Curriculum Vitae

PERSONAL DETAILS

Dr Ooi Yin Yin


ADMINISTRATIVE DUTIES
(Role),(Level),(Duration)
  • Lecturer I, Faculty of Health & Medical Sciences, 03/08/2015 to present
ACADEMIC QUALIFICATION
(Qualification),(Institution)
  • Doctor of Philosophy, NATIONAL UNIVERSITY OF SINGAPORE, Singapore
  • Master of Science (Immunobiology), UNIVERSITI PUTRA MALAYSIA, Malaysia
  • Bachelor of Science (Biomedical Sciences), UNIVERSITI PUTRA MALAYSIA, Malaysia
PROFESSIONAL MEMBERSHIP
(Organisation),(Role),(Duration),(Level)
  • Malaysian Society of Neurosciences (MSN), Life member, Since 2017 (National)
AREAS OF EXPERTISE
(Area)
  • Neuroinflammation
  • Cellular Immunology
PUBLICATIONS
(Title of publication in APA style)
Article in Journals
2023
  • Shi, T., Li, X., Zheng, J., Duan, Z., Ooi, Y. Y., Gao, Y., Wang, Q., Yang, J., Wang, L., & Yao, L. (2023). Increased SPRY1 expression activates NF-κB signaling and promotes pancreatic cancer progression by recruiting neutrophils and macrophages through CXCL12-CXCR4 axis. Cellular oncology (Dordrecht), 46(4), 969–985. (ISI-Indexed)
  • Ashwyn J, Yong QL, Ng BKN, Chye SM, Ling APK, Voon KGL, Ooi YY, Tiong YL, Koh RY. (2023). Anti-neuroinflammatory mechanism of safinamide in inhibiting lipopolysaccharide-induced microglial activation. Pharmaceutical Sciences Asia. 50(3), 211-219 (SCOPUS-Indexed)
  • Low ZX, Tan KL, Yong YK, Looi CY, Ooi YY. (2023). Tualang and Kelulut Honey Reduced Lipopolysaccharides-stimulated Inflammatory Responses of Microglia. Malaysian Journal of Medicine & Health Sciences. 19(3): 375-379. (SCOPUS-Indexed)
  • Ju Nn Oo, Rhun Yian Koh, Yong Qi Leong, Soi Moi Chye, Anna Pick Kiong Ling, Khuen Yen Ng, Kenny Gah Leong Voon, Yin Yin Ooi and Yee Lian Tiong. (2023). Neurotoxicity of salsolinol through apoptosis induction and oxidative stress in BV2 microglial cell. Current Topics in Toxicology
2022
  • Ooi YY, Chia AYY, Teoh ML, Lee SH, Tang YQ, Chua LL, Looi CY, Ng WK, Tor YS, Yong PVC. (2022). Redesigning Biomedical Science Practicum towards a New Frontier. International Journal of Information and Education Technology. 12(11): 1221-1228. (SCOPUS-Indexed)
2021
  • Teng JS, Ooi YY, Chye SM, Ling APK, Koh RY. (2021). Immunotherapies for Parkinson's disease: Progression of Clinical Development. CNS & Neurological Disorders - Drug Targets. 20(9):802-813. (ISI-Indexed)
  • Lai ZJ, Ooi YY, Ling APK, Chye SM, Koh RY. (2021). A mini review on neuroprotective effects of syzygium cumini. Journal of Medicine & Biomedical Research. 20(1):21-28.
2015
  • Ooi, YY., Dheen, ST., Tay, SSW. (2015). Paracrine effects of mesenchymal stem cells-conditioned medium on microglial cytokines expression and nitric oxide production, Neuroimmunomodulation. 22(4), 233-242. (ISI-Indexed)
2014
  • Jose, S., Tan, S.W., Ooi, Y.Y., Ramasamy, R., Vidyadaran, S. (2014). Mesenchymal stem cells exert anti-proliferative effect on lipopolysaccharide-stimulated BV2 microglia by reducing tumour necrosis factor-α levels. Journal of Neuroinflammation. 11,149-162. (ISI-Indexed)
2013
  • Ooi, YY., Rahmat, Z., Jose, S., Ramasamy, R., Vidyadaran, S. (2013). Immunophenotype and differentiation capacity of bone marrow-derived mesenchymal stem cells from CBA/Ca, ICR and Balb/c mice, World Journal of Stem Cells. 5(1), 34-42. (ISI-Indexed)
2010
  • Ooi, YY., Ramasamy, R., Rahmat, Z., Subramaiam, H., Tan, SW., Abdullah, M., Israf, DA., Vidyadaran, S. (2010). Bone marrow-derived mesenchymal stem cells modulate BV2 microglia responses to lipopolysaccharide, International Immunopharmacology. 10(12), 1532-1540. (ISI-Indexed)
2009
  • Vidyadaran, S., Ooi, YY., Subramaiam, H., Badiei, A., Abdullah, M., Ramasamy, R., Seow, HF. (2009). Effects of macrophage colony-stimulating factor on microglial responses to lipopolysaccharide and beta amyloid, Cellular Immunology. 25, 105-110. (ISI-Indexed)
Article in Proceeding
2019
  • Ooi YY, Soyza RM, Low ZX, Tan KL. (2019). The Immunomodulatory effects of Tualang and Kelulut honey on microglial cell activities. Malaysian Journal of Medicine & Health Sciences. Supplement 2, 15: 35-35. 1p (SCOPUS-Indexed)
RESEARCH PROJECT
(Project title),(Role),(Duration),(Level)
  • Profiling human salivary biomarker(s) panel as a non-invasive detection method for myocardial infarction (MI), Co-researcher, 2023 to 2025 (Taylor's University)
  • Elucidating anti-inflammatory potency and mechanism of miRNA-146a-enriched-exosomes derived from mesenchymal stem cells on microglial cells, Project Leader, 2023 to 2026 (National)
  • Investigation on antiviral effects and immune regulatory activity of Lactobacillus casei & Lactobacillus acidophilus live culture strains and probiotic secreted components against respiratory syncytial virus and rotavirus in vitro, Co-researcher, 2022 to 2023 (Private)
  • The role of RUNX3 and E-cadherin underlying epithelial to mesenchymal (EMT)-associated cellular plasticity in gastric cancer, Co-researcher, 2018 to 2019 (Taylor's University)
  • Copper as target for colorectal cancer therapeutics: Anti-cancer effect of copper (II) complex derived from S-benzyldithiocarbazate and 3-acetylcoumarin, Co-researcher, 2018 to 2019 (Taylor's University)
  • Developing a culture model of microglia-induced neurotoxicity, Co-researcher, 2017 to 2018 (Private)
  • Immunomodulatory and anti-inflammatory effects of Tualang and Kelulut honeys on activated microglial cells, Project Leader, 2017 to 2019 (Taylor's University)
SUPERVISION
(Title of Thesis),(Name of Candidates),(Academic Level),(Role)
ONGOING
  • Siti Sarah Omar Zaki, PhD/ Doctoral  (Co-supervisor (External))
  • ROMEL MARIO SOYZA  (Main Supervisor)
  • LEE SIN JYE  (Main Supervisor)
COMPLETED
  • IN VITRO HYPERGLYCEMIA WOUND HEALING MODEL AND ELUCIDATION OF ITS MECHANISM USING WHARTON JELLY'S MESENCHYMAL STEM CELLS CONDITIONED MEDIA, LAI WOON FUI  (Co-supervisor (Internal))
COURSE ATTENDED
(Course Title),(Course Mode),(Date/Duration),(Level)
  • Managing Workplace Stress, Research, 17/05/2017
  • Creating Work/Life Balance, Research, 17/05/2017
  • Rebuilding Trust, Research, 30/03/2017
  • Incorporating Future Ready Skills with Experiential Learning, Research, 15/05/2017 to 17/05/2017