Professor Dr Wong Eng Hwa


Academic Qualification

  • PHD IN MEDICAL SCIENCES, University of Malaya (UM), Malaysia
  • Bachelor Of Science (Microbiology), University Putra Malaysia, Malaysia

Professional Qualification

  • Good Clinical Practice, University of Malaya, Malaysia

Areas of Expertise

  • Medical And Health Sciences, Medical Microbiology, Bacteriology

Research Interest

No records found

Publications

2023
  • Risk Factors and Gender Difference in the Prediction of Ischemic Stroke in China. (ISI-Indexed), Journal of Natural Science, Biology and Medicine - Article in Journals
  • Anti-pancreatic lipase and anti-adipogenic effects of 5,7,3 ,4 ,5 -pentamethoxy and 6,2 ,4 -trimethoxy flavone - An in vitro study (ISI-Indexed), European Journal of Pharmacology - Article in Journals
  • Characterization of Physicochemical, Biological, and Chemical Changes Associated with Coconut Milk Fermentation and Correlation Revealed by 1H NMR-Based Metabolomics. (ISI-Indexed), Foods - Article in Journals
  • Hydroxylated polymethoxyflavones reduce the activity of pancreatic lipase, inhibit adipogenesis and enhance lipolysis in 3T3-L1 mouse embryonic fibroblast cells. (ISI-Indexed), Chemico-Biological Interactions - Article in Journals
  • The functions of Ca2+/calmodulin-dependent protein kinase II (CaMKII) in diabetes progression. (ISI-Indexed), Journal of Cell Communication and Signaling - Article in Journals
2022
  • In-silico genome-scale metabolic modeling and in-vitro static time-kill studies of exogenous metabolites alone and with polymyxin B against Klebsiella pneumoniae. (ISI-Indexed), Frontiers in Pharmacology - Article in Journals
  • The functions of Ca2+/calmodulin- dependent protein kinase II (CaMKII) in diabetes progression. (ISI-Indexed), Journal of Cell Communication and SignalingJournal of Cell Communication and Signaling - Article in Journals
  • Metabolomics based biomarker identification of anti-diabetes and anti-obesity properties of Malaysian herbs. (ISI-Indexed), Metabolomics - Article in Journals
  • Exogenous metabolite feeding on altering antibiotic susceptibility in Gram-negative bacteria through metabolic modulation: a review. (ISI-Indexed), Metabolomics - Article in Journals
  • An Overview of Antimicrobial Properties of Carbon Nanotubes-Based Nanocomposites. (ISI-Indexed), Advanced Pharmaceutical Bulletin - Article in Journals
2021
  • Novel antimicrobial development using genome-scale metabolic model of Gram-negative pathogens: A review. (ISI-Indexed), The Journal of Antibiotics - Article in Journals
  • Forkhead (FoxO1) signalling as a therapeutic target for type 2 diabetes and obesity. (ISI-Indexed), European Journal of Pharmacology - Article in Journals
  • The cross-talk of Hedgehog, PI3K and Wnt pathways in diabetes. (ISI-Indexed), Archives of Biochemistry and Biophysics - Article in Journals
  • Brown/Beige adipose tissues and the emerging role of their secretory factors in improving metabolic health: The batokines. (ISI-Indexed), Biochimie - Article in Journals
  • An Overview of Antimicrobial Properties of Carbon Nanotubes-Based Nanocomposites. (ISI-Indexed), Advanced Pharmaceutical Bulletin. - Article in Journals
2020
  • Mechanisms of action for the anti-obesogenic activities of phytochemicals. (ISI-Indexed), Phytochemistry - Article in Journals
  • Murine in vitro cellular models to better understand adipogenesis and its potential applications. (ISI-Indexed), Differentiation - Article in Journals
  • Elucidation of Antimicrobial Activity of Non-Covalently Dispersed Carbon Nanotubes. (ISI-Indexed), Materials - Article in Journals
  • High- versus low-dose conventional phototherapy for neonatal jaundice (Protocol). (ISI-Indexed), COCHRANE DATABASE OF SYSTEMATIC REVIEWS - Article in Journals
  • An overview of recent development in therapeutic drug carrier system using carbon nanotubes. (ISI-Indexed), Journal of Drug Delivery Science and Technology - Article in Journals
2019
  • Bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies. (ISI-Indexed), Drug Target Insights - Article in Journals
2018
  • SENARAI SEMAK PENILAIAN DAN PEMANTAUAN BIOSEKURITI MAKMAL KEBANGSAAN (Dalam Rangka Kerja Konvensyen Senjata Biology). Edisi Pertama, 2018 - Book
  • NATIONAL LABORATORY BIOSECURITY ASSESSMENT AND MONITORING CHECKLIST (In the Framework of Biological Weapons Convention) - Book
  • Alternative Approaches to Combat Medicinally Important Biofilm-Forming Pathogens. - Book Chapter
2017
  • Antimicrobial susceptibility and molecular characterization of Acinetobacter baumannii in Malaysia. (ISI-Indexed), International Journal of Antimicrobial Agents - Article in Journals
  • The role of Toll-like receptors in pathogenesis of pneumococci of various serotypes. (ISI-Indexed), International Journal of Antimicrobial Agents - Article in Journals
  • Adherence of Streptococcus pneumoniae and Expression Analysis of Neuraminidase Gene (NanA and NanB) after Interaction of A549 Human Lung Epithelial Cells with Pneumococcal Strains of Various Serotypes. (SCOPUS-Indexed), Malaysian Journal of Microbiology - Article in Journals
  • Antimicrobial susceptibility and molecular characterization of Acinetobacter baumannii in Malaysia (ISI-Indexed), INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS - Article in Journals
  • The role of Toll-like receptors in pathogenesis of pneumococci of various serotypes (ISI-Indexed), INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS - Article in Journals
2016
  • The emergence of Acinetobacter baumannii ST-6 multidrug resistant: A resilient biofilm producer, Malaysia (ISI-Indexed), Malaysian Journal of Microbiology - Article in Journals
2015
  • Evaluation of locomotor function and microscopic structure of the spinal cord in a mouse model of experimental autoimmune encephalomyelitis following treatment with syngeneic mesenchymal stem cells (ISI-Indexed), International Journal of Clinical and Experimental Pathology - Article in Journals
  • Investigating cell surface markers and differentiation potential of compact bone-derived mesenchymal stem cells. (SCOPUS-Indexed), International Journal of Stem Cell Research and Transplantation - Article in Journals
  • Differential expression of neuraminidase genes (NanA and NanB) in A549 human lung epithelial cells infected with pneumococcal strains of various serotypes. (ISI-Indexed), International Journal of Antimicrobial Agents - Article in Journals
  • Evaluation of the effect of Intravenous Mesenchymal Stem Cells on the Histology of Spinal Cord in Mouse treated with Myelin Oligodendrocyte Glycoprotein. (SCOPUS-Indexed), Malaysian Journal of Microscopy - Article in Journals
  • Evaluation of locomotor function and microscopic structure of the spinal cord in a mouse model of experimental autoimmune encephalomyelitis following treatment with syngeneic mesenchymal stem cells. (SCOPUS-Indexed), International Journal of Clinical and Experimental Pathology - Article in Journals
2014
  • Expression of Choline Binding Proteins in Streptococcus pneumoniae strains induced with Penicillin stress. (SCOPUS-Indexed), Pneumonia - Article in Journals
2010
  • Iron regulated outer membrane proteins (IROMPs) as potential targets against carbapenem-resistant Acinetobacter spp. isolated from a Medical Centre in Malaysia. (ISI-Indexed), Indian Journal of Medical Research - Article in Journals
2009
  • Disruption of ade B gene has a greater effect on resistance to meropenems than ade A gene in Acinetobacter spp. isolated from University Malaya Medical Centre. (ISI-Indexed), Singapore Medical Journal - Article in Journals
  • Detection and characterization of class I integrons among carbapenem-resistant isolates of Acinetobacter spp. in Malaysia (ISI-Indexed), Journal of Microbiology Immunology and Infection - Article in Journals
2007
  • Rapid Detection of Non-Enterobacteriaceae directly from positive blood culture using fluorescent in-situ hybridization. (ISI-Indexed), Indian Journal of Medical Microbiology - Article in Journals

Research

  • The potential role of extracellular membrane vesicles (EMV) as a vaccine candidate against pneumococcal infections,  Co-researcher2023 to 2025, National
  • Fostering Healthy Habits: An Interactive Menu Planning Software for Malaysian Secondary Boarding School Students using the Sufahani- Ismail Algorithm to Enhance Memory and Immunity,  Co-researcher2023 to 2025, National
  • Grant: Yayasan Penyelidikan Antartika Sultan Mizan (YPASM) Title: Correlation of bioactive compound extracted from commonly encountered Antarctic lichens against selected Gram positive and negative resistant bacteria: A novel insight in Medical Microbiology ,  Co-researcher2021 to 2023, National
  • Innovative Silver Nanoparticles Encapsulated with Phytochemicals for Targeting Candida glabrata Biofilm: Unravelling Its Modulatory Effects on Gene Expression, Host Oxidative Response and Antimicrobial Defense,  Co-researcher2021 to 2025, National
  • Innovative Silver Nanoparticles Encapsulated with Phytochemicals for Targeting Candida glabrata Biofilm: Unravelling Its Modulatory Effects on Gene Expression, Host Oxidative Response and Antimicrobial Defense,  Co-researcher2021 to 2024, National
  • Developing novel phytochemicals with Malaysia to solve medicinal needs,  Project Leader2021 to 2024, International
  • Developing novel phytochemicals with Malaysia to solve medicinal needs,  Co-researcher2021 to 2022, International
  • Grant: Geran Penyelidikan Fakulti (GPF) University of Malaya Title: Optimising polymyxin combinations with chloramphenicol derivatives in combatting MDR Klebsiella pneumoniae. ,  Co-researcher2020 to 2022, National
  • ASSESSMENT OF VERTICAL TRANSMISSION OF COVID-19 AND CLINICAL CHARACTERISTICS AND OUTCOMES OF THE INFECTED MOTHERS AND THEIR NEONATES ,  Co-researcher2020, National
  • Serial Monitoring of SARS-CoV2 in the Saliva of Patients (NMRR-20-902-54894),  Co-researcher2020, National

Awards and Stewardship

  • Best Booth Presentation, Exhibition/Invention, Taylor's University, Innovation Award , 2023
  • Silver Medal, Exhibition/Invention, Universiti Teknologi Mara (UITM), Innovation Award , 2023
  • Poster Jugde, Conference, University of Malaya (UM), Poster Judge , 2022
  • TUSOM Ambassador 2021 (ICON-MEGOPIC 27 February 2021), Conference, Taylor's University, TUSOM Ambassador 2021 , 2021
  • Gold Award for the OER (Educator) entitled Microbiology Laboratory Practical at Your Fingertips, Competition, Universiti Teknologi Mara (UITM), Gold Award , 2021
  • Long Service Award (10 years). Taylor s University Appreciation Year 2019. , Services, Taylor's University, Long Service Award , 2019
  • Outstanding Scientist in Microbiology, Special, Venus International Foundation, Outstanding Scientist in Microbiology , 2018
  • Outstanding Abstract Award, Conference, Korean Society of Infectious Diseases (KSID), Outstanding Abstract Award , 2017
  • Best Poster Award , Conference, Singapore NeuroScience Association, Best Poster Award , 2016
  • Best Oral Presentation Award, Conference, Malaysian Society for Microbiology, Best Oral , 2016

Paper Presented

  • Investigating the Role of Gut Dysbiosis in Alzheimer's Disease using Zebrafish Model, Malaysian Society of Parasitology and Tropical Medicine (MSPTM) Mid-Year Seminar 2023. "Advances in One Health: Strategies for Disease Prevention, Treatment, and Preparedness for Future Challenges in Tropical Medicine". (SEMINAR), ORAL PRESENTER , 25/09/2023 to 26/09/2023
  • Elucidation of the Novel Synergistic Effect of Lipasin and Collagen Peptide for the Treatment of Impaired Skin Wound Healing Using Diabetic Zebrafish Model, Malaysian Society of Parasitology and Tropical Medicine (MSPTM) Mid-Year Seminar 2023. "Advances in One Health: Strategies for Disease Prevention, Treatment, and Preparedness for Future Challenges in Tropical Medicine". (SEMINAR), ORAL PRESENTER , 25/09/2023 to 26/09/2023
  • In Vitro Synergistic Bactericidal Activity of Cefoperazone-Sulbactam Combined with Other Antimicrobial Agents Against Carbapenem-Resistant Acinetobacter baumannii, Malaysian Society of Parasitology and Tropical Medicine (MSPTM) Mid-Year Seminar 2023. "Advances in One Health: Strategies for Disease Prevention, Treatment, and Preparedness for Future Challenges in Tropical Medicine". (SEMINAR), ORAL PRESENTER , 25/09/2023 to 26/09/2023
  • Elucidation of Risk Factors Associated with Biochemistry Indicators to the Severity of Ischemic Stroke in Patients from Fuzhou First People's Hospital in China, Malaysian Society of Parasitology and Tropical Medicine (MSPTM) Mid-Year Seminar 2023. "Advances in One Health: Strategies for Disease Prevention, Treatment, and Preparedness for Future Challenges in Tropical Medicine". (SEMINAR), ORAL PRESENTER , 25/09/2023 to 26/09/2023
  • Extraction of Extracellular Membrane Vesicles (EMV) from Streptococcus pneumoniae using Ultracentrifugation, Ultrafiltration and Iodixanol Gradient Fractionation , International Conference on Pharmaceutical and Allied Sciences (CONFERENCE), POSTER PRESENTER , 11/03/2023 to 12/03/2023
  • Protein Identification of Extracellular Membrane Vesicles among Five Different Serotypes of Streptococcus pneumoniae. , 36th Symposium of the Malaysian Society for Microbiology 2023 (CONFERENCE), POSTER PRESENTER , 22/11/2023 to 23/11/2023
  • Metabolic responses of Klebsiella pneumoniae upon exogenous metabolites feeding using Genome-Scale Metabolic Modelling, Monash Initiate 2021 (CONFERENCE), ORAL PRESENTER , 16/06/2021 to 17/06/2021
  • Zebrafish obesity model: A study to investigate the Anti-adipogenic effects of Penta-Methoxy flavones , Asia Oceania Conference on Obesity & Malaysian Association For The Study of Obesity Scientific Conference. (AOCO-MASO 2021) (CONFERENCE), POSTER PRESENTER , 06/04/2021 to 08/04/2021
  • Synergistic antibacterial activity of novel exogenous metabolite-polymyxin combinations against Klebsiella pneumoniae, The Inaugural Monash International Health Science and Technology Conference 2021 (CONFERENCE), ORAL PRESENTER , 16/06/2021 to 17/06/2021
  • Detection and characterization of plasmid mediated Class 1 Integron among IMP-4 producing and non-producing carbapenem resistant Acinetobacter spp. from University Malaya Medical Centre. , 6th International Symposium on Antimicrobial Agents and Resistance (ISAAR), Singapore 2007. (CONFERENCE), POSTER PRESENTER , 06/03/2007 to 09/03/2007