Curriculum Vitae

PERSONAL DETAILS

Dr Wong Yin How


ACADEMIC QUALIFICATION
(Qualification),(Institution)
  • Doctor of Philosophy, UNIVERSITY OF MALAYA, Malaysia
  • Bachelor of Science - Biochemistry, UNIVERSITY OF MALAYA, Malaysia
PROFESSIONAL MEMBERSHIP
(Organisation),(Role),(Duration),(Level)
  • Malaysia Chapter of Control Released Society (MyCRC), Member, 2017 to 2021 (National)
  • Malaysian Society of Biochemistry and Molecular Biology, Member, 2015 to 2021 (National)
AREAS OF EXPERTISE
(Area)
  • Three Dimensional (3D) Printing (Drug Delivery Device, Medical Phantom)
  • Targeted Cancer Therapy (Chemo- and Radiation Therapy)
  • Enzymology (Protein Structure Function and Protein Ligand Interaction)
  • Targeted Drug Delivery (Micro and Nano-carrier)
PUBLICATIONS
(Title of publication in APA style)
Article in Journals
2023
  • Sun, Z., Daring, D., Wong, Y. H., & Yeong, C. H. (2023). Development of personalised 3D printed abdominal aortic aneurysm models with use of different materials for clinical education and training in interventional radiology. Australasian Medical Journal(Online), 16(5), 632-638. (ISI-Indexed)
  • Alregib, A. H., Tan, H. Y., Wong, Y. H., Kasbollah, A., Wong, E. H., Abdullah, B. J. J., ... & Yeong, C. H. (2023). Development and physicochemical characterization of a biodegradable microspheres formulation loaded with samarium‐153 and doxorubicin for chemo‐radioembolization of liver tumours. Journal of Labelled Compounds and Radiopharmaceuticals. (ISI-Indexed)
  • Wong, Y. H., Ting, H. E., Ng, K. H., Abdullah, B. J. J., Pongnapang, N., & Yeong, C. H. (2023). Development of a Tissue Equivalent Gelatine Phantom for Accuracy Verification of Tissue Elasticity Measurement Using Shear Wave Elastography Ultrasound. Australasian Medical Journal (Online), 16(4), 584-590. (ISI-Indexed)
  • Wong, Y. H., Kasbollah, A., Abdullah, B. J. J., & Yeong, C. H. (2023). Facile Preparation of Samarium Carbonate-Polymethacrylate Microspheres as a Neutron-Activatable Radioembolic Agent for Hepatic Radioembolization. Pharmaceutics, 15(3), 877. (ISI-Indexed)
     
  • Tan, H. Y., Wong, Y. H., Kasbollah, A., Md Shah, M. N., Yahya, N., Abdullah, B. J. J., & Yeong, C. H. (2023). Evaluation of Therapeutic Efficacy and Imaging Capabilities of 153Sm2O3-Loaded Polystyrene Microspheres for Intra-Tumoural Radionuclide Therapy of Liver Cancer Using Sprague-Dawley Rat Model. Pharmaceutics, 15(2), 536. (ISI-Indexed)
  • Sun, Z., Wong, Y. H., & Yeong, C. H. (2023). Patient-Specific 3D-Printed Low-Cost Models in Medical Education and Clinical Practice. Micromachines, 14(2), 464. (ISI-Indexed)
  • Tan, H. Y., Wong, Y. H., Kasbollah, A., Md Shah, M. N., Perkins, A. C., & Yeong, C. H. (2023). Operational nuclear research reactors in the Asia-Pacific with potential for medical radionuclide production. Nuclear Medicine Communications, 44(4), 227-243. (ISI-Indexed)
     
  • Williams, A., Tillett, C., Wong, Y. H., Yeong, C. H., & Sun, Z. (2023). How 3D printing software enhances and rewards student learning of brain anatomy. Australasian Medical Journal (Online), 16(3), 552-555. (ISI-Indexed)
     
2022
  • Tan HY, Wong YH, Kasbollah A, Shah M, Abdullah BJ, Perkins AC, Yeong CH. Development of neutron-activated samarium-153-loaded polystyrene microspheres as a potential theranostic agent for hepatic radioembolization. Nuclear Medicine Communications. 2022 Jan 17. (ISI-Indexed)
     
  • Nazeer, M. N., Choo, H. L., Wong, Y. H., & Hon, H. J. (2022, May). Additively Manufactured Patient Specific Cranioplasty Implants with Antibacterial Properties. Journal of Physics: Conference Series (Vol. 2222, No. 1, p. 012009). IOP Publishing. (SCOPUS-Indexed)
2021
  • Lugova, H., Andoy-Galvan, J. A., Patil, S. S., Wong, Y. H., Baloch, G. M., Suleiman, A., ... & Chinna, K. (2021). Prevalence and associated factors of the severity of depression, anxiety and stress among low-income community-dwelling adults in Kuala Lumpur, Malaysia. Community mental health journal, 1-10. (ISI-Indexed)
  • Koh, Y. X., Choo, H. L., Wong, Y. H., & Yeong, C. H. (2021, December). Chemically modified polystyrene co-loaded with antimicrobial agents. In Journal of Physics: Conference Series (Vol. 2120, No. 1, p. 012012). IOP Publishing. (ISI-Indexed)
  • Abd Raziff, H. H., Tan, D., Tan, S. H., Wong, Y. H., Lim, K. S., Yeong, C. H., ... & Ahmad, H. (2021). Laser-heated needle for biopsy tract ablation: In vivo study of rabbit liver biopsy. Physica Medica, 82, 40-45. (ISI-Indexed)
     
  • Sun Z, Ng CK, Wong YH, Yeong CH. 3D-Printed Coronary Plaques to Simulate High Calcification in the Coronary Arteries for Investigation of Blooming Artifacts. Biomolecules. 2021;11(9):1307. (ISI-Indexed)
  • Tan D, Lim KS, Wong YH, Abd Raziff HH, Tan SH, Sulaiman N, Abdullah BJ, Ahmad H, Yeong CH. Multivariate Regression Between Hounsfield Unit Shift, Tissue Temperature, and Tissue Contraction: A Feasibility Study of Computed Tomography Thermometry. IEEE Transactions on Instrumentation and Measurement (2021), 22;70:1-9. (ISI-Indexed)
2020
  • Abd Raziff, H. H., Tan, D., Lim, K. S., Yeong, C. H., Wong, Y. H., Abdullah, B. J. J., ... & Ahmad, H. (2020). A temperature-controlled laser hot needle with grating sensor for liver tissue tract ablation. IEEE Transactions on Instrumentation and Measurement. doi: 10.1109/TIM.2020.2978920. (ISI-Indexed)
     
  • Wong, Y. H., Tan, H. Y., Kasbollah, A., Abdullah, B. J. J., Acharya, R. U., & Yeong, C. H. (2020). Neutron-activated biodegradable samarium-153 acetylacetonate-poly-L-lactic acid microspheres for intraarterial radioembolization of hepatic tumors. World Journal of Experimental Medicine, 10(2), 10. (SCOPUS-Indexed)
     
  • Etherton, D., Tee, L., Tillett, C., Wong, Y. H., Yeong, C. H., & Sun, Z. (2020). 3D visualization and 3D printing in abnormal gastrointestinal system manifestations of situs ambiguus. Quantitative Imaging in Medicine and Surgery, 1-7. (ISI-Indexed)
     
  • Sindi, R., Wong, Y. H., Yeong, C. H., & Sun, Z. (2020). Development of patient-specific 3D-printed breast phantom using silicone and peanut oils for magnetic resonance imaging. Quantitative Imaging in Medicine and Surgery, 10(6), 1237-1248. (ISI-Indexed)
     
  • Tan, H. Y., Yeong, C. H., Wong, Y. H., McKenzie, M., Kasbollah, A., Shah, M. N. M., & Perkins, A. C. (2020). Neutron-activated theranostic radionuclides for nuclear medicine. Nuclear Medicine and Biology; 90-91: 55-68. (ISI-Indexed)
     
  • Sindi, R., Wong, Y. H., Yeong, C. H., & Sun, Z. (2020). Quantitative Measurement of Breast Density Using Personalized 3D-Printed Breast Model for Magnetic Resonance Imaging. Diagnostics, 10(10), 793. (ISI-Indexed)
     
2019
  • Lau, I., Wong, Y. H., Yeong, C. H., Aziz, Y. F. A., Sari, N. A. M., Hashim, S. A., & Sun, Z. (2019). Quantitative and qualitative comparison of low-and high-cost 3D-printed heart models. Quantitative imaging in medicine and surgery, 9(1), 107. (ISI-Indexed)
     
  • Allan, A., Kealley, C., Squelch, A., Wong, Y. H., Yeong, C. H., & Sun, Z. (2019). Patient-specific 3D printed model of biliary ducts with congenital cyst. Quantitative Imaging in Medicine and Surgery, 9(1), 86. (ISI-Indexed)
     
  • Sun, Z., Lau, I., Wong, Y. H., & Yeong, C. H. (2019). Personalized Three-Dimensional Printed Models in Congenital Heart Disease. Journal of Clinical Medicine, 8(4), 522. (ISI-Indexed)
     
  • Wong, Y. H., Tan, H. Y., Kasbollah, A., Abdullah, B. J. J., Shah, M. N. M., & Yeong, C. H. (2019, June). Biodegradable Samarium-153–labelled microspheres for hepatic radioembolization: preparation, characterization and radiolabelling evaluation after neutron activation. Journal of Physics: Conference Series (Vol. 1248, No. 1, p. 012066). IOP Publishing. (ISI-Indexed)
  • Dong Leng Lee, Yin How Wong, Peng Long Cheah, Daryl Tan, Kok Sing Lim, Azlan Che Ahmad, Norshazriman Sulaiman, Basri Johan Jeet Abdullah, Chai Hong Yeong. (2019). Correlation between CT Number shift and tissue temperature change during radiofrequency ablation: an ex-vivo study using bovine liver. Journal of Physics: Conference Series (Vol. 1248, No. 1, p. 012039). IOP Publishing. (ISI-Indexed)
2018
  • Tan, D., Lim, K. S., Zaini, M. K. A., Yeong, C. H., Wong, Y. H., Yang, H. Z., & Ahmad, H. (2018). Phase derivative thermo-spatiogram for distributed temperature sensing based on Chirped Grating-Michelson Interferometer. Sensors and Actuators A: Physical. (ISI-Indexed)
     
2017
  • Choong, K.L. Wong, Y.H., Yeong, C.H., Gnanasuntharam, G.K., Goh, K.L., Yoong, B.K., Pongnapang, N., Abdullah, B.J.J. (2017). Elasticity characterization of liver cancers using shear wave ultrasound elastography: comparison between hepatocellular carcinoma and liver metastasis, Journal of Diagnostic Medical Sonography. 33(6), 481-488 (SCOPUS-Indexed)
     
  • Panicker, A, Abdullah, B.J.J., Yaakup, N.A., Wong, Y.H., Yeong, C.H., Omar, S.Z., Vijaynanthan, A. (2017). Evaluation of diffusion-weighted imaging and apparent diffusion coefficient mapping using different b-values for magnetic resonance-guided focused ultrasound surgery: A preliminary study for uterine fibroid and adenomyoma, Journal of Health and Translational Medicine. 20: 1-13.
     
2016
  • Wong, Y.H., Kadir, H.A., Tayyab, S. (2016). A comparative analysis of protein stabilizing potential of honey and simulated honey sugar cocktail, Protein & Peptide Letters, 23(10): 898-904. (ISI-Indexed)
  • Bortolotti, A., Wong, Y.H., Korsholm, S.S., Bahring, N.H.B., Bobone, S., Tayyab, S., van de Weert, M., & Stella, L. (2016). On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra, RSC Advances, 6, 112870-112876. (ISI-Indexed)
2015
  • Manoharan, P., Wong, Y.H., Tayyab, S. (2015). Stabilization of human serum albumin against urea denaturation by diazepam and ketoprofen, Protein & Peptide Letters. 22: 611–617. (ISI-Indexed)
  • Wong, Y.H., Kadir, H.A., Tayyab, S. (2015). Can intrinsic fluorescence be used as a spectral probe for protein denaturation studies in the presence of honey, Journal of Applied Spectroscopy 82: 845-848. (ISI-Indexed)
  • Wong, Y.H., Kadir, H.A., Tayyab, S. (2015). Targeting chemical and thermal stability of ovalbumin by simulated honey sugar cocktail, International Journal of Biological Macromolecules 73: 207–214. (ISI-Indexed)
2014
  • Wong, Y.H., Lim, C.H., Kadir, H.A., Tayyab, S. (2014). Towards increasing chemical and thermal stability of lysozyme with a simulated honey sugar cocktail, RSC Advances 4: 53891–53898. (ISI-Indexed)
2013
  • Wong, Y.H., Kadir, H.A., Tayyab, S. (2013). Honey-induced protein stabilization as studied by fluorescein isothiocyanate fluorescence, Scientific World Journal. Article ID 981902, 8 pages. (ISI-Indexed)
2012
  • Wong, Y.H., Tayyab, S. (2012). Protein stabilizing potential of simulated honey sugar cocktail under various denaturation conditions, Process Biochemistry. 47 (12), 1933-1943. (ISI-Indexed)
RESEARCH PROJECT
(Project title),(Role),(Duration),(Level)
  • Development of a physical activity and behavioural intervention framework for electronic cigarettes cessation through improvement of psychological well-being among university students in Malaysia : A mix method approach, Co-researcher, 2023 to 2026 (National)
  • Pre-clinical Testing of a New Theranostic Formulation (Sm-153-PHBV Microspheres) for Transarterial Radioembolization of Liver Cancer, Co-researcher, 2023 to 2025 (National)
  • Synergistic Anticancer Properties of a Novel Radioactive Holmium-166 and 5-Fluorouracil Loaded Folate Functionalized Calcium Carbonate Nanoparticles for Targeted Chemo-Radiotherapy of Colorectal Cancer, Project Leader, 2022 to 2025 (National)
  • Herbal extract supplements of Trigonella foenum-graecum, Withania somnifera and Lepidium meyenii for sexual health in healthy aging males: A randomised, double-blind, placebo-controlled, phase II clinical trial, Co-researcher, 2019 to 2024 (International)
  • Effect of high-dose-vitamin-B multivitamin supplement on neural connectivity and oxidative metabolism in healthy adults: A randomised, double-blind, placebo-controlled, phase II clinical trial , Co-researcher, 2019 to 2024 (International)
  • In Vitro and In Vivo Tests On Graphene Oxide- Porous Superparamagnetic Nanoparticles As Contrast Agents In Magnetic Resonance Imaging Under Hyperthermia Conditions, Co-researcher, 2017 to 2020 (Private)
SUPERVISION
(Title of Thesis),(Name of Candidates),(Academic Level),(Role)
COMPLETED
  • ., Daryl Tan, PhD/ Doctoral  (Co-supervisor (Internal))
  • ., HANI HAREIZA BINTI ABD RAZIFF, Master by Research  (Co-supervisor (Internal))
  • DEVELOPMENT OF A BIODEGRADABLE CHEMO-RADIOEMBOLIZATION FORMULATION LOADED WITH RADIONUCLIDE (SAMARIUM153) AND CHEMOTHERAPY DRUG (DOXORUBICIN) FOR IN VITRO CYTOTOXICITY TEST OF LIVER CANCER, ASSEEL HISHAM IBRAHIM ALREGIB  (Co-supervisor (Internal))
ONGOING
  • MUHAMMAD NOORAIMAN ZUFAYRI BIN MOHD NOOR  (Main Supervisor)
  • IDIL MOHAMED YUSUF  (Co-supervisor (Internal))
PRESENTATION
(Title),(Event),(Date Presented),(Organiser),(Level)
ORAL PRESENTER
  • Development of Flexible Radiotherapeutic Bandage Containing Samarium-153 for the Treatment of Skin Cancer, 20th Asia-Oceania Congress on Medical Physics (AOCMP) & 18th South-East Asia Congress of Medical Physics (SEACOMP), 03/12/2020 to 05/01/2021, Asia-Oceania Federation of Organizations for Medical Physics & Southeast Asian Federation of Organizations of Medical Physics (International)
  • Biodegradable Samarium-153 labelled Microspheres for Hepatic Intratumoral Radiotherapy: Preparation, Characterization and Radiolabeling Evaluation after Neutron Activation, 18th Asia-Oceania Congress of Medical Physics & 16th South-East Asia Congress of Medical Physics, 11/11/2018 to 14/11/2018, Malaysian Institute of Physics (International)
  • Computed Tomography-Based Thermometry for Temperature Mapping during Percutaneous Radiofrequency Ablation: Ex-vivo Investigation, 5th International Meeting on Frontiers of Physics (IMFP2017), 03/12/2017 to 07/12/2017, Malaysian Institute of Physics (International)
  • Urea-Induced Structural Transitions in Champedak Galactose-Binding Lectin, 40th Annual Conference of the Malaysian Society for Biochemistry & Molecular Biology, 10/06/2015 to 11/06/2015, Malaysian Society for Biochemistry & Molecular Biology (National)
  • Improved chemical and thermal stability of proteins in the presence of simulated honey sugar cocktail, 10th International Conference on Protein Stability, 07/05/2014 to 09/05/2014, International Conference on Protein Stability (International)
  • Interference of honey with protein s intrinsic fluorescence and honey-induced protein stabilization, International Conference on Biological and Chemical Sciences 2014 (ICBCS 2014), 29/03/2014 to 30/03/2014, International Conference on Biological and Chemical Sciences (International)
  • Fluorescein isothiocyanate as a probe to study protein denaturation in the presence of honey, 17th Biological Sciences Graduate Congress, 08/12/2012 to 10/12/2012, Bangkok, Thailand (International)
  • Structural stabilization of ovalbumin by simulated honey sugar cocktail against urea denaturation, 37th Annual Conference of the Malaysian Society for Biochemistry & Molecular Biology , 18/07/2012 to 19/07/2012, Malaysian Society for Biochemistry & Molecular Biology  (National)
INVITED SPEAKER
  • 3D Printing in Medicine: User s Experience Sharing, 3D Printing Workshop IHMSC 2019, 10/03/2019 to 10/03/2019, Taylor's University (International)
POSTER PRESENTER
  • Development of Samarium-153 Labelled Radiotracer for Gamma Scintigraphy of Whole Gastric-Intestinal Transit Study, International Health and Medical Sciences Conference, 08/03/2019 to 10/03/2019, Taylor's University (International)
  • Effect of Different 3D Printing Parameters on Radiological Properties of 3D Printed Models, International Health and Medical Sciences Conference, 08/03/2019 to 10/03/2019, Taylor's University (International)
  • Development of theranostics polymethacrylate based microparticles containing samarium-153 for internal radiation therapy of hepatocellular carcinoma, IUBMB Advanced School 2018, 17/06/2018 to 20/06/2018, International Union of Biochemistry and Molecular Biology (International)
  • Guanidine Hydrochloride-Denatured States of Bacillus licheniformis Alpha-Amylase Under Different Buffer Conditions, 40th Annual Conference of the Malaysian Society for Biochemistry & Molecular Biology, 10/06/2015 to 11/06/2015, Malaysian Society for Biochemistry & Molecular Biology (National)
  • Simulated honey sugar cocktail as a protein stabilizer, 9th International Conference on Protein Stability, 02/05/2012 to 04/05/2012, 9th International Conference on Protein Stability (International)
AWARDS AND STEWARDSHIP
(Name of Award/Stewardship),(Award Category),(Awarding Institution),(Year Awarded),(Type of Award)
  • Excellent Oral Presentation, Conference, Asia-Oceania Federation of Organizations for Medical Physics (AFOMP), 2020 (Best Oral)
  • Best Poster Award, Conference, Taylor's University, 2019 (Best Poster Award)
  • IUBMB General Fellowship, Conference, International Union of Biochemistry and Molecular Biology (IUBMB), 2018 (Fellowship)
  • Silver Award at the International Research Innovation Invention Solution Exposition, Exhibition/Invention, University of Malaya (UM), 2018 (Silver Adward)
CONTRIBUTION TO SOCIETY
(Contribution to Society),(Duration),(Level)
  • Production of 3D printed face shields and mask straps to Covid-19 front liners, 01/04/2020 to 30/06/2020 (Community)
COURSE ATTENDED
(Course Title),(Course Mode),(Date/Duration),(Level)
  • International Conference on Molecular Imaging and Clinical PET CT in the Era of Theranostics (IPET-2020), Research, 24/11/2020 to 26/11/2020 (International)
  • Good Clinical Practice Workshop - Clinical Investigation Centre (CIC), University of Malaya Medical Centre, Research, 07/03/2017 to 09/03/2017 (National)