Professor Dr Chong Pei Pei

Subjects taught

·         Medical Biochemistry

·         Applied Molecular Biology

·         Microbiology

·         Genetic Engineering

Research Interest

·         Microbes in infectious diseases

·         Applications of -omics technologies in understanding host-pathogen interactions

·         Host genetics in cancer risks

·         Human papillomaviruses and associated diseases

·         Molecular diagnostics

Book Chapters

1.   Norhafizah Mohtarrudin and Chong Pei Pei. Crystals in the Joint. In: Problem based learning: Cases for medical students. Editors: Malina Osman, Rafidah Hod, Zamberi Sekawi. Vol. 1 No. 1. July 2007. pp.61-77; UPM Press (Selangor, Malaysia). ISSN: 1985-0042

2.   Chong Pei Pei, Eusni Rahayu Mohd Tohit, Syahrilnizam Abdullah. Unsightly eyelid. In. In: Problem based learning: Cases for medical students. (Editor: Hairuszah Ithnin) Vol. 3 No. 1 July 2012, pp.1-19; UPM Press. ISSN: 1985-0042

3.   Chong Pei Pei, Intan Hakimah bt Ismail, Maizaton Atmadini Abdullah. A Featherweight Child. In: Problem based learning: Cases for medical students. Vol 2, No 1 July 2008, pp. 55-71. UPM Press, ISSN: 1985-0042

 

Intellectual Property (Patent)

·         3 Malaysian patents granted (PI 20070524, PI 20083143, MY-163050-A),

·         3 Malaysian patents still pending

·         1 Japan patent (Reg. No. 5621992)

·         1 World patent filing WIPO WO/2010/021534 (Published, 2010)

·

Awards & Honours

·         PRPI 2010 (UPM Research & Innovation Exhibition) - 1 Silver medal and 1 Bronze medal

·         Best Research Programme Award – Institute of Bioscience (IBS) Innnovation Week 2010

·         PECIPTA 2009 organized by MOSTI  - Silver medal

·         Various silver and bronze medals, UPM PRPI 2002 – 2009

 

Research Grants Obtained

More than Ringgit Malaysia (RM) 1.6 million dollars cumulative grants obtained since 2001 as principal investigator from:

·         MOSTI E-Science Fund

·         MOHE Fundamental Research Grant Scheme (FRGS) grant

·         MOSTE TOP-Down BIOTEK fund (multi-institution, high value grant)

·         MAKNA Cancer Research Grant

·         UPM Research University Grants (RUGS)

 

Scholarly Activities/ Consultancy & Administration

·         Visiting Research Associate Professor, National University of Singapore (2013-2014)

·         Acting Deputy Dean (Research and Innovation), Faculty of Medicine and Health Sciences, Universiti Putra Malaysia; 1 April 2011- 16 May 2011; 27 October – 15 November 2011.

·         Research Coordinator (assisting the Deputy Dean), Faculty of Medicine and Health Sciences, Universiti Putra Malaysia; 2009-2011.

·         Head of Biochemistry Unit, Faculty of Medicine and Health Sciences, UPM; 2007-2009

·         Member of Panel Reviewer for accreditation of Masters and PhD Programs by Malaysian Qualifications Agency (MQA)

·         External examiner for Masters in Biotechnology and Masters in Biological Sciences program, International Medical University (IMU)

·         External Examiner for B.Sc. (Hons) Biomedical Science program in International Medical University

·         External exminer for Masters and PhD candidates in University Malaya, Universiti Kebangsaan Malaysia, Universiti Malaysia Sarawak.

·         External examiner for PhD candidate by University of Madras, India

 

 

·         Invited speaker

o   Invited Speaker, The Putra Cancer Research Symposium 2017

o   Invited Speaker, Pan-Asian Biomedical Sciences Conference 2014, Chinese University of Hong Kong, SAR Hong Kong

o   Invited Speaker, The 2nd International Symposium and Workshop on Functional Genomics and Structural Biology 2014

o   Invited Speaker, 20TH Malaysian Society for Molecular Biology and Biotechnology Scientific Meeting, 26-27th June 2013, University of Malaya

o   Invited Speaker, 8th National Infectious Diseases Seminar and Workshop, 2013

o   Kenote Speaker, 1st AMDI International Biohealth Science Conference (IBSC 2010), Bayview Beach Resort, Penang, Malaysia

o   Invited Speaker, 18th Annual Malaysian Congress of Obstetrical and Gynaecological Society of Malaysia in collaboration with Royal College of Obstetricians and Gynaecologists held at Genting International Convention Centre, Genting Highlands, from June 5-8, 2008

o   Invited Speaker, National Seminar and Workshop on Molecular Diagnosis and Typing of Bacterial Pathogens on 26th November, 2008

o   One of two invited speakers at “Gynofort Launch – 2% butoconazole” event organized by the Obstetrical & Gynaecological Society of Malaysia (sponsored by PM-Hyhens Pharmaceuticals Sdn Bhd) at Le Meridien Hotel, Kuala Lumpur on 10th November, 2007.

·         Chair of conference session

o   Session on Infectious Diseases and Immunology, Pan-Asian Biomedical Sciences Conference 2014, Chinese University of Hong Kong

Visibility

·         Media coverage in New Straitis Times, Berita Harian, Sin Chew Jit Poh Newspaper, and onTV3 on the innovation of CandiTect Kit, a rapid fungal detection kit for Candida species in September 2009

 

Student Supervision

·         Main supervisor for 8 Masters and 8 PhD students who have graduated in previously employed institution

·         Co-supervisor for 14 Masters and 19 PhD students who have graduated in previously employed institution



Academic Qualification

  • Doctor of Philosophy (Biochem. & Applied Molecular Biology), UMIST & THE VICTORIA UNIVERSITY OF MANCHESTER, United Kingdom
  • Bachelor of Science (Biochemistry), THE VICTORIA UNIVERSITY OF MANCHESTER, United Kingdom

Professional Qualification

No records found

Areas of Expertise

  • Biological Sciences, Genetics, Single Nucleotide Polymorphism (Snps)
  • Medical And Health Sciences, Medical Microbiology, Bacteriology
  • Biological Sciences, Microbiology, Mycology

Research Interest

No records found

Publications

2023
  • A comprehensive review of Cervical Cancer Screening Devices: the pros and the cons (SCOPUS-Indexed), Asian Pacific Journal of Cancer Prevention - Article in Journals
  • 3D printing of microbots, characterisation, and utilisation in combination with allicin against C. albicans biofilms (SCOPUS-Indexed), OpenNano - Article in Journals
  • Medicinal benefits, biological, and nanoencapsulation functions of riboflavin with its toxicity profile: A narrative review (SCOPUS-Indexed), Nutrition Research - Article in Journals
2022
  • Human herpesvirus 6A and 6B and polyomavirus JC and BK infections in renal cell carcinoma and their relationship with p53, p16INK4a, Ki-67, and nuclear factor-kappa B expression. (ISI-Indexed), Microbiology and Immunology - Article in Journals
  • Unraveling POLN germline mutations in familial nasopharyngeal carcinoma: Complementary evidence from gene association and molecular studies (ISI-Indexed), eBiomedicine - Article in Journals
  • Association of High-risk Human Papillomavirus Titer and Pathogenic Co-infections with Cervical Tissue Cytopathology. (SCOPUS-Indexed), Eurasian Journal of Medicine and Oncology - Article in Journals
  • Editorial: Differential Efficacy of Immune Checkpoint Inhibitors due to Age and Sex Factors (ISI-Indexed), FRONTIERS IN IMMUNOLOGY - Article in Journals
  • Epstein Barr virus infection is associated with the nuclear factor kappa B p65 signaling pathway in renal cell carcinoma (ISI-Indexed), BMC Urology - Article in Journals
2021
  • Omics-Based Analytical Approaches for Assessing Chicken Species and Breeds in Food Authentication (ISI-Indexed), Molecules - Article in Journals
  • Clinical accuracy and agreement between tympanic and forehead body temperature measurements for screening of patients with COVID-19 (ISI-Indexed), Journal of Clinical Nursing - Article in Journals
  • Mesenchymal Stem Cell-Derived Exosomes and MicroRNAs in Cartilage Regeneration: Biogenesis, Efficacy, miRNA Enrichment and Delivery (ISI-Indexed), Pharmaceuticals - Article in Journals
  • Inhibition of sessile and biofilm growth in various Aspergillus species by allicin associated with disruption to structural changes in cell wall (ISI-Indexed), International Journal of Infectious Diseases - Article in Journals
  • Allicin modulates expression of cell wall-related genes in Aspergillus fumigatus. (ISI-Indexed), International Journal of Infectious Diseases - Article in Journals
2020
  • Profiling of pornography addiction among children using EEG signals: A systematic literature review. (ISI-Indexed), COMPUTERS IN BIOLOGY AND MEDICINE - Article in Journals
  • Plasma and cell lysate proteins associated with treatment outcome in acute myeloid leukaemia. (SCOPUS-Indexed), Malaysian Journal of Medicine and Health Sciences - Article in Journals
  • Identification of Potential Genes for Benign Prostatic Hyperplasia and Prostate Cancer Susceptibility in Four X-chromosome Regions with High Frequency of Microvariant Alleles. (SCOPUS-Indexed), Asian Pacific Journal of Cancer Prevention - Article in Journals
  • A review of studies examining the association between genetic biomarkers (short tandem repeats and single-nucleotide polymorphisms) and risk of prostate cancer: the need for valid predictive biomarkers., Prostate International - Article in Journals
  • Mycobiome in the Gut: A Multiperspective Review (ISI-Indexed), Mediators of Inflammation - Article in Journals
2019
  • The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges (ISI-Indexed), Cells - Article in Journals
  • Cell surface proteins of Cryptococcus neoformans mediate adherence and internalisation into mammalian cells (SCOPUS-Indexed), Journal of Health And Translational Medicine - Article in Journals
  • Soy husk extract improves physical and biochemical parameters of obese diabetic rats through the regulation of PPAR expression (ISI-Indexed), Journal of Food Biochemistry - Article in Journals
  • Antifungal susceptibilities, biofilms, phospholipase and proteinase activities in the Candida rugosa complex and Candida pararugosa isolated from tertiary teaching hospitals. (ISI-Indexed), Journal of Medical Microbiology - Article in Journals
  • TREM-1 modulation produces positive outcome on the histopathology and cytokines release profile of Plasmodium berghei-infected mice (ISI-Indexed), Journal of Parasitic Diseases - Article in Journals
2018
  • Fas promoter -670 polymorphism and the risk of cervical cancer: A case-control study in multi-ethnic Malaysia, Journal of Epidemiological Research - Article in Journals
  • Association of hOGG1 Ser326Cys, ITGA2 C807T, TNF-A -308G>A and XPD Lys751Gln polymorphisms with the survival of Malaysian NPC patients (ISI-Indexed), Plos One - Article in Journals
  • Comparative Study of the Effects of Fluconazole and Voriconazole on Candida glabrata, Candida parapsilosis and Candida rugosa Biofilms. (ISI-Indexed), Mycopathologia - Article in Journals
  • Soy Husk Exerts Binary Actions against Hyperglycemia and Adipogenesis in cell-culture models., International Journal of Food Sciences and Nutrition - Article in Journals
  • Current perspective on Cervical Cancer and Human Papilloma Virus (HPV) vaccination in South East Asia, Asian Pacific Journal of Cancer Prevention - Article in Journals
2017
  • Haplotype CGC from XPD, hOGG1 and ITGA2 polymorphisms increases the risk of nasopharyngeal carcinoma in Malaysia. (ISI-Indexed), PLoS One - Article in Journals
  • Novel Candida albicans multilocus sequence typing (MLST) strains and potential Candida species hybridization in blood isolates of candidemia patients in Malaysia. (SCOPUS-Indexed), Malaysian Journal of Biochemistry and Molecular Biology - Article in Journals
2016
  • Small interfering RNA silencing of interleukin-6 in mesenchymal stromal cells inhibits multiple myeloma cell growth. (ISI-Indexed), Leukemia Research - Article in Journals
  • Growth, biofilm formation, antifungal susceptibility and oxidative stress resistance of Candida glabrata are affected by different glucose concentrations. (ISI-Indexed), Infection, Genetics and Evolution. - Article in Journals
  • Cocoa polyphenols treatment ameliorates visceral obesity by reduction lipogenesis and promoting fatty acid oxidation genes in obese rats through interfering with AMPK pathway. (ISI-Indexed), European Journal of Lipid Science and Technology - Article in Journals
  • CYP1A1 MspI polymorphism and cervical carcinoma risk in the multi-ethnic population of Malaysia: A case-control study. (SCOPUS-Indexed), Asian Pacific Journal of Cancer Prevention - Article in Journals
  • Comparative assessment of a self-sampling device and gynecologist sampling for cytology and HPV DNA detection in a rural and low resource setting: Malaysian experience. (SCOPUS-Indexed), Asian Pacific Journal of Cancer Prevention - Article in Journals
2015
  • The exoproteomes of clonally related Staphylococcus aureus strains are diverse. (ISI-Indexed), Annals of Microbiology - Article in Journals
  • The role of host microfilaments and microtubules during opsonin-independent interactions of Cryptococcus neoformans with mammalian lung cells. (ISI-Indexed), European Journal of Clinical Microbiology and Infectious Diseases. - Article in Journals
  • SNF3 as high affinity glucose sensor and its function in supporting the viability of Candida glabrata under glucose-limited environment. (ISI-Indexed), Frontiers in Microbiology. - Article in Journals
  • Comparative exoproteomics and host inflammatory response in Staphylococcus aureus skin and soft tissue infections, bacteremia, and subclinical colonization. (ISI-Indexed), Clinical and Vaccine Immunology - Article in Journals
  • Phylogenetic and transcripts profiling of glucose sensing related genes in Candida glabrata. (ISI-Indexed), Jundishapur Journal of Microbiology - Article in Journals
2014
  • Cloning, expression and purification of squalene synthase from Candida tropicalis in Pichia pastoris. (ISI-Indexed), Protein Expression and Purification - Article in Journals
  • In vivo and in vitro studies suggest a possible involvement of HPV infection in the early stage of breast carcinogenesis via APOBEC3B induction. (ISI-Indexed), PLoS ONE - Article in Journals
  • Immunoproteomic analysis of antibody response to cell wall-associated proteins of Candida tropicalis. (ISI-Indexed), Journal of Applied Microbiology - Article in Journals
  • Expression Analysis of Fatty Acid Biosynthetic Pathway Genes during Interactions of Oil Palm (Elaeis guineensis Jacq.) with the Pathogenic Ganoderma boninense and Symbiotic Trichoderma harzianum Fungal Organisms. (ISI-Indexed), Plant Molecular Biology Reporter - Article in Journals
  • Possible mechanisms of the antifungal activity of fluconazole in combination with terbinafine against Candida albicans. (ISI-Indexed), Pharmaceutical Biology - Article in Journals
2013
  • Analysis of Gln223Agr polymorphism of Leptin Receptor gene in type II diabetic mellitus subjects among Malaysians (ISI-Indexed), International Journal of Molecular Sciences. - Article in Journals
  • Modified silver staining in 2DE improves protein detection even at extremely low sample concentration. (ISI-Indexed), Electrophoresis - Article in Journals
  • Genotypically different clones of Staphylococcus aureus are diverse in the antimicrobial susceptibility patterns and biofilm formations. (ISI-Indexed), Biomed Research International - Article in Journals
  • Anti-hyphal formation property of allicin in suppression of Aspergillus fumigatus growth. (SCOPUS-Indexed), Malaysian Journal of Microbiology - Article in Journals
  • Antifungal activity of Rhizome coptidis and Alpinia galangal against Candida species. (SCOPUS-Indexed), Journal of Pure and Applied Microbiology. - Article in Journals

Research

  • A study on framework of a new remote personalised oral anticancer medication self-management model for patients with haematological malignancies,  Co-researcher2023 to 2025, National
  • New vaccination technology via skin absorption: Elucidation of skin penetration and immunogenicity profiles of an antigen model,  Co-researcher2022 to 2025, National
  • Innovative Silver Nanoparticles Encapsulated with Phytochemicals for Targeting Candida glabrata Biofilm: Unravelling Its Modulatory Effects on Gene Expression, Host Oxidative Response and Antimicrobial Defense,  Co-researcher2021 to 2024, National
  • Investigating anticancer activity of anti-MIRNA 21, MIR-145 mimics and Doxorubicin Cocktail packaged in nanoparticles conjugated with A6 Tumour-homing peptide for targeted inhibition of triple-negative breast cancer ,  Co-researcher2020 to 2024, National
  • Multi-use Illuminated Cervical Sampling Device (PapLight Pro) and Artificial Intelligence-driven Pap Smear Image Analysis,  Project Leader2019 to 2022, National
  • A framework for automated cancer cells detection using computer vision and deep learning algorithms,  Co-researcher2019 to 2023, National
  • Profiling of Pornography Addiction among Children using Neuro-Physiological Computational Model (NCM),  Co-researcher2019 to 2022, National
  • Preparation and evaluation of novel allicin-encapsulated 3-D printed microbots for targeting antimicrobial-resistant microbes,  Project Leader2019 to 2023, National
  • Carbon Nanotubes Nanocomposites in Combination with Allicin for Targeting Fungal Biofilm of C. Albicans, C. Neoformans and A. Fumigatus ,  Project Leader2018 to 2020, Taylor's University

Awards and Stewardship

No records found

Paper Presented

  • Targeting Triple-Negative Breast Cancer Cells with Anti-miRNA21 and Doxorubicin via Nanoparticles, UPM-MAKNA Cancer Research Laboratory CanRes Webinar Series (SEMINAR), INVITED SPEAKER , 26/05/2022 to 26/05/2022
  • Creating International Visibility, Organization for Women in Science in the Developing World, Malaysia National Chapter Relaunch (Relaunch of Malaysian Chapter for OWSD), INVITED SPEAKER , 21/08/2019 to 21/08/2019
  • Omics Approaches to Dissect host-pathogen interaction in Staphylococcus aureus infections, 7th International Conference on Bacteriology and Infectious Diseases (CONFERENCE), PLEANARY/KEYNOTE SPEAKER , 04/06/2018 to 05/06/2018