Associate Professor Dr Wong Eng Hwa


Academic Qualification

  • PHD IN MEDICAL SCIENCES, University of Malaya (UM), Malaysia
  • Bachelor Of Science (Microbiology), University Putra Malaysia, Malaysia

Professional Qualification

  • Good Clinical Practice, University of Malaya, Malaysia

Areas of Expertise

  • Medical And Health Sciences, Medical Microbiology, Bacteriology

Research Interest

No records found

Publications

2021
  • The cross-talk of Hedgehog, PI3K and Wnt pathways in diabetes. (ISI-Indexed), Archives of Biochemistry and Biophysics - Article in Journals
  • Novel antimicrobial development using genome-scale metabolic model of Gram-negative pathogens: A review. (ISI-Indexed), The Journal of Antibiotics - Article in Journals
  • Carbon nanotubes toxicity: molecular mechanisms, signaling cascades and remedies in biomedical applications., Chemical Research in Toxicology - Article in Journals
  • Forkhead (FoxO1) signalling as a therapeutic target for type 2 diabetes and obesity. (ISI-Indexed), European Journal of Pharmacology - Article in Journals
2020
  • Mechanisms of action for the anti-obesogenic activities of phytochemicals. (ISI-Indexed), Phytochemistry - Article in Journals
  • Murine in vitro cellular models to better understand adipogenesis and its potential applications. (ISI-Indexed), Differentiation - Article in Journals
  • Elucidation of Antimicrobial Activity of Non-Covalently Dispersed Carbon Nanotubes. (ISI-Indexed), Materials - Article in Journals
  • High- versus low-dose conventional phototherapy for neonatal jaundice (Protocol). (ISI-Indexed), COCHRANE DATABASE OF SYSTEMATIC REVIEWS - Article in Journals
  • An overview of recent development in therapeutic drug carrier system using carbon nanotubes. (ISI-Indexed), Journal of Drug Delivery Science and Technology - Article in Journals
2018
  • SENARAI SEMAK PENILAIAN DAN PEMANTAUAN BIOSEKURITI MAKMAL KEBANGSAAN (Dalam Rangka Kerja Konvensyen Senjata Biology). Edisi Pertama, 2018 - Book
  • NATIONAL LABORATORY BIOSECURITY ASSESSMENT AND MONITORING CHECKLIST (In the Framework of Biological Weapons Convention) - Book
  • Alternative Approaches to Combat Medicinally Important Biofilm-Forming Pathogens. - Book Chapter
2017
  • Antimicrobial susceptibility and molecular characterization of Acinetobacter baumannii in Malaysia. (ISI-Indexed), International Journal of Antimicrobial Agents - Article in Journals
  • The role of Toll-like receptors in pathogenesis of pneumococci of various serotypes. (ISI-Indexed), International Journal of Antimicrobial Agents - Article in Journals
  • Adherence of Streptococcus pneumoniae and Expression Analysis of Neuraminidase Gene (NanA and NanB) after Interaction of A549 Human Lung Epithelial Cells with Pneumococcal Strains of Various Serotypes. (SCOPUS-Indexed), Malaysian Journal of Microbiology - Article in Journals
  • Antimicrobial susceptibility and molecular characterization of Acinetobacter baumannii in Malaysia (ISI-Indexed), INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS - Article in Journals
  • The role of Toll-like receptors in pathogenesis of pneumococci of various serotypes (ISI-Indexed), INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS - Article in Journals
2016
  • The emergence of Acinetobacter baumannii ST-6 multidrug resistant: A resilient biofilm producer, Malaysia (ISI-Indexed), Malaysian Journal of Microbiology - Article in Journals
2015
  • Evaluation of locomotor function and microscopic structure of the spinal cord in a mouse model of experimental autoimmune encephalomyelitis following treatment with syngeneic mesenchymal stem cells (ISI-Indexed), International Journal of Clinical and Experimental Pathology - Article in Journals
  • Evaluation of locomotor function and microscopic structure of the spinal cord in a mouse model of experimental autoimmune encephalomyelitis following treatment with syngeneic mesenchymal stem cells. (SCOPUS-Indexed), International Journal of Clinical and Experimental Pathology - Article in Journals
  • Investigating cell surface markers and differentiation potential of compact bone-derived mesenchymal stem cells. (SCOPUS-Indexed), International Journal of Stem Cell Research and Transplantation - Article in Journals
  • Differential expression of neuraminidase genes (NanA and NanB) in A549 human lung epithelial cells infected with pneumococcal strains of various serotypes. (ISI-Indexed), International Journal of Antimicrobial Agents - Article in Journals
  • Evaluation of the effect of Intravenous Mesenchymal Stem Cells on the Histology of Spinal Cord in Mouse treated with Myelin Oligodendrocyte Glycoprotein. (SCOPUS-Indexed), Malaysian Journal of Microscopy - Article in Journals
2014
  • Expression of Choline Binding Proteins in Streptococcus pneumoniae strains induced with Penicillin stress. (SCOPUS-Indexed), Pneumonia - Article in Journals
2010
  • Iron regulated outer membrane proteins (IROMPs) as potential targets against carbapenem-resistant Acinetobacter spp. isolated from a Medical Centre in Malaysia. (ISI-Indexed), Indian Journal of Medical Research - Article in Journals
2009
  • Disruption of ade B gene has a greater effect on resistance to meropenems than ade A gene in Acinetobacter spp. isolated from University Malaya Medical Centre. (ISI-Indexed), Singapore Medical Journal - Article in Journals
  • Detection and characterization of class I integrons among carbapenem-resistant isolates of Acinetobacter spp. in Malaysia (ISI-Indexed), Journal of Microbiology Immunology and Infection - Article in Journals
2007
  • Rapid Detection of Non-Enterobacteriaceae directly from positive blood culture using fluorescent in-situ hybridization. (ISI-Indexed), Indian Journal of Medical Microbiology - Article in Journals

Research

  • Grant: Yayasan Penyelidikan Antartika Sultan Mizan (YPASM) Title: Correlation of bioactive compound extracted from commonly encountered Antarctic lichens against selected Gram positive and negative resistant bacteria: A novel insight in Medical Microbiology ,  Co-researcher2021 to 2023, National
  • Grant: Geran Penyelidikan Fakulti (GPF) University of Malaya Title: Optimising polymyxin combinations with chloramphenicol derivatives in combatting MDR Klebsiella pneumoniae. ,  Co-researcher2020 to 2022, National
  • Serial Monitoring of SARS-CoV2 in the Saliva of Patients (NMRR-20-902-54894),  Co-researcher2020, National
  • ASSESSMENT OF VERTICAL TRANSMISSION OF COVID-19 AND CLINICAL CHARACTERISTICS AND OUTCOMES OF THE INFECTED MOTHERS AND THEIR NEONATES ,  Co-researcher2020, National
  • Dissecting the complex interplay between the Acinetobacter baumannii and lung epithelial cells using direct hybridization-based digital counting. ,  Co-researcher2018 to 2019, Taylor's University
  • Investigation of the role of Microbial Cell Preparation (Probiotics) in a clinical trial setting and Polymethoxy flavones as potential therapeutic agents in the management of obesity. ,  Project Leader2017 to 2022, Taylor's University
  • Molecular Characterisation of EPA genes in C.glabrata and its pathogenesis in antifungal resistance. ,  Co-researcher2017 to 2018, Taylor's University
  • Investigation and characterization of mesenchymal stem cells (MSC) conditioned media in an in vitro model of wound healing. ,  Co-researcher2017 to 2018, Taylor's University
  • Diagnosis of lung related diseases by assessing vibration patterns of structures in the thoracic cavity. ,  Co-researcher2017 to 2018, Taylor's University
  • Prevention of Neurological Disorders (Alzheimer s Disease) in ageing: A study of synergistic effects of natural plant compounds on the degeneration of -amyloid proteins. ,  Co-researcher2017 to 2021, Taylor's University

Awards and Stewardship

  • Outstanding Scientist in Microbiology, Special, Venus International Foundation, Outstanding Scientist in Microbiology , 2018
  • Outstanding Abstract Award, Conference, Korean Society of Infectious Diseases (KSID), Outstanding Abstract Award , 2017
  • Best Poster Award , Conference, Singapore NeuroScience Association, Best Poster Award , 2016
  • Best Oral Presentation Award, Conference, Malaysian Society for Microbiology, Best Oral , 2016
  • Best Poster Award , Conference, Malaysian Society for Microbiology, Best Poster Award , 2015
  • Silver Medal Award for Invention and Innovation , Exhibition/Invention, University of Malaya (UM), Silver Medal Award for Invention and Innovation , 2004

Paper Presented

  • Detection and characterization of plasmid mediated Class 1 Integron among IMP-4 producing and non-producing carbapenem resistant Acinetobacter spp. from University Malaya Medical Centre. , 6th International Symposium on Antimicrobial Agents and Resistance (ISAAR), Singapore 2007. (CONFERENCE), POSTER PRESENTER , 06/03/2007 to 09/03/2007
  • Molecular Epidemiology and Characterization of IMP-4 Metallo- Metallo- -lactamases in Multiresistant Acinetobacter spp. isolated in University Malaya Medical Centre, 9th Western Pacific Congress on Chemotherapy and Infectious Disease (CONFERENCE), POSTER PRESENTER , 01/12/2004 to 05/12/2004
  • Detection of IMP Metallo-beta-lactamases in Multiresistant Acinetobacter spp. isolated in University Malaya Medical Centre, 5th Annual Scientific Meeting of the College of Pathologist, AMM July 2004, held at (CONFERENCE), Main author and PG student , 15/07/2004 to 18/07/2004
  • Molecular Characterization of Acinetobacter baumannii Clonal Lineage using Multilocus Sequence Typing (MLST), 9th International Symposium on Antimicrobial Agents and Resistance (ISAAR 2013) (CONFERENCE), Corresponding author and Project Leader , 13/03/2013 to 15/03/2013
  • International Congress of the Malaysian Society for Microbiology 2013, Investigation of in-vitro biofilm formation by a multi-drug resistant Acinetobacter baumannii (MDR Ab). Presented at the , 12th 15th December 2013. (CONFERENCE), Corresponding author and Project Leader , 12/12/2013 to 15/12/2013
  • Proteomic Profiling Of Acinetobacter baumannii ATCC 19606 And Ab-13 Using 2-Dimensional Gel Electrophoresis., 17th Asia-Pacific Congress of Clinical Microbiology and Infection cum 8th International Infection Control Conference. (CONFERENCE), ORAL PRESENTER , 30/08/2018 to 02/09/2018
  • Carbapenem Resistant Enterobacteriaceae during Gastrointestinal Endoscopy: A Serious Menace. , International Conference on Biochemistry, Molecular Biology and Biotechnology 2018. 15th and 16th August 2018, (CONFERENCE), Corresponding author , 15/08/2018 to 16/08/2018
  • In vivo Expression of Acinetobacter baumannii Virulence Genes during Pneumonia Infection. , International Conference on Biochemistry, Molecular Biology and Biotechnology 2018. (CONFERENCE), Corresponding author and Project Leader , 15/08/2018 to 16/08/2018
  • Invitro antifungal susceptibility test using micro-broth dilution method of Amphotericin, B, Fluconazole, Voriconazole and Ketoconazole against Candida rugosa biofilm., 11th World Congress on Virology and Infectious Diseases. May 17-18, 2018, (CONFERENCE), Co-author , 17/05/2018 to 18/05/2018
  • Host Pathogen Interactions Of Pneumococcal Infection; Using A549 As A Model For Respiratory Infections., 11th International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) (CONFERENCE), Co-author , 15/04/2018 to 19/04/2018