Curriculum Vitae

PERSONAL DETAILS

Dr Jason Loo Siau Ee


BIOGRAPHY

I graduated with an MPharm from the University of Strathclyde and obtained my PhD (Medicinal Chemistry) from the University of Nottingham before joining Taylor's University School of Pharmacy in 2015. I am also a Board Certified Pharmacotherapy Specialist (BCPS). I currently teach and lead several modules in Clinical Pharmacy and Pharmaceutical Chemistry, and am also the Student Adviser for the Taylor's University Pharmacy Student Society (TUPSS), which aims to develop student leaders through various events and activities in collaboration with pharmaceutical industry partners and NGOs. I was also previously Associate Dean (International Relations), during which I coordinated international relations and develops student exchange programs with partner universities in Australia, UK, Thailand, and Indonesia. 

My research areas are mainly focused on computational chemistry and molecular modelling of G protein-coupled receptors for structure-based drug design, including homology modelling, molecular dynamics simulations, virtual screening, and free energy calculations. Other research interests include aspects of pharmacy practice and pharmacy education. I have been an invited speaker for several CPD workshops for pharmacists, and continue to engage with the profession.

ADMINISTRATIVE DUTIES
(Role),(Level),(Duration)
  • International Affairs Committee, School of Pharmacy, Faculty of Health & Medical Sciences, 01/04/2017 to present
  • Student Advisor, Faculty of Health & Medical Sciences, 01/08/2015 to present
  • Lecturer I, Faculty of Health & Medical Sciences, 23/03/2015 to present
  • Associate Dean (International Relations), Faculty of Health & Medical Sciences, 01/08/2016 to 01/04/2017
ACADEMIC QUALIFICATION
(Qualification),(Institution)
  • Doctor of Philosophy, THE UNIVERSITY OF NOTTINGHAM, -
  • Master of Pharmacy, UNIVERSITY OF STRATHCLYDE GLASGOW, -
PROFESSIONAL MEMBERSHIP
(Organisation),(Role),(Duration),(Level)
  • Board of Pharmacy Specialties, Board Certified Pharmacotherapy Specialist, 2018 to present (International)
  • Malaysian Pharmaceutical Society (MPS), Life member, Since 2016 (National)
AREAS OF EXPERTISE
(Area)
  • Medicinal Chemistry
  • Drug Discovery
  • Computational Chemistry
PUBLICATIONS
(Title of publication in APA style)
Article in Journals
2019
  • Loo JSE, Emtage AL, Murali L, Lee SS, Kueh ALW, Alexander SPH. Ligand discrimination during virtual screening of the CB1 cannabinoid receptor crystal structures following cross-docking and microsecond molecular dynamics simulations. RSC Advances. 2019; 9; 15949 - 15956 (ISI-Indexed)
  • Yau MQ, Emtage AL, Chan NJY, Doughty SW, Loo JSE. Evaluating the performance of MM/PBSA for binding affinity prediction using Class A GPCR crystal structures. J. Comput. Aided Mol. Des. 2019; 33(5), 487-496 (ISI-Indexed)
  • Foo JB, Ng LS, Lim JH, Tan PX, Lor YZ, Loo JSE, Low ML, Chan LC, Beh CY, Leong SW, Saiful Yazan L, Tor YS, How CW. Induction of Cell Cycle Arrest and Apoptosis by Copper Complex Cu(SBCM)2 Towards Oestrogen-Receptor Positive MCF-7 Breast Cancer Cells. RSC Adv. 2019; 9(32), 18359-18370 (ISI-Indexed)
  • Foong RTK, Sellappans R, Loo JSE. Awareness of Beers Criteria and knowledge of potentially inappropriate medications among community pharmacists in Malaysia. J. Eval. Clin. Pract. 2019
  • Loo JSE, Lo EMY, Mai CW, Gan PW, Lee EL, Tiong JJL. Separation of prescribing and dispensing in malaysia: Public perception on pharmacists’ roles and agreement towards a separation policy. J. Pharm. Pract. Res. 2019 (In Press)
2018
  • Loo JSE, Loh MH, Tiong JJL. Utilization of Community Pharmacy Dispensing Services in the Absence of Dispensing Separation: An Evaluation of Prescriptions Dispensed. Indian J. Pharm. Sci., 2018;80.2;390-395 (ISI-Indexed)
  • Loo JSE, Emtage AL, Ng KW, Yong ASJ, Doughty SW. Assessing GPCR homology models constructed from templates of various transmembrane sequence identities: Binding mode prediction and docking enrichment , J. Mol. Graph. Model. 2018 ;80 ; 38-47 (ISI-Indexed)
2017
  • Loo JSE, Lim SW, Ng YK, Tiong JJ. Pharmacy Students in Private Institutions of Higher Education: Motivating Factors When Studying Pharmacy and Influences on University Choice. Int J Pharm Prac 2017. (SCOPUS-Indexed)
2016
  • Tiong J.J.L., Loo J.S.E., Mai C.-W. (2016). Global antimicrobial stewardship: A closer look at the formidable implementation challenges. Frontiers in Microbiology, 7(NOV), pp.- (ISI-Indexed)
Article in Proceeding
2018
  • Yau M, Emtage A and Loo JS (2018). Evaluating the Performance of MM/PBSA for Binding Affinity Prediction Using G Protein-Coupled Receptor Crystal Structures. Front. Pharmacol. Conference Abstract: International Conference on Drug Discovery and Translational Medicine 2018 (ICDDTM '18) “Seizing Opportunities and Addressing Challenges of Precision Medicine”. doi: 10.3389/conf.fphar.2018.63.00052 (ISI-Indexed)
2017
  • Ng KW, Loo JSE. Evaluating the ability of unbiased molecular dynamics simulations to refine homology models of GPCRs: A case study using the adenosine A2A receptor. The 2nd International Conference on Pharmacy Education and Research Network of ASEAN; 2017 November 21-22, Kuala Lumpur, Malaysia.
  • Loo JSE, Emtage AL, Ng KW, Yong ASJ, Doughty SW. An assessment of G protein-coupled receptor homology models constructed from templates of various transmembrane sequence identities. 13th Malaysian Pharmaceutical Society Scientific Conference; Malaysian Journal of Pharmacy 2017; 3(1);17
Print Media
2018
  • Loo JSE. Common yet overlooked: Non-alcoholic fatty liver disease. MIMS Pharmacy Malaysia. May 2018; 22-28
2016
  • Loo JSE. Management of Insomnia: Making sense of hypnotic choices. MIMS Pharmacy Malaysia. April 2016; 9-11.
RESEARCH PROJECT
(Project title),(Role),(Duration),(Level)
  • Application of MM/PBSA-based methods for the identification of novel leads targeting GPCRs implicated in ageing-related diseases, Project Leader, 2017 to 2021 (Taylor's University)
SUPERVISION
(Title of Thesis),(Name of Candidates),(Academic Level),(Role)
ONGOING
  • YAU MEI QIAN  (Main Supervisor)
  • YAU MEI QIAN  (Main Supervisor)
PRESENTATION
(Title),(Event),(Date Presented),(Organiser),(Level)
ORAL PRESENTER
  • Microsecond molecular dynamics simulations of the active and inactive-state CB1 cannabinoid receptor following cross-docking: Agonist/antagonist discrimination in virtual screening., 2nd International Symposium on Bioinformatics, 20/12/2018 to 21/12/2018, Perdana University, MyBioInfoNet, APBioNet (International)
  • An Assessment of G Protein-Coupled Receptor Homology Models Constructed from Templates of Various Transmembrane Sequence Identities, 13th MPS Scientific Conference, 04/11/2017 to 05/11/2017, Universiti Sains Malaysia Malaysian Pharmaceutical Society (National)
POSTER PRESENTER
  • Evaluating the Performance of MM/PBSA for Binding Affinity Prediction Using G Protein-Coupled Receptor Crystal Structures, International Conference on Drug Discovery and Translational Medicine 2018, 04/12/2018 to 05/12/2018, Malaysian Association for Cancer Research (International)
  • Evaluating the ability of unbiased molecular dynamics simulations to refine homology models of GPCRs: A case study using the adenosine A2A receptor, The 2nd International Conference On Pharmacy Education and Research Network of ASEAN (ASEAN PharmNET 2017), 21/11/2017 to 22/11/2017, Universiti Kebangsaan Malaysia Taylor's University Universiti Teknologi MARA (International)
CONTRIBUTION TO SOCIETY
(Contribution to Society),(Duration),(Level)
  • CSR Health Screening with Pfizer Sdn Bhd - Organizing Committee, 28/10/2017 to 28/10/2017 (Community)
  • TUPSS Public Health Campaign 2017 with Bayer & Watsons - Adviser, 25/04/2017 to 25/04/2017 (University)
  • CSR Health Screening at PPR Sri Pantai with Pfizer Sdn Bhd - Organizing Committee, 08/10/2016 to 08/10/2016 (Community)
  • TUPSS Public Health Campaign 2015 with Pfizer Sdn Bhd and Ministry of Health - Adviser, 10/05/2016 to 10/05/2016 (University)
  • Joint Health Outreach Program (Faculty of Health and Medical Sciences) -Organizing Committee, 03/10/2015 to 03/10/2015 (Community)
COURSE ATTENDED
(Course Title),(Course Mode),(Date/Duration),(Level)
  • SoP Curriculum Review Workshop (Day 2), Research, 28/02/2017 to 28/02/2017
  • SoP Curriculum Review Workshop (Day 1), Research, 24/02/2017 to 24/02/2017
  • SOP eLearning Sharing Session, Research, 14/02/2017 to 14/02/2017
  • Workshop for Curriculum Review 01 (SoP only), Research, 13/02/2017 to 13/02/2017
  • Introduction to Board of Pharmacy Specialties (BPS) Certification, Research, 06/02/2017 to 06/02/2017