Dr Naveen Kumar Hawala Shivashekaregowda


Academic Qualification

  • Doctor of Philosophy, UNIVERSITY OF SAINS MALAYSIA, Malaysia

Professional Qualification

No records found

Areas of Expertise

  • Medical And Health Sciences, Pharmacy, Medicinal Chemistry

Research Interest

No records found

Publications

2024
  • Implications of Low concentration Polymer on the Physical Stability of Glassy Griseofulvin: Role of the Segmental Mobility (ISI-Indexed), AAPS PharmSciTech - Article in Journals
  • Effects of polyvinyl pyrrolidone on the crystallization of amorphous griseofulvin: fracture and molecular mobility (ISI-Indexed), Journal of Applied Crystallography - Article in Journals
  • Stimulatory Effect of Eurycomanone from Eurycoma longifolia Jack roots on Dopamine Secretion in Human Neuroblastoma SH-SY5Y Cell Line (SCOPUS-Indexed), Natural Product Research - Article in Journals
2023
  • Anticancer effect of aromatic isoniazid derivatives in human gastric adenocarcinoma cells (ISI-Indexed), Toxicology and Applied Pharmacology - Article in Journals
  • Bacterial Foodborne Illness in Malaysia: Terminalia spp. as a Potential Resource for Treating Infections and Countering Antibiotic Resistance. (SCOPUS-Indexed), The Malaysian Journal of Medical Sciences - Article in Journals
2022
  • In-silico genome-scale metabolic modeling and in-vitro static time-kill studies of exogenous metabolites alone and with polymyxin B against Klebsiella pneumoniae. (ISI-Indexed), Frontiers in Pharmacology - Article in Journals
  • Recent development in nanocrystal based drug delivery for neurodegenerative diseases: Scope, challenges, current and future prospects (ISI-Indexed), Journal of Drug Delivery Science and Technology - Article in Journals
  • Nanoprotection from SARS-CoV-2: Would Nanotechnology Help in Personal Protection Equipment (PPE) to Control the Transmission of COVID-19? (ISI-Indexed), International Journal of Environmental Health Research - Article in Journals
  • Exogenous metabolite feeding on altering antibiotic susceptibility in Gram-negative bacteria through metabolic modulation: a review (SCOPUS-Indexed), Metabolomics - Article in Journals
2021
  • Novel antimicrobial development using genome-scale metabolic model of Gram-negative pathogens: A review. (ISI-Indexed), The Journal of Antibiotics - Article in Journals
  • The potential role of genus Tinospora in wound healing: a review, International Journal of Pharmacy and Pharmaceutical Sciences - Article in Journals
  • Cytotoxic Activity of Isoniazid Derivative in Human Breast Cancer Cells (ISI-Indexed), In Vivo - Article in Journals
2019
  • Identification of bioactive diterpenoid lactones using nuclear magnetic resonance from Andrographis paniculata (SCOPUS-Indexed), Pharmacognosy Research - Article in Journals
  • Gliclazide loaded PLGA-HPMC second generation nanocrystals for oral delivery: Design, development and in vitro performance characterization. (SCOPUS-Indexed), Malaysian Journal of Medicine and Health Sciences - Article in Journals
  • Effect of extraction temperature on polyphenolic content and antioxidant potential of Gynura crepioides leaves. (ISI-Indexed), Malaysian Journal of Medicine and Health Sciences - Article in Journals
  • Fabrication of Second Generation Smarter PLGA Based Nanocrystal Carriers for Improvement of Drug Delivery and Therapeutic Efficacy of Gliclazide in Type-2 Diabetes Rat Model. (ISI-Indexed), Scientific Reports - Article in Journals
2018
  • Polyphenolic content and antioxidant potential of Gynura procumbens and Gynura crepioidesleaves : A comparison study (SCOPUS-Indexed) - Article in Proceeding
  • Influence of Poloxamer 188 on Design and Development of Second Generation PLGA Nanocrystals of Metformin Hydrochloride (SCOPUS-Indexed), Nano Biomedicine and Engineering - Article in Journals
2017
  • Gynura crepioides leaves extract: An antibacterial study - Article in Proceeding
2015
  • Ichnocarpus frutescens: A valuable medicinal plant. (SCOPUS-Indexed), Pharmacologyonline - Article in Journals
2014
  • Synthesis of hydrophobic N-acylated isonicotinic acid hydrazide derivatives as potential enoyl-acyl carrier protein reductase (InhA) inhibitors. (ISI-Indexed), Medicinal Chemistry Research - Article in Journals
  • Synthesis and evaluation of isonicotinoyl hydrazone derivatives as antimycobacterial and anticancer agents. (ISI-Indexed), Medicinal Chemistry Research - Article in Journals
2013
  • Anti-tuberculosis activity of lipophilic isoniazid derivatives and their interactions with first-line anti-tuberculosis drugs (SCOPUS-Indexed), JOURNAL OF PHARMACY RESEARCH - Article in Journals
  • Effects of a lipophilic isoniazid derivative on the growth and cellular morphogenesis of Mycobacterium tuberculosis H37Rv., INTERNATIONAL JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES - Article in Journals
2010
  • (E)-N -(2, 3, 4-Trihydroxybenzylidene)isonicotinohydrazide dihydrate. (SCOPUS-Indexed), Acta Crystallographica Section E-Structure Reports Online - Article in Journals
  • (E)-N -(2-Benzyloxybenzylidene)isonicotinohydrazide methanol solvate monohydrate. (SCOPUS-Indexed), Acta Crystallographica Section E-Structure Reports Online - Article in Journals
  • Bis{(E)-N -[2,4-Bis(trifluromethyl)-benzylidene]isonicotin ohydrazide} monohydrate (SCOPUS-Indexed), Acta Crystallographica Section E-Structure Reports Online - Article in Journals
  • (E)-N -[(E)-3-(4-Hydroxy-3-methoxy phenyl ) allylidene ]isonico- tino hydrazide. (SCOPUS-Indexed), Acta Crystallographica Section E-Structure Reports Online - Article in Journals
  • (E )-N -[(E)-2-Methylpent-2-enylidene]isonicotinohydrazide. (SCOPUS-Indexed), Acta Crystallographica Section E-Structure Reports Online - Article in Journals
2009
  • N'-[(3-Methyl-2-thienyl)carbonyl]isonicotinohydrazide (SCOPUS-Indexed), Acta Crystallographica Section E-Structure Reports Online - Article in Journals
  • N -(Cyclohexanecarbonyl)isonicotinohydrazide (SCOPUS-Indexed), Acta Crystallographica Section E-Structure Reports Online - Article in Journals
  • (E)-N -(3-Benzyloxy-4-methoxybenzylidene) isonicotinohydrazide (SCOPUS-Indexed), Acta Crystallographica Section E-Structure Reports Online - Article in Journals

Research

  • Innovative Silver Nanoparticles Encapsulated with Phytochemicals for Targeting Candida glabrata Biofilm: Unravelling Its Modulatory Effects on Gene Expression, Host Oxidative Response and Antimicrobial Defense,  Co-researcher2021 to 2025, National
  • Innovative Silver Nanoparticles Encapsulated with Phytochemicals for Targeting Candida glabrata Biofilm: Unravelling Its Modulatory Effects on Gene Expression, Host Oxidative Response and Antimicrobial Defense,  Co-researcher2021 to 2024, National
  • A transcriptomic study of bioactive compounds isolated from bioactivity-guided fractionation of Eurycoma longifolia Jack on dopaminergic SH-SY5Y neuronal cell-line ,  Co-researcher2021 to 2024, National
  • Synergistic antibacterial activity of novel exogenous metabolite-polymyxin combinations against Klebsiella pneumoniae,  Co-researcher2019 to 2021, National
  • Evaluation of antidiabetic, wound healing abilities and toxicity profile of Tinospora cordifolia extracts in streptozotocin-induced diabetic rats,  Co-researcher2018 to 2019, Taylor's University
  • Isolation of quassinoids from the roots of Eurycoma longifolia Jack using semi-preparative high performance liquid chromatography method,  Co-researcher2017 to 2019, Taylor's University
  • Design and development of Second Generation Smarter Nanocrystals for delivery of Gliclazide,  Co-researcher2017 to 2019, Taylor's University
  • Synthesis and evaluation of isonicotinotinic acid hydrazine derivatives as antibacterial and antiviral agents,  Project Leader2016 to 2018, Taylor's University

Awards and Stewardship

  • USM-Fellowship , Education, Universiti Sains Malaysia (USM), Fellowship , 2009

Paper Presented

  • Fabrication, In vitro Characterization and Drug Release Kinetics of Curcumin and Piperine loaded PLGA Nanocrystals, The Inaugural Monash International Health Science and Technology Conference (CONFERENCE), Co-contributor , 16/06/2021 to 17/06/2021
  • Metabolic Responses of Klebsiella pneumoniae upon Exogenous Metabolites Feeding using Genome Scale Metabolic Modeling, The Inaugural Monash International Health Science and Technology Conference (CONFERENCE), Co-contributor , 16/06/2021 to 17/06/2021
  • 2-Hydroxy-4-methoxyacetophenone substituted chalcones: Synthesis and biological evaluation as potential anticancer agents, The 6th International Electronic Conference on Medicinal Chemistry (CONFERENCE), Corresponding author , 01/11/2020 to 30/11/2020
  • Effect of extraction temperature on polyphenolic content and antioxidant potential of Gynura crepioides leaves, International Health and Medical Sciences Conference 2019 (CONFERENCE), ORAL PRESENTER , 08/03/2019 to 09/03/2019
  • Gliclazide loaded PLGA-HPMC second generation nanocrystals for oral delivery: Design, development and in vitro performance characterization, International Health and Medical Sciences Conference 2019 (CONFERENCE), Participant and Co-researcher , 08/03/2019 to 09/03/2019
  • Participant , 2nd International Symposium on Bioinformatics (Symposium), Participant , 20/12/2018 to 21/12/2018
  • Polyphenolic content and antioxidant potential of Gynura procumbens and Gynura crepioides leaves: A comparison study, 5th International Postgraduate Conference on Pharmaceutical Sciences 2017 (CONFERENCE), Oral presentation- Corresponding Author , 17/05/2017 to 18/05/2017
  • Gynura crepidioides Leaves Extract: An Antibacterial Study, 13th MPS-USM Scientific Conference (CONFERENCE), Oral Presentation -Corresponding Author , 03/11/2017 to 05/11/2017