Tumour Necrosis Factor-Receptor 1-Mediated Caspase-Dependent Apoptosis in Colon Cancer Cell Line. PLoS One, 11(4), e0152652. doi: 10.1371/journal.pone.0152652 (ISI-Indexed)
  • Soluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification (ISI-Indexed)
  • Temporal proteomic profiling of Chlamydia trachomatis-infected HeLa-229 human cervical epithelial cells (ISI-Indexed)
  • Acylphenols and dimeric acylphenols from Myristica maxima Warb (ISI-Indexed)
  • Triclosan Demonstrates Synergic Effect with Amphotericin B and Fluconazole and Induces Apoptosis-Like Cell Death in Cryptococcus neoformans (ISI-Indexed)
  • Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds (ISI-Indexed)
  • Erratum: prevalence of plasmid-bearing and plasmid-free chlamydia trachomatis infection among women who visited obstetrics and gynecology clinics in Malaysia (ISI-Indexed)
  • Prevalence of plasmid-bearing and plasmid-free Chlamydia trachomatis infection among women who visited obstetrics and gynecology clinics in Malaysia (ISI-Indexed)
  • Boldine suppresses dextran sulfate sodium-induced mouse experimental colitis: NF-κB and IL-6/STAT3 as potential targets (ISI-Indexed)
2015
  • Ahmadipour, F., Noordin, M. I., Mohan, S., Arya, A., Paydar, M., Looi, C. Y., . . . Kamalidehghan, B. (2015). Koenimbin, a natural dietary compound of Murraya koenigii (L) Spreng: inhibition of MCF7 breast cancer cells and targeting of derived MCF7 breast cancer stem cells (CD44(+)/CD24(-/low)): an in vitro study. Drug Des Devel Ther, 9, 1193-1208. doi: 10.2147/DDDT.S72127 (ISI-Indexed)
  • Ananda Sadagopan, S. K., Mohebali, N., Looi, C. Y., Hasanpourghadi, M., Pandurangan, A. K., Arya, A., . . . Mustafa, M. R. (2015). Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo. J Exp Clin Cancer Res, 34, 147. doi: 10.1186/s13046-015-0266-y (ISI-Indexed)
  • Arya, A., Al-Obaidi, M. M., Karim, R. B., Taha, H., Khan, A. K., Shahid, N., . . . Ali, H. M. (2015). Extract of Woodfordia fruticosa flowers ameliorates hyperglycemia, oxidative stress and improves beta-cell function in streptozotocin-nicotinamide induced diabetic rats. J Ethnopharmacol, 175, 229-240. doi: 10.1016/j.jep.2015.08.057 (ISI-Indexed)
  • Hayyan, M., Looi, C. Y., Hayyan, A., Wong, W. F., & Hashim, M. A. (2015). In Vitro and In Vivo toxicity profiling of ammonium-based deep eutectic solvents. PLoS One, 10(2), e0117934. doi: 10.1371/journal.pone.0117934 (ISI-Indexed)
  • Hajrezaie, M., Paydar, M., Looi, C. Y., Moghadamtousi, S. Z., Hassandarvish, P., Salga, M. S., . . . Abdulla, M. A. (2015). Apoptotic effect of novel Schiff based CdCl(2)(C(1)(4)H(2)(1)N(3)O(2)) complex is mediated via activation of the mitochondrial pathway in colon cancer cells. Sci Rep, 5, 9097. doi: 10.1038/srep09097 (ISI-Indexed)
  • Jamali, H., Paydar, M., Ismail, S., Looi, C. Y., Wong, W. F., Radmehr, B., & Abedini, A. (2015). Prevalence, antimicrobial susceptibility and virulotyping of Listeria species and Listeria monocytogenes isolated from open-air fish markets. BMC Microbiol, 15, 144. doi: 10.1186/s12866-015-0476-7 (ISI-Indexed)
  • Liew, S. Y., Khaw, K. Y., Murugaiyah, V., Looi, C. Y., Wong, Y. L., Mustafa, M. R., . . . Awang, K. (2015). Natural indole butyrylcholinesterase inhibitors from Nauclea officinalis. Phytomedicine, 22(1), 45-48. doi: 10.1016/j.phymed.2014.11.003 (ISI-Indexed)
2014
  • Achoui, M., Heyninck, K., Looi, C. Y., Mustafa, A. M., Haegeman, G., & Mustafa, M. R. (2014). Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs: involvement of MAPK and NF-kappaB pathways. Drug Des Devel Ther, 8, 1993-2007. doi: 10.2147/DDDT.S68659 (ISI-Indexed)
  • Ahmed Hamdi, O. A., Syed Abdul Rahman, S. N., Awang, K., Abdul Wahab, N., Looi, C. Y., Thomas, N. F., & Abd Malek, S. N. (2014). Cytotoxic constituents from the rhizomes of Curcuma zedoaria. ScientificWorldJournal, 2014, 321943. doi: 10.1155/2014/321943 (ISI-Indexed)
  • Hajrezaie, M., Paydar, M., Moghadamtousi, S. Z., Hassandarvish, P., Gwaram, N. S., Zahedifard, M., . . . Abdulla, M. A. (2014). A Schiff base-derived copper (II) complex is a potent inducer of apoptosis in colon cancer cells by activating the intrinsic pathway. ScientificWorldJournal, 2014, 540463. doi: 10.1155/2014/540463 (ISI-Indexed)
  • Faraj, F. L., Zahedifard, M., Paydar, M., Looi, C. Y., Abdul Majid, N., Ali, H. M., . . . Abdulla, M. A. (2014). Synthesis, characterization, and anticancer activity of new quinazoline derivatives against MCF-7 cells. ScientificWorldJournal, 2014, 212096. doi: 10.1155/2014/212096 (ISI-Indexed)
  • Liew, S. Y., Looi, C. Y., Paydar, M., Cheah, F. K., Leong, K. H., Wong, W. F., . . . Awang, K. (2014). Subditine, a new monoterpenoid indole alkaloid from bark of Nauclea subdita (Korth.) Steud. induces apoptosis in human prostate cancer cells. PLoS One, 9(2), e87286. doi: 10.1371/journal.pone.0087286 (ISI-Indexed)
  • Aditya Arya, Al-Obaidi, M. M., Shahid, N., Bin Noordin, M. I., Looi, C. Y., Wong, W. F, Mustafa, M. R. (2014). Synergistic effect of quercetin and quinic acid by alleviating structural degeneration in the liver, kidney and pancreas tissues of STZ-induced diabetic rats: a mechanistic study. doi: 10.1016/j.fct.2014.06.010. Food and Chemical Toxicology (ISI-Indexed)
     
2013
  • Gummadi, V. R., Rajagopalan, S., Looi, C. Y., Paydar, M., Renukappa, G. A., Ainan, B. R., . . . Hosahalli, S. (2013). Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode. Bioorg Med Chem Lett, 23(17), 4911-4918. doi: 10.1016/j.bmcl.2013.06.071 (ISI-Indexed)
  • Looi, C. Y., Aditya Arya, Cheah, F. K., Muharram, B., Leong, K. H., Mohamad, K, Mustafa, M. R. (2013). Induction of apoptosis in human breast cancer cells via caspase pathway by vernodalin isolated from Centratherum anthelminticum (L.) seeds. doi: 10.1371/journal.pone.0056643. PLoS One (ISI-Indexed)
     
2012
  • Arbab, I. A., Looi, C. Y., Abdul, A. B., Cheah, F. K., Wong, W. F., Sukari, M. A., . . . Ibrahim Abdelwahab, S. (2012). Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-kappaB Inhibition. Evid Based Complement Alternat Med, 2012, 856029. doi: 10.1155/2012/856029 (ISI-Indexed)
     
  • Arya, A., Looi, C. Y., Cheah, S. C., Mustafa, M. R., & Mohd, M. A. (2012). Anti-diabetic effects of Centratherum anthelminticum seeds methanolic fraction on pancreatic cells, beta-TC6 and its alleviating role in type 2 diabetic rats. J Ethnopharmacol, 144(1), 22-32. doi: 10.1016/j.jep.2012.08.014 (ISI-Indexed)
  • Aditya Arya*., Cheah, S. C., Looi, C. Y., Taha, H., Mustafa, M. R., & Mohd, M. A. (2012). The methanolic fraction of Centratherum anthelminticum seed downregulates pro-inflammatory cytokines, oxidative stress, and hyperglycemia in STZ-nicotinamide-induced type 2 diabetic rats. doi: 10.1016/j.fct.2012.08.012. Food and Chemical Toxicology (ISI-Indexed)
     
Article in Proceeding
2022
  • Vaisnevee S. Chong CY., Looi CY (2022) Characterization deep eutectic solvents for optimal transdermal drug delivery. 77(3), 42. (SCOPUS-Indexed)
     
RESEARCH PROJECT
(Project title),(Role),(Duration),(Level)
  • Profiling human salivary biomarker(s) panel as a non-invasive detection method for myocardial infarction (MI), Project Leader, 2023 to 2025 (Taylor's University)
  • Selective isolation method, characterization, and functionalization of nanocrystalline cellulose from oil palm frond fiber (OPFF) with antimicrobial activities, Co-researcher, 2021 to 2024 (National)
  • Investigating anticancer activity of anti-MIRNA 21, MIR-145 mimics and Doxorubicin Cocktail packaged in nanoparticles conjugated with A6 Tumour-homing peptide for targeted inhibition of triple-negative breast cancer , Co-researcher, 2020 to 2024 (National)
  • Elucidating the molecular target and the role of choline-geranic acid (CAGE) deep eutectic solvent in transdermal insulin delivery, Project Leader, 2020 to 2023 (National)
  • Copper as target for colorectal cancer therapeutics: Anti-cancer effect of copper (II) complex derived from S-benzyldithiocarbazate and 3-acetylcoumarin, Co-researcher, 2018 to 2019 (Taylor's University)
  • The role of RUNX3 and E-cadherin underlying epithelial to mesenchymal (EMT)-associated cellular plasticity in gastric cancer, Project Leader, 2018 to 2019 (Taylor's University)
  • Immunomodulatory and anti-inflammatory effects of Tualang and Kelulut honeys on activated microglial cells, Co-researcher, 2017 to 2019 (Taylor's University)
EVALUATION ACTIVITIES
(Activity),(Duration),(Category)
  • Review Editor in Frontiers in Immunology, 2021 to 2023 (Article in Journal)
  • Review Editor in Cancer Treatment and Research Communications, 2021 to 2023 (Article in Journal)
  • Review Editor for Translational Oncology, 2021 to 2023 (Article in Journal)
  • Associate Editor for the BMC Complementary and Therapies journal. , 2018 to 2023 (Article in Journal)
SUPERVISION
(Title of Thesis),(Name of Candidates),(Academic Level),(Role)
ONGOING
  • ROMEL MARIO SOYZA  (Main Supervisor)
  • ROMEL MARIO SOYZA  (Co-supervisor (Internal))
  • VAISNEVEE A/P SUGUMAR  (Main Supervisor)
  • LEONG MOONG YAN  (Co-supervisor (Internal))
  • MAHMOUD VALIZADEH LAKEH  (Main Supervisor)
  • MAHMOUD VALIZADEH LAKEH  (Main Supervisor)
  • MAHMOUD VALIZADEH LAKEH  (Main Supervisor)
  • ANG KUAN PING  (Main Supervisor)
  • NAGULAN A/L SINNAIH  (Co-supervisor (Internal))
  • MASA NAZIYAH SHABAN  (Main Supervisor)
COMPLETED
  • IN VITRO STUDY ON THE ROLE OF HEDGEHOG SIGNALING PATHWAY IN CELL CYCLE REGULATION, CELL MIGRATION, AND CHEMORESISTANCE IN GASTRIC CANCER, LOH CHIN YAP  (Main Supervisor)
  • DEVELOPMENT OF A TISSUE MICROARRAY FOR MOLECULAR PROFILING OF MALAYSIAN COLORECTAL CANCER BY IMMUNOHISTOCHEMISTRY, SEE WEE HAN  (Main Supervisor)
  • IN-VITRO STUDY ON THE ROLE OF CANONICAL SONIC HEDGEHOG SIGNALING IN GASTRIC CANCER AGS AND MKN45 AND HUMAN EMBRYONIC KIDNEY 293T CELL LINES, CHAI JIAN YI  (Main Supervisor)
  • EVALUATION ON THE EFFECT OF CHEBULINIC ACID IN PANCREAS AND HEART OF STREPTOZOTOCIN (STZ)-NICOTINAMIDE INDUCED DIABETIC RATS., VAISNEVEE A/P SUGUMAR  (Main Supervisor)
ENDOWMENT/GIFT & DONATION
(Contribution Details),(Donor/Contributor),(Type),(Category)
  • Sponsorship for Community Service Project , Mah Sing Foundation, Money (Donation)
AWARDS AND STEWARDSHIP
(Name of Award/Stewardship),(Award Category),(Awarding Institution),(Year Awarded),(Type of Award)
  • International University Carnival on E-Learning (IUCEL) 2023, Competition, Universiti Malaysia Pahang Al-Sultan Abdullah, 2023 (Bronze)
  • Silver award, Exhibition/Invention, Malaysian Invention and Design Society (MINDS), 2023 (Collaborator)
  • Anugerah Khas Menteri Pengajian Tinggi: Rekabentuk Kurikulum Dan Penyampaian Inovatif (AKRI) 2022, Competition, Kementerian Pendidikan Malaysia, 2022 , Education, Ministry of Higher Education, 2022 (Contributor)
  • Silver Medal in the poster competition for poster entitled Redesigning Biomedical Science Practicum Towards A New Frontier . 2021 edition of International University Carnival on E-Learning (IUCEL 2021): "Leading Innovation Towards Digitalized Community", 15 16 June 202, Education, Universiti Utara Malaysia (UUM), 2021 (Contributor)
  • Silver Medal in the oral competition entitled Redesigning Biomedical Science Practicum Towards A New Frontier . MEI2021 4th International Conference on Medical Education Informatics, Competition, University of Nottingham, Nottingham, UK, 2021 (Best Oral)
CONTRIBUTION TO SOCIETY
(Contribution to Society),(Duration),(Level)
  • Taylor's University collaborated with Mah Sing Foundation, Breast Cancer Welfare Association Malaysia (BCWA) and Community-at-Heart (NGO) to run a Community Health Check and Awareness for the resident of Pangsapuri Enggang. , 19/06/2022 (Community)