Associate Professor Dr Chia Yoke Yin


Academic Qualification

  • Doctor of Phil - Molecular Medicine, MONASH UNIVERSITY, Malaysia
  • Bachelor Of Science In Biotechnology (Hons), MONASH UNIVERSITY, Malaysia
  • Bachelor Of Science (Biotechnology), MONASH UNIVERSITY, Malaysia

Professional Qualification

No records found

Areas of Expertise

  • Medical And Health Sciences, Complimentary/Alternative Medicine, Traditional Medicine And Natural Products
  • Medical And Health Sciences, Medical Biochemistry And Clinical Chemistry, Hormones
  • Biological Sciences, Biochemistry, Metabolic Pathways
  • Biotechnology, Molecular Biology, Molecular And Structural Biology
  • Biotechnology, Biopharmacy Biotechnology, Drug Discovery

Research Interest

  • Nutritional biochemistry/molecular biology/endocrinology in health and diseases Effect of compounds e.g. glycyrrhizic acid on lipid and carbohydrate metabolism Current research: Female reproductive system (diseases and disorders)/Molecular modeling [bioinformatics approaches]

Publications

2017
  • Molecular Docking Studies of Glycyrrhizic acid (GA), Glycyrrhetic acid (GE) and Glabridin (GLA) With Estrogen Receptors (Ers) (ISI-Indexed), Biosciences, Biotechnology Research Asia - Article in Journals
  • 2D-QSAR Analysis on Estrogen Receptor Alpha (ER ) and Beta (ER ) Agonists - Article in Proceeding
  • TWO-DIMENSIONAL QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP (2DQSAR) ANALYSIS ON ESTROGEN RECEPTOR ALPHA (ER ) AND BETA (ER ) AGONISTS (SCOPUS-Indexed), Malaysian Journal of Biochemistry & Molecular Biology - Article in Journals
  • DNA Microarray Analysis of Estrogen Responsive Genes in Ishikawa Cells by Glabridin (SCOPUS-Indexed), Biochemistry Insights - Article in Journals
2016
  • Molecular Docking And Ligand Binding Studies Of Glabridin As Estrogen Receptor-Alpha Activating Ligand - Article in Proceeding
  • The effects of glycyrrhizic acid and glabridin in the regulation of CXCL5 inflammation gene on acceleration of wound healing. (SCOPUS-Indexed), Asian Pacific Journal of Tropical Biomedicine - Article in Journals
2015
  • Effects of natural essential oil product in normal diet and high-fat-diet fed rats (ISI-Indexed), International Journal of Medicinal Plants and Alternative Medicine - Article in Journals
  • A review on Glycyrrhizic acid and Glabridin from the metabolic and female reproduction perspective - Article in Proceeding
  • Falling Ill Frequently, ONLY HEALTH - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
  • Sleep Hygiene, ONLY HEALTH - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
  • Twilight of the lecture?, New Straits Times - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
2014
  • Evaluation on the estrogenicity of Glabridin in a Human Endometrial Cell Line - Article in Proceeding
  • Glycyrrhizic acid modulates PCOS Conditions in DHT-induced rats - Article in Proceeding
2013
  • Estrogenic and anti-proliferative activity of water extract of Glycyrhizzic uralensis (licorice root) (ISI-Indexed), International Journal of Phytomedicine - Article in Journals
  • Therapeutic Effects of Glycyrrhizic Acid (ISI-Indexed), Natural Product Communication - Article in Journals
  • Molecular docking of glycyrrhizic acid to peroxisome proliferator activated receptor alpha - Article in Proceeding
  • Molecular docking of glycyrrhizic acid to peroxisome proliferator activated receptor gamma - Article in Proceeding
  • Combinatory Studies of Glabridin, Tamoxifen and Fulvestrant on Human Endometrium Carcinoma Cells - Article in Proceeding
2012
  • Amelioration of glucose homeostasis by glycyrrhizic acid through gluconeogenesis rate-limiting enzymes (ISI-Indexed), European Journal of Pharmacology - Article in Journals
  • Phytoestrogenic property of Labisia pumila for use as an estrogen replacement therapy agent, African Journal of Biotechnology - Article in Journals
  • Processed vs Organic, ONLY HEALTH - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
  • Polycystic ovary syndrome - a health topic in females today, ONLY HEALTH - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
  • Dreaded Diabetes, ONLY HEALTH - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
2009
  • Peroxisome Proliferator-Activated Receptor Gamma (PPAR ), Lipoprotein Lipase (LPL), serum lipid and HOMA-IR in rats given Glycyrrhizic acid (ISI-Indexed), PPAR Research - Article in Journals
  • Effects of Glycyrrhizic acid on 11 -Hydroxysteroid Dehydrogenase (11 HSD1 and 2) Activities and HOMA-IR in rats at different treatment periods (ISI-Indexed), Experimental and Clinical Endocrinology and Diabetes - Article in Journals
  • Lipoprotein Lipase Expression, Serum Lipid and Tissue Lipid Deposition in Orally-administered Glycyrrhizic Acid-treated Rats (ISI-Indexed), Lipids in Health & Disease - Article in Journals
  • Effects of Glycyrrhizic acid on lipoprotein lipase expression and lipid profile in rats - Article in Proceeding
  • Effects of Glycyrrhizic Acid on Peroxisome Proliferator-Activated Receptor Gamma (Total PPAR , PPAR 1, PPAR 2) Expressions and HOMA-IR in rats, Malaysian Journal of Biochemistry and Molecular Biology - Article in Journals
2008
  • Lipid profile, serum free fatty acids and lipid deposition in glycyrrhizic acid-treated rats - Article in Proceeding
  • Effects of glycyrrhizic acid on 11 - hydroxysteroid dehydrogenase type 1 and type 2 activities. - Article in Proceeding
  • Effects of the treatment period with glycyrrhizic acid on 11 -hydroxysteroid dehydrogenase type 1 activity in rats - Article in Proceeding
  • Homeostasis model of assessment insulin resistance (HOMAIR) and histological analysis on tissues of rats administered with glycyrrhizic acid - Article in Proceeding
2007
  • 11 -hydroxysteroid dehydrogenase type 1 activity in glycyrrhizic acid treated rats (ISI-Indexed) - Article in Proceeding
  • Blood glucose and serum insulin levels in glycyrrhizic acid treated rats (ISI-Indexed) - Article in Proceeding
  • Blood glucose levels and histological analysis of rats administered with glycyrrhizic acid - Article in Proceeding
2006
  • Urinary amino acid profiles in vegetarians and non-vegetarians, Malaysian Journal of Nutrition - Article in Journals
  • Serum and urinary macromolecules and micromolecules in young Malaysians - Article in Proceeding
  • Urinary nitrogenous compounds in vegetarian and non-vegetarians - Article in Proceeding

Research

  • Interferon gamma in regulating Programmed Death-1 Ligand-1 (PD-L1): A prognostic marker in Malaysian non-small cell lung carcinoma (NSCLC),  Co-researcher2019 to 2022, National
  • The role of Glycyrrhizic acid and glabridin on pigmentation as anti-melanogenesis in aging,  Project Leader2018 to 2020, Taylor's University
  • In silico prediction and in vitro validation of mauriporin-derived peptides as potential therapeutic anticancer agents,  Co-researcher2018 to 2019, Taylor's University
  • Prevention of neurological disorders (Alzheimer's disease) in ageing: A study of synergistic effects of natural plant compounds on the degeneration of -amyloid proteins,  Co-researcher2017 to 2021, Taylor's University
  • THE CORRELATION OF GASTROINTESTINAL BIOMARKER FROM URINE, BREATH AND BACTERIA CULTURE USING ELECTRONIC NOSE,  Co-researcher2015 to 2018, National
  • EVALUATION OF ANTIHYPERLIPIDEMIC by Thiallan Bioherbs,  Consultant2014, Private
  • GLYCYRRHIZIC ACID AS AN INTERVENTION THERAPY TO IMPROVE HYPERANDROGENISMS IN POLYCYTIC OVARIAN SYNDROME CONDITIONS,  Project Leader2013 to 2015, Taylor's University
  • DEVELOPMENT OF GLYCYRRHIZIC ACID ANALOGUES TO COMBAT TYPE 2 DIABETES MELLITUS,  Project Leader2012 to 2015, National
  • "ESTABLISHING A RELIABLE/REPRODUCIBLE ASSAY FOR ASSESSING ESTROGENIC ACTIVITY AND (2) TO SCREEN SELECTED EXTRACTS, FRACTIONS AND PHYTOCOMPOUNDS OBTAINED IN A MALAYSIAN PLANT.",  Project Leader2011 to 2012, Private
  • EFFECTS OF GLYCYRRHIZIC ACID ON INSULIN SENSITIZATION TO PREVENT OBESITY AND DIABETES IN POLYCYSTIC OVARY SYNDROME IN RATS,  Project Leader2011 to 2013, National

Awards and Stewardship

  • Taylor s University 2nd Place Most Active Module, Education, Taylor's University, Taylor s University 2nd Place Most Active Module , 2016
  • Invention, Innovation and Design of Flipped Teaching in Principles of Life Sciences , Competition, National University Carnival on E-Learning (NUCEL),Malaysia, Best Presentation , 2015
  • Anugerah Fasilitator e-Pembelajaran Terbaik, Competition, National University Carnival on E-Learning (NUCEL),Malaysia, Anugerah Fasilitator e-Pembelajaran Terbaik , 2015
  • Taylor s University Top 10 Most Active Modules, Education, Taylor's University, Taylor s University Top 10 Most Active Modules , 2015
  • School of Biosciences (SBS) Top 3 Most Active Modules, Education, Taylor's University, School of Biosciences (SBS) Top 3 Most Active Modules , 2015
  • President s Award , Services, Taylor's University, President s Award , 2015
  • Gold Award Recipient for Innovative Module Site, Education, Taylor's University, Gold Award Recipient for Innovative Module Site , 2015
  • Vice-Chancellor s Award Most Cited Academic, Special, Taylor's University, Vice-Chancellor s Award Most Cited Academic , 2014
  • Taylor s University Exemplary Meritorious Academic Staff Award, Services, Taylor's University, Taylor s University Exemplary Meritorious Academic Staff Award , 2013
  • 2010 Merck Young Scientist Award (Bioscience Category), Competition, Merck Sdn. Bhd., Young Scientist Award , 2010

Paper Presented

  • Molecular docking of glycyrrhizic acid to peroxisome proliferator activated receptor gamma, 24th Intervarsity Biochemistry Seminar (CONFERENCE), ORAL PRESENTER , 11/05/2013
  • Molecular docking of glycyrrhizic acid to peroxisome proliferator activated receptor alpha, 24th Intervarsity Biochemistry Seminar (CONFERENCE), ORAL PRESENTER , 11/05/2013
  • Estrogenic effects of labisia pumila extracts in human endometrial adenocarcinoma cell line, International Conference of Chinese Medicine (CONFERENCE), ORAL PRESENTER , 22/09/2012
  • Possible use of licorice root extract as a safe estrogen replacement agent, 37th Concf Malaysian Soc for Biochem and Mol Biol (CONFERENCE), ORAL PRESENTER , 18/07/2012
  • Possible use of licorice root extract as a safe estrogen replacement agent, 37th Concf Malaysian Soc for Biochem and Mol Biol (CONFERENCE), ORAL PRESENTER , 18/07/2012
  • Relation between peroxisome proliferator-activated receptor (PPAR ), lipoprotein lipase (LPL) and 11 -hydroxysteroid dehydrogenase (11 -HSD) in rats given glycyrrhizic acid, 34th Ann Concf Malaysian Soc for Biochem and Mol Biol. & 3rd ASEAN Biochemistry Conference (CONFERENCE), ORAL PRESENTER , 07/10/2009
  • Effects of Glycyrrhizic acid on lipoprotein lipase expression and lipid profile in rats, 34th Ann Concf Malaysian Soc for Biochem and Mol Biol. & 3rd ASEAN Biochemistry Conference (CONFERENCE), ORAL PRESENTER , 07/10/2009
  • Peroxisome proliferator- activated receptor gamma expression and blood pressure determination in glycyrrhizic acid-treated rats on high-fat diet, 34th Ann Concf Malaysian Soc for Biochem and Mol Biol. & 3rd ASEAN Biochemistry Conference (CONFERENCE), ORAL PRESENTER , 07/10/2009
  • Lipoprotein lipase expression, serum free fatty acid, lipid profile & lipid deposition of rats on high-fat diet given glycyrrhizic acid, 34th Ann Concf Malaysian Soc for Biochem and Mol Biol. & 3rd ASEAN Biochemistry Conference (CONFERENCE), ORAL PRESENTER , 07/10/2009
  • Lipoprotein lipase expression, serum free fatty acid, lipid profile & lipid deposition of rats on high-fat diet given glycyrrhizic acid, 34th Ann Concf Malaysian Soc for Biochem and Mol Biol. & 3rd ASEAN Biochemistry Conference (CONFERENCE), ORAL PRESENTER , 07/10/2009