Curriculum Vitae

PERSONAL DETAILS
ADMINISTRATIVE DUTIES
(Role),(Level),(Duration)
  • Coordinator -Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health and Medical Sciences, 01/01/2021 to present
  • Member- Student Selection Committee, School of Pharmacy, 01/03/2019 to present
  • Member-School Board of Examiners, School of Pharmacy, 01/02/2017 to present
  • Member-School Programme Committee, School of Pharmacy, 01/02/2017 to present
  • Member-Industry Advisory Panel UG and PG Programmes, School of Pharmacy, 01/02/2017 to present
  • Stream coordinator-Pharmaceutical Chemistry , School of Pharmacy, Faculty of Health and Medical Sciences., 01/02/2017 to 31/12/2020
  • Member-Academic Staff Steering Committee, School of Pharmacy, Faculty of Health and Medical Sciences, Taylor's University., 01/09/2016 to 31/08/2017
  • Member-Academic Staff Steering Committee, School of Pharmacy, Faculty of Health and Medical Sciences, Taylor's University., 01/05/2015 to 30/04/2016
ACADEMIC QUALIFICATION
(Qualification),(Institution)
  • Doctor of Philosophy, UNIVERSITY OF SAINS MALAYSIA, Malaysia
AREAS OF EXPERTISE
(Area)
  • Medicinal Chemistry (MEDICINAL CHEMISTRY-Synthesis of small molecules suitable as antibacterial and anticancer agents; PHYTOCHEMISTRY- Extraction, standardization, and isolation of phytoconstituents from plants; In vivo Acute toxicity studies and Pharmacokinetics studies.)
TEACHING
(Course Title),(Level of Study),(Institution),(Month/Year)
  • Pharmaceutical Organic Chemistry, Bachelor Degree, Taylor's University (04/2024)
  • Pharmaceutical Analysis , Bachelor Degree, Taylor's University (04/2024)
  • Advanced Drug Design and Discovery , Bachelor Degree, Taylor's University (04/2024)
  • Principles of Pharmaceutical chemistry, Bachelor Degree, Taylor's University (09/2024)
  • Drug Design and Biotechnology , Bachelor Degree, Taylor's University (09/2024)
PUBLICATIONS
(Title of publication in APA style)
Article in Journals
2024
  • Yanan Wang., Chai‑Yee Chin., Naveen Kumar Hawala Shivashekaregowda., Qin Shi.(2024).Implications of Low‑concentration Polymer on the Physical Stability of Glassy Griseofulvin: Role of the Segmental Mobility. AAPS PharmSciTech, 25:103, 1-9. (ISI-Indexed)
     
  • Yanan Wang., Chai-Yee Chin., Naveen Kumar Hawala Shivashekaregowda.,Qin Shi. (2024). Effects of polyvinylpyrrolidone on the crystallization of amorphous griseofulvin: fracture and molecular mobility.Applied Crystallography. 57, 1-11. (ISI-Indexed)
     
  • Ang, J-J., Shivashekaregowda, N.K.H., Yow, H-Y., Rizwan, F., Wong, P-F., Jantan, I., Omar M.H., Misnan, N.M., Low, B-S. (2024) Stimulatory Effect of Eurycomanone from Eurycoma longifolia Jack roots on Dopamine Secretion in Human Neuroblastoma SH-SY5Y Cell Line. Natural Product Research. (SCOPUS-Indexed)
2023
  • Muttiah Barathan, Naveen Kumar Hawala Shivashekaregowda, See Mee Hoong, Kumutha Malar Vellasamy, Jamuna Vadivelu (2023).Anticancer effect of aromatic isoniazid derivatives in human gastric adenocarcinoma cells. Toxicology and Applied Pharmacology.481, 116767. (ISI-Indexed)
     
  • Matthew James Cheesman, Naveen Kumar Hawala Shivashekaregowda, Ian Edwin Cock (2023).Bacterial Foodborne Illness in Malaysia: Terminalia spp. as a Potential Resource for Treating Infections and Countering Antibiotic Resistance. Malays J Med Sci.30(2):42–54. (SCOPUS-Indexed)
     
2022
  • Wan Yean Chung, Nusaibah Abdul Rahim, Mohd Hafidz Mahamad Maifiah, Naveen Kumar Hawala Shivashekaregowda, Yan Zhu, Eng Hwa Wong,.(2022) .In-silico genome-scale metabolic modeling and in-vitro static time-kill studies of exogenous metabolites alone and with polymyxin B against Klebsiella pneumoniae. Frontiers in Pharmacology.13, 1-10 (ISI-Indexed)
     
  • Zhi Xin Phuna, Bibhu Prasad Panda, Naveen Kumar Hawala Shivashekaregowda, Priya Madhavan. (2022).Recent development in nanocrystal based drug delivery for neurodegenerative diseases: Scope, challenges, current and future prospects (ISI-Indexed)
     
  • Zhi Xin Phuna, Bibhu Prasad Panda, Naveen Kumar Hawala Shivashekaregowda and Priya Madhavan*. Nanoprotection from SARS-CoV-2: Would Nanotechnology Help in Personal Protection Equipment (PPE) to Control the Transmission of COVID-19? Journal of Environmental Health Research. (ISI-Indexed)
  • Wan Yean Chung, Yan Zhu, Mohd Hafidz Mahamad Maifiah, Naveen Kumar Hawala Shivashekaregowda, Eng Hwa Wong, Nusaibah Abdul Rahim. Exogenous metabolite feeding on altering antibiotic susceptibility in Gram-negative bacteria through metabolic modulation: a review. Metabolomics (2022) 18:47 (SCOPUS-Indexed)
     
2021
  • Wan Yean Chung, Yan Zhu, Mohd Hafidz Mahamad Maifiah, Naveen Kumar Hawala Shivashekaregowda, Eng Hwa Wong*, Nusaibah Abdul Rahim*.Novel antimicrobial development using genome-scale metabolic model of Gram-negative pathogens: A review. The Journal of Antibiotics. 74(2):95-104. (ISI-Indexed)
  • Fernandez, M., Shivashekaregowda, N.K. & Yin, Y.H. (2021). The potential role of genus Tinospora in wound healing: a review. International Journal of Pharmacy and Pharmaceutical Sciences, 13(4), 21-29.
     
  • MUTTIAH BARATHAN, AHMAD KHUSAIRY ZULPA, KUMUTHA MALAR VELLASAMY, VANITHA MARIAPPAN, NAVEEN KUMAR HAWALA SHIVASHEKAREGOWDA, ZARIDATUL AINI IBRAHIM and JAMUNA VADIVELU (2021).Cytotoxic Activity of Isoniazid Derivative in Human Breast Cancer Cells. in vivo 35: 2675-2685. (ISI-Indexed)
      
2019
  • Sriramaneni RN, Sadikun A, Shivashekaregowda NK, Venkatappa A, Asmawi MZ (2019). Identification of bioactive diterpenoid lactones using nuclear magnetic resonance from Andrographis paniculata. Pharmacognosy Research 2019;11:121-6 (SCOPUS-Indexed)
  • Krishnamoorthy R, Panda BP , Shivashekaregowda NKH, Low BS, Bhattamisra SK (2019).Gliclazide loaded PLGA-HPMC second generation nanocrystals for oral delivery: Design, development and in vitro performance characterization.Malaysian Journal of Medicine and Health Sciences.15(2), 44. (SCOPUS-Indexed)
     
  • Malarvili, M.W, Bibhu Prasad P, Bin Seng L, Naveen Kumar, H.S.(2019).Effect of extraction temperature on polyphenolic content and antioxidant potential of Gynura crepioides leaves.Malaysian Journal of Medicine and Health Sciences Vol.15 Supp 2, 10. (ISI-Indexed)
  • Bibhu Prasad P., Rachna Krishnamoorthy., Subrat Kumar B., Naveen Kumar HS. , Low Bin Seng., Sujata Patnaik (2019).Fabrication of Second Generation Smarter PLGA Based Nanocrystal Carriers for Improvement of Drug Delivery and Therapeutic Efficacy of Gliclazide in Type-2 Diabetes Rat Model. Sci Rep 9, 17331. (ISI-Indexed)
     
2018
  • Bibhu Prasad Panda , Rachna Krishnamoorthy, Naveen Kumar Hawala Shivashekaregowda, Sujata Patnaik (2018). Influence of Poloxamer 188 on Design and Development of Second Generation PLGA Nanocrystals of Metformin Hydrochloride. Nano Biomedicine and Engineering, 10(4), 334-343. (SCOPUS-Indexed)
     
2015
  • Kumarappan C., Srinivasan R., Jeevathayaparan S., Rajinikanth R., Naveen Kumar H.S., Senthilrajan S., Subhash C.M. (2015). Ichnocarpus frutescens: A valuable medicinal plant. Pharmacologyonline 2, pp.18-37 (SCOPUS-Indexed)
     
2014
  • Naveen Kumar H S, Parumasivam, T, Pazilah Ibrahim, Mohd. Zaini Asmawi, Amirin Sadikun (2014) Synthesis of hydrophobic N-acylated isonicotinic acid hydrazide derivatives as potential enoyl-acyl carrier protein reductase (InhA) inhibitors. Medicinal Chemistry Research, 23(3), 1267-1277. (ISI-Indexed)
     
  • Naveen Kumar, H S, Paramashivam, T, Fatimah Jumaat, Pazilah Ibrahim, Mohd. Zaini Asmawi, Amirin Sadikun (2014) Synthesis and evaluation of isonicotinoyl hydrazone derivatives as antimycobacterial and anticancer agents. Medicinal Chemistry Research, 23(1), 269-279. (ISI-Indexed)
     
2013
  • Parumasivam, T, Naveen Kumar, H S, Ibrahim, P, Sadikun, A and Mohamad, S (2013) Anti-tuberculosis activity of lipophilic isoniazid derivatives and their interactions with first-line anti-tuberculosis drugs. Journal of Pharmacy Research, 7, 313-317. (SCOPUS-Indexed)
     
  • Thaigarajan Parumasivam, Naveen Kumar H S, Pazilah Ibrahim, Amirin Sadikun, and Suriyati Mohamad (2013). Effects of a lipophilic isoniazid derivative on the growth and cellular morphogenesis of Mycobacterium tuberculosis H37Rv. International Journal of Pharmacy and Pharmaceutical Sciences, 5 (4), 43-50.
     
2010
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Jia Hao Goh and Hoong-Kun Fun (2010) (E)-N’-(2, 3, 4-Trihydroxybenzylidene)isonicotinohydrazide dihydrate. Acta Crystallogr Sec E-Struct Rep Online, E66, part 11, o3017–o3018. (SCOPUS-Indexed)
     
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Madhukar Hemamalini and Hoong-Kun Fun (2010) (E)-N’-(2-Benzyloxybenzylidene)isonicotinohydrazide methanol solvate monohydrate. Acta Crystallogr Sec E-Struct Rep Online , E66, part 7, o1337–o1338. (SCOPUS-Indexed)
     
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Chin Sing Yeap and Hoong-KunFun(2010)Bis{(E)-N’-[2,4-Bis(trifluromethyl)-benzylidene]isonicotin ohydrazide} monohydrate. Acta Crystallogr Sec E-Struct Rep Online, E66, part 8, o1918-o1919. (SCOPUS-Indexed)
     
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Chin Sing Yeap and Hoong-KunFun(2010)(E)-N’-[(E)-3-(4-Hydroxy-3-methoxy phenyl ) allylidene ]isonico- tino hydrazide. Acta Crystallogr Sec E-Struct Rep Online, E66, part 2, o291. (SCOPUS-Indexed)
     
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Wan-Sin Loh and Hoong-Kun Fun (2010) (E )-N’-[(E)-2-Methylpent-2-enylidene]isonicotinohydrazide. Acta Crystallogr Sec E-Struct Rep Online, E66, part 7, o1489–o1490. (SCOPUS-Indexed)
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Chin Sing Yeap and Hoong-KunFun (2010) (E)-N’-(2,4,5-Triflurobenzylidene)isonicotinohydrazide monohydrate. Acta Crystallogr Sec E-Struct Rep Online, E66, part 3, o579. (SCOPUS-Indexed)
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Wan-Sin Loh and Hoong-KunFun(2010)(E)-N-(2,4,6-Trihydroxybenzylidene)isonicotinohydrazide sesqui hydrate. Acta Crystallogr Sec E-Struct Rep Online, E66, part 5, o1202–o1203. (SCOPUS-Indexed)
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Jia Hao Goh and Hoong-Kun Fun (2010) (E)-N’-(2,4,6-Trimethylbenzylidene)isonicotinohydrazide. Acta Crystallogr Sec E-Struct Rep Online, E66, part 7, o1493. (SCOPUS-Indexed)
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Chin Sing Yeap and Hoong-Kun Fun (2010) (E)-N'-(2,3,4-trimethoxybenzylidene)isonicotinohydrazide. Acta Crystallogr Sec E-Struct Rep Online, E66, part 5, o1231–o1232. (SCOPUS-Indexed)
     
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Chin Sing Yeap and Hoong-KunFun (2010) (E)-N'-(2,4,5-Trimethoxybenzylidene)isonicotinohydrazide dihydrate. Acta Crystallogr Sec E-Struct Rep Online , E66, part 5, o1235–o1236. (SCOPUS-Indexed)
     
2009
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Jia Hao Goh and Hoong-Kun Fun (2009)N'-[(3-Methyl-2-thienyl)carbonyl]isonicotinohydrazide. Acta Crystallogr Sec E-Struct Rep Online, E65, part 9, o2235–o2236. (SCOPUS-Indexed)
     
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Chin Sing Yeap and Hoong-Kun Fun (2009) N’-(Cyclohexanecarbonyl)isonicotinohydrazide. Acta Crystallogr Sec E-Struct Rep Online, E65, part 8, o1912. (SCOPUS-Indexed)
     
  • Naveen Kumar H S, Amirin Sadikun, Pazilah Ibrahim, Wan-Sin Loh and Hoong-Kun Fun(2009)(E)-N’-(3-Benzyloxy-4-methoxybenzylidene) isonicotinohydrazide. Acta Crystallogr Sec E-Struct Rep Online, E65, part 10, o2540–o2541. (SCOPUS-Indexed)
     
Article in Proceeding
2018
  • Asian Journal of Pharmaceutical and Clinical Research (SCOPUS-Indexed)
2017
  • Stephanie S, Naveen Kumar H.S, Philip K, Wayah SB, Panda B.P, Low B.S.(2017). Gynura crepioides leaves extract: An antibacterial study. 3(1) 35.
RESEARCH PROJECT
(Project title),(Role),(Duration),(Level)
  • Innovative Silver Nanoparticles Encapsulated with Phytochemicals for Targeting Candida glabrata Biofilm: Unravelling Its Modulatory Effects on Gene Expression, Host Oxidative Response and Antimicrobial Defense, Co-researcher, 2021 to 2025 (National)
  • Innovative Silver Nanoparticles Encapsulated with Phytochemicals for Targeting Candida glabrata Biofilm: Unravelling Its Modulatory Effects on Gene Expression, Host Oxidative Response and Antimicrobial Defense, Co-researcher, 2021 to 2024 (National)
  • A transcriptomic study of bioactive compounds isolated from bioactivity-guided fractionation of Eurycoma longifolia Jack on dopaminergic SH-SY5Y neuronal cell-line , Co-researcher, 2021 to 2024 (National)
  • Synergistic antibacterial activity of novel exogenous metabolite-polymyxin combinations against Klebsiella pneumoniae, Co-researcher, 2019 to 2021 (National)
  • Evaluation of antidiabetic, wound healing abilities and toxicity profile of Tinospora cordifolia extracts in streptozotocin-induced diabetic rats, Co-researcher, 2018 to 2019 (Taylor's University)
  • Isolation of quassinoids from the roots of Eurycoma longifolia Jack using semi-preparative high performance liquid chromatography method, Co-researcher, 2017 to 2019 (Taylor's University)
  • Design and development of Second Generation Smarter Nanocrystals for delivery of Gliclazide, Co-researcher, 2017 to 2019 (Taylor's University)
  • Synthesis and evaluation of isonicotinotinic acid hydrazine derivatives as antibacterial and antiviral agents, Project Leader, 2016 to 2018 (Taylor's University)
SUPERVISION
(Title of Thesis),(Name of Candidates),(Academic Level),(Role)
ONGOING
  • Phuna Zhi Xin, PhD/ Doctoral  (Co-supervisor (Internal))
  • Wang Yanan, PhD/ Doctoral  (Main Supervisor)
  • Chung Wan Yean, Master by Research  (Co-supervisor (Internal))
  • STEPHANIE A/P SANDANASAMY  (Main Supervisor)
  • RACHNA KRISHNAMOORTHY  (Co-supervisor (Internal))
  • WANG YANAN  (Main Supervisor)
  • UDYANEE JAYAWEERA  (Main Supervisor)
  • LAYLA FATHI YASSIN MOHAMED  (Main Supervisor)
COMPLETED
  • THE DIABETIC WOUND HEALING ABILITIES OF THE ETHANOLIC EXTRACT OF TINOSPORA CORDIFOLIA STEM IN STREPTOZOTOCIN NICOTINAMIDE INDUCED DIABETIC RATS, MICHELE FERNANDEZ A/P JOSEPH HATH  (Co-supervisor (Internal))
  • SYNTHESIS OF 2-HYDROXY-4-METHOXYACETOPHENONE SUBSTITUTED CHALCONE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS, TAN LI YING  (Main Supervisor)
  • THERAPEUTIC EFFICACY OF CURCUMIN-PIPERINE LOADED NANOCRYSTAL FOR MEMORY IMPAIRMENT AND GUT DYSBIOSIS IN STREPTOZOTOCIN-INDUCED ALZHEIMER'S DISEASE SPRAGUE DAWLEY RATS MODEL, PHUNA ZHI XIN  (Co-supervisor (Internal))
  • IN SILICO GENOME-SCALE METABOLIC MODELING AND IN VITRO STATIC TIME-KILL STUDIES OF EXOGENOUS METABOLITES ALONE AND WITH POLYMYXIN B AGAINST KLEBSIELLA PNEUMONIAE, CHUNG WAN YEAN  (Co-supervisor (Internal))
PRESENTATION
(Title),(Event),(Date Presented),(Organiser),(Level)
ORAL PRESENTER
  • Effect of extraction temperature on polyphenolic content and antioxidant potential of Gynura crepioides leaves, International Health and Medical Sciences Conference 2019, 08/03/2019 to 09/03/2019, Taylor's University and Griffith University (International)
OTHERS
  • Fabrication, In vitro Characterization and Drug Release Kinetics of Curcumin and Piperine loaded PLGA Nanocrystals, The Inaugural Monash International Health Science and Technology Conference, 16/06/2021 to 17/06/2021, Monash University, Malaysia. (International)
  • Metabolic Responses of Klebsiella pneumoniae upon Exogenous Metabolites Feeding using Genome Scale Metabolic Modeling, The Inaugural Monash International Health Science and Technology Conference, 16/06/2021 to 17/06/2021, Monash University, Malaysia. (International)
  • 2-Hydroxy-4-methoxyacetophenone substituted chalcones: Synthesis and biological evaluation as potential anticancer agents, The 6th International Electronic Conference on Medicinal Chemistry, 01/11/2020 to 30/11/2020, MDPI journal Pharmaceuticals 10.3390/ECMC2020-07442 (DOI) (International)
  • Gliclazide loaded PLGA-HPMC second generation nanocrystals for oral delivery: Design, development and in vitro performance characterization, International Health and Medical Sciences Conference 2019, 08/03/2019 to 09/03/2019, Taylor's University and Griffith University (International)
  • Participant , 2nd International Symposium on Bioinformatics, 20/12/2018 to 21/12/2018, Perdana University, Serdang, Malaysia. (International)
  • Gynura crepidioides Leaves Extract: An Antibacterial Study, 13th MPS-USM Scientific Conference, 03/11/2017 to 05/11/2017, Malaysian Pharmaceutical Society-Universiti Sains Malaysia  (National)
  • Polyphenolic content and antioxidant potential of Gynura procumbens and Gynura crepioides leaves: A comparison study, 5th International Postgraduate Conference on Pharmaceutical Sciences 2017, 17/05/2017 to 18/05/2017, UiTM (International)
AWARDS AND STEWARDSHIP
(Name of Award/Stewardship),(Award Category),(Awarding Institution),(Year Awarded),(Type of Award)
  • USM-Fellowship , Education, Universiti Sains Malaysia (USM), 2009 (Fellowship)