Curriculum Vitae

PERSONAL DETAILS

Dr Tor Yin Sim


ADMINISTRATIVE DUTIES
(Role),(Level),(Duration)
  • Lecturer I, Faculty of Health & Medical Sciences, 24/08/2017 to present
ACADEMIC QUALIFICATION
(Qualification),(Institution)
  • Doctor of Philosophy, UNIVERSITI PUTRA MALAYSIA, Malaysia
  • Bachelor of Science (Biomedical Sciences), UNIVERSITI PUTRA MALAYSIA, Malaysia
PROFESSIONAL MEMBERSHIP
(Organisation),(Role),(Duration),(Level)
  • Malaysian Association for Cancer Research (MACR), Associate member, Since 2017 (National)
  • MALAYSIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, Associate member, 2017 to 2018 (National)
AREAS OF EXPERTISE
(Area)
  • Molecular Pharmacology
PUBLICATIONS
(Title of publication in APA style)
Article in Journals
2019
  • Increased fucoxanthin in Chaetoceros calcitrans extract exacerbates apoptosis in liver cancer cells via multiple targeted cellular pathway (SCOPUS-Indexed)
  • Isolation of Cardamonin and Pinostrobin Chalcone from the Rhizomes of Boesenbergia rotunda (L.) Mansf. and their Cytotoxic Effects on H-29 and MDA-MB-231 Cancer Cell Lines (SCOPUS-Indexed)
2018
  • Foo, J. B., Lim, J. H., Lor, Y. Z., Zainol, R., Dam, V. E., How, C. W., Low, M. L., Rahman, N. A., Beh, C. Y., Tor, Y. S., Yazan, L. S., 2018. Copper complex derived from S-benzyldithiocarbazate and 3-acetylcoumarin induced apoptosis in breast cancer cell. Biometals. p1-11. (ISI-Indexed)
  • Ong, Y. S., Yazan, L. S., Ng, W. K., Abdullah, R., Mustapha, N. M., Sapuan, S., Foo, J. B., Tor, Y. S., How, C. W., Abd Rahman, N., and Zakarial Ansar, F. H. (2018) Thymoquinone loaded in nanostructured lipid carrier showed enhanced anticancer activity in 4T1 tumor-bearing mice. Nanomedicine. 13:13, 1567-1582 (ISI-Indexed)
  • Yazan, L.S., Zainal., N.A., Ali, R.M., Zali, M.F.S.M., Ong, Y.S., Tor, Y.S., Gopalsamy, B., Ling, V.F., Sapuan, S., Esa, N., Haron, A.S., Ansar, F.H.Z., Mokhtar, A.M.A. and Alwi, S.S.S, 2018. Antiulcer properties of kelulut honey against ethanol-induced gastric ulcer. Pertanika Journal of Science and Technology. 26 (1): 121-132.
2016
  • Wan Nor Hafiza, W.A., Yazan, L.S., Tor, Y.S., Foo, J.B., Armania, N. and Rahman, H.S. (2016). Endoplasmic reticulum stress-induced apoptotic pathway and mitochondrial dysregulation in HeLa cells treated with dichloromethane extract of Dillenia suffruticosa, Pharmacognosy Magazine. 12(45): 86-95. (ISI-Indexed)
  • Ong, Y.S., Saiful Yazan, L., Ng, W.K., Noordin, M.M., Sapuan, S., Foo, J.B. and Tor, Y.S. (2016). Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice, International Journal of Nanomedicine. 11: 5905-5915 (ISI-Indexed)
  • Napsiah, A.R. Latifah, S.Y., Wibowo, A., Ahmat, N., Foo, J.B., Tor, Y.S., Yeap, S.K., Razali, Z.A., Ong, Y.S. and Fakurazi, S. (2016). Induction of apoptosis and G2/M arrest by ampelopsin E from Dryobalanops towards triple negative breast cancer cells, MDA-MB-231, BMC Complementary and Alternative Medicine 16: Article 354, 11 pages. (ISI-Indexed)
  • Yazan, L.S., Zali, M.F.S.M., Ali, R., Zainal, N.A., Esa, N., Sapuan, S., Ong, Y.S., Tor, Y.S., Gopalsamy, B., Voon, F.L., and Alwi, S.S.S. (2016). Chemopreventive properties and toxicity of kelulut honey in sprague dawley rats induced with azoxymethane, BioMed Research International, 2016: 1-6. (ISI-Indexed)
  • Foo, J.B., Yazan, L.S., Tor, Y.S., Wibowo, A., Ismail, N., Armania, N., Loh, S.P., Ismail, I.S., Cheah, Y.K. and Abdullah, R. (2016). Dillenia suffruticosa dichloromethane root extract induced apoptosis towards MDA-MB-231 triple-negative breast cancer cells. Journal of Ethnopharmacology, 187: 195-204. (ISI-Indexed)
2015
  • Latifah, S.Y., Ong, Y.S., Zaaba, N.E., Mohd Ali, Razana, Foo, J.B. and Tor, Y.S. (2015). Anti-breast cancer properties and toxicity of Dillenia suffruticosa root aqueous extract in BALB/c mice, Asian Pacific Journal of Tropical Biomedicine. 5(12): 1018-1026. (ISI-Indexed)
  • Tor, Y.S., Latifah, S.Y., Foo, J.B., Wibowo, A., Ismail, N., Cheah, Y.K., Abdullah, R., Ismail, M., Ismail, I.S. and Yeap, S.K. (2015). Induction of apoptosis in MCF-7 cells via oxidative stress generation, mitochondria-dependent and caspase-independent pathway by ethyl acetate extract of Dillenia suffruticosa, and its chemical profile. PLoS One, 10(6): e0127441. (ISI-Indexed)
  • Foo, J.B., Yazan, L.S., Tor, Y.S., Wibowo, A., Ismail, N., Armania, N., Loh, S.P., Ismail, I.S., Cheah, Y.K., Abdullah, R. (2015). Induction of cell cycle arrest and apoptosis by betulinic acid-rich fraction from Dillenia suffruticosa root in MCF-7 cells involved p53/p21 and mitochondrial signalling pathway. Journal of Ethnopharmocology, 166: 270-278. (ISI-Indexed)
2014
  • Foo, J.B., Latifah, S.Y., Tor, Y.S., Armania, N., Ismail, N., Imam, M.U., Yeap, S.K., Cheah, Y.K., Abdullah, R. and Ismail, M. (2014). Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways. BMC Complementary and Alternative Medicine, 14: 1-16. IF: 1.88 (ISI-Indexed)
2013
  • Armania, N., Latifah, S.Y., Ismail, I.S., Foo, J.B., Tor, Y.S., Ishak, N., Ismail, N. and Ismail, M. (2013). Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis. Molecules, 18: 13320-13339 (ISI-Indexed)
2012
  • Hamizah, S., Roslida, A.H., Fezah, O., Tan, K.L., Tor, Y.S. and Tan, C.I. (2012). Chemopreventive potential of Annona muricata L. leaves on chemically-induced skin papillomagenesis in mice. Asian Pacific Journal of Cancer Prevention, 13: 2533-2539. (ISI-Indexed)
RESEARCH PROJECT
(Project title),(Role),(Duration),(Level)
  • Development of human umbilical cord-derived Mesenchymal Stem Cells (hUCB-MSC) and exosomes for the treatment of Diabetes mellitus type 2, Co-researcher, 2019 to 2020 (Private)
  • Investigating the Role of Autophagy in Breast Cancer Cells Treated with Doxorubicin and Proteasome Inhibitor: Proof of Concept with Autophagy Inhibitor , Co-researcher, 2018 to 2020 (Taylor's University)
  • The role of RUNX3 and E-cadherin underlying epithelial to mesenchymal (EMT)-associated cellular plasticity in gastric cancer, Co-researcher, 2018 to 2019 (Taylor's University)
  • Copper as target for colorectal cancer therapeutics: Anti-cancer effect of copper (II) complex derived from S-benzyldithiocarbazate and 3-acetylcoumarin, Project Leader, 2018 to 2019 (Taylor's University)
SUPERVISION
(Title of Thesis),(Name of Candidates),(Academic Level),(Role)
ONGOING
  • NG CHU XIN  (Co-supervisor (Internal))
  • SATHIAVANI A/P ARIKRISHNAN  (Main Supervisor)
PRESENTATION
(Title),(Event),(Date Presented),(Organiser),(Level)
ORAL PRESENTER
  • Vitamin D receptor polymorphisms and risk of Major Depressive Disorder. , 29th World Congress of the International Association for Suicide Prevention (IASP) and The 21st Malaysian Conference on Psychological Medicine (MCMP), 18/07/2017 to 22/07/2017, International Association for Suicide Prevention Malaysian Psychiatric Association (International)
POSTER PRESENTER
  • Induction of apoptosis through oxidative stress-related pathways in MCF-7, human breast cancer cells, by ethyl acetate extract of Dillenia suffruticosa, 5th International Conference on Natural Products for Health and Beauty (NATPRO 5), 06/05/2014 to 08/05/2014, Natural Product Research Center of Excellence, Prince of Songkla Univeristy (International)
AWARDS AND STEWARDSHIP
(Name of Award/Stewardship),(Award Category),(Awarding Institution),(Year Awarded),(Type of Award)
  • Best Paper Award (Third Prize)., Conference, University of Malaya (UM), 2017 (Best Oral)
  • Best Poster Presentation Award, Conference, Universiti Putra Malaysia (UPM), 2014 (Best Poster Award)