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Associate Professor Dr Low Bin Seng


Academic Qualification

  • Doctor of Philosophy (Pharmaceutical Chemistry), UNIVERSITI SAINS MALAYSIA, Malaysia
  • Master of Science (Pharmacy), UNIVERSITI SAINS MALAYSIA, Malaysia
  • Bachelor of Science (Hons), UNIVERSITI PUTRA MALAYSIA, Malaysia

Professional Qualification

No records found

Areas of Expertise

  • Medical And Health Sciences, Public Health, Environmental And Occupational Health And Safety Sciences, Environmental Protection And Health Impact
  • Medical And Health Sciences, Medical Biochemistry And Clinical Chemistry, Hormones
  • Medical And Health Sciences, Pharmacy, Pharmacokinetics
  • Medical And Health Sciences, Pharmacology, Traditional Medicine And Natural Product
  • Medical And Health Sciences, Pharmacology, Toxicology

Research Interest

No records found

Publications

2024
  • Factors Associated with Sleep Disorders Among International University Students in Malaysia (SCOPUS-Indexed), Sleep and Vigilance - Article in Journals
  • Dopamine and central dopaminergic circuitry in neurodegenerative diseases: Roles and mechanisms of action of natural phytochemicals (ISI-Indexed), Pharmacological Research - Natural Products - Article in Journals
  • Stimulatory Effect of Eurycomanone from Eurycoma longifolia Jack roots on Dopamine Secretion in Human Neuroblastoma SH-SY5Y Cell Line (SCOPUS-Indexed), Natural Product Research - Article in Journals
2021
  • Influences of genetics, lifestyle and environment on obese and non-obese university students in Malaysia (SCOPUS-Indexed), Journal of Public Health - Article in Journals
2020
  • Regular menstruation and positive family history are primary dysmenorrhea risk factors among female university students in Malaysia (SCOPUS-Indexed), International Medical Journal - Article in Journals
  • Education background and monthly household income are factors affecting the knowledge, awareness and practice on haze pollution among Malaysians (SCOPUS-Indexed), Environmental Science Pollution Research - Article in Journals
2019
  • Fabrication of Second Generation Smarter PLGA Based Nanocrystal Carriers for Improvement of Drug Delivery and Therapeutic Efficacy of Gliclazide in Type-2 Diabetes Rat Model (ISI-Indexed), SCIENTIFIC REPORTS - Article in Journals
2017
  • Lignans of phyllanthus niruri solid dispersion: A potential alternative gout therapy (ISI-Indexed), International Journal of Pharmacology - Article in Journals
  • Polar quassinoids in standardized Eurycoma longifolia extract formulated into a lipid-based solid dispersion to improve rat sperm count (ISI-Indexed), Phytotherapy Research - Article in Journals
2016
  • Sleep pattern and health among electronic devices users and its relationship with users practice in Malaysia university community (ISI-Indexed), Sleep and Biological Rhythms - Article in Journals
2015
  • Decreased expression of alpha-2-HS glycoprotein in the sera of rats treated with Eurycoma longifolia extract (ISI-Indexed), Frontiers in Pharmacology - Article in Journals
  • The in vitro and in vivo anti-cancer activities of a standardized quassinoids composition from Eurycoma longifolia on LNCaP human prostate cancer cells (ISI-Indexed), PLoS One - Article in Journals
  • Current public awareness on the safety of traditional and complementary medicines (T&CM) in Malaysia (ISI-Indexed), European Journal of Integrative Medicine - Article in Journals
2014
  • Acute, reproductive toxicity and two-generation teratology studies of a standardized quassinoid-rich extract of Eurycoma longifolia Jack in Sprague-Dawley rats (ISI-Indexed), Phytotherapy Research - Article in Journals
2013
  • Standardized quassinoid-rich Eurycoma longifolia extract improved spermatogenesis and fertility in male rats via the hypothalamic-pituitary-gonadal axis (ISI-Indexed), Journal of Ethnopharmacology - Article in Journals
  • Eurycomanone, the major quassinoid in Eurycoma longifolia root extract increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis (ISI-Indexed), Journal of Ethnopharmacology - Article in Journals
2011
  • Physico-chemical effects of the major quassinoids in a standardized Eurycoma longifolia extract (Fr 2) on the bioavailability and pharmacokinetic properties, and their implication for oral antimalarial activity (ISI-Indexed), Natural Product Communications - Article in Journals
2009
  • The effect of Eurycoma longifolia on sperm quality of male rats (ISI-Indexed), Natural Product Communications - Article in Journals
2005
  • Bioavailability and pharmacokinetic studies of eurycomanone from Eurycoma longifolia Jack (ISI-Indexed), Planta Medica - Article in Journals

Research

  • A transcriptomic study of bioactive compounds isolated from bioactivity-guided fractionation of Eurycoma longifolia Jack on dopaminergic SH-SY5Y neuronal cell-line ,  Project Leader, 2021 to 2023, National
  • Effect of quassinoids isolated from the roots of Eurycoma longifolia Jack on the biosynthesis of serotonin and catecholamine: An in vitro and in silico studies ,  Project Leader, 2020 to 2021, Taylor's University
  • Isolation of quassinoids from the roots of Eurycoma longifolia Jack using semi-preparative high performance liquid chromatography method,  Project Leader, 2017 to 2019, Taylor's University
  • Role of arjunolic acid and chebulinic acid on cardio-metabolic functioning in MyD88 dependent TLR-4 downstream signaling pathways: Therapeutic and molecular approach,  Co-researcher, 2017 to 2020, Taylor's University
  • Design and development of Second Generation Smarter Nanocrystals for delivery of Gliclazide,  Co-researcher, 2017 to 2019, Taylor's University
  • Isolation and characterisation of immuno-modulatory properties of macluraxanthone ,  Co-researcher, 2014 to 2016, Taylor's University
  • The immuno-modulatory effects of Lactobacillus on macrophage responses to P. acnes,  Co-researcher, 2014 to 2015, Taylor's University

Awards and Stewardship

  • International Postgraduate Research Awards Seminar (InPRAS) , Competition, University of Malaya (UM), Judge for oral presentation , 2016
  • Best Thesis Awards, Special, Universiti Sains Malaysia (USM), Best Thesis , 2013

Paper Presented

  • Predictive value of entry qualification and entry CGPA scores on undergraduates MBBS students' performance in a private Malaysian medical institution , 21st Thai Medical Education Conference 2022 (CONFERENCE), Co-researcher , 26/01/2022 to 28/01/2022
  • Awareness of medical students on Human Papilloma Virus (HPV) related diseases in men and HPV immunization for men, World Conference on Public Health 2021 (CONFERENCE), Co-researcher , 26/11/2021 to 27/11/2021
  • Gynura crepioides leaves extract: an antibacterial study, 13th MPS Pharmacy Scientific Conference (CONFERENCE), Co-researcher , 03/11/2017 to 05/11/2017
  • Antifertility effect of Andrographis paniculata in rats, MPS Pharmacy Scientific Conference (CONFERENCE), POSTER PRESENTER , 31/10/2002 to 02/11/2002
  • Spermatogenic fertility studies of Eurycoma longifolia Jack (Tongkat Ali) extract, MPS Pharmacy Scientific Conference (CONFERENCE), ORAL PRESENTER , 10/10/2003 to 12/10/2003
  • Bioavailability and Pharmacokinetic Studies of the three bioactive quassinoids from Eurycoma longifolia Jack, 4th Asian Association of School of Pharmaceutical Sciences-MPS Pharmacy Scientific Conference, Penang, Malaysia (CONFERENCE), ORAL PRESENTER , 10/06/2009 to 13/06/2009
  • Eurycomanol, a reference marker for the quality control of commercial Tongkat Ali preparation, 4th Asian Association of School of Pharmaceutical Sciences-MPS Pharmacy Scientific Conference (CONFERENCE), Co-researcher , 10/06/2009 to 13/06/2009
  • Reproductive toxicity and teratological studies of standardized Eurycoma longifolia extract on rats, International Conference on Natural Product (CONFERENCE), ORAL PRESENTER , 10/12/2010 to 12/12/2010
  • The effects of a standardized quassinoid-rich root extract of Eurycoma longifolia Jack on rat spermatogenesis, 26th Scientific Meeting of Malaysian Society of Pharmacology & Physiology (CONFERENCE), ORAL PRESENTER , 18/05/2012 to 20/05/2012
  • Developing a validated HPLC phytochemical assay of Eurycoma longifolia and comparative studies on rat spermatogenesis between the organic and aqueous standardised extracts, 24th FAPA Congress (CONGRESS), Co-researcher , 13/09/2012 to 16/09/2012