Associate Professor
- School of Biosciences
Faculty of Health & Medical Sciences - 56295650
- yokeyin.chia@taylors.edu.my
Associate Professor Dr Chia Yoke Yin
Academic Qualification
- Doctor of Phil - Molecular Medicine, Monash University, Malaysia
- Bachelor Of Science In Biotechnology (Hons), Monash University, Malaysia
- Bachelor Of Science (Biotechnology), Monash University, Malaysia
Professional Qualification
No records found
Areas of Expertise
- Medical And Health Sciences, Complimentary/Alternative Medicine, Traditional Medicine And Natural Products
- Medical And Health Sciences, Medical Biochemistry And Clinical Chemistry, Hormones
- Biological Sciences, Biochemistry, Metabolic Pathways
- Biotechnology, Molecular Biology, Molecular And Structural Biology
- Biotechnology, Biopharmacy Biotechnology, Drug Discovery
Research Interest
- Nutritional biochemistry/molecular biology/endocrinology in health and diseases Effect of compounds e.g. glycyrrhizic acid on lipid and carbohydrate metabolism Current research: Female reproductive system (diseases and disorders)/Molecular modeling [bioinformatics approaches]
Publications
2024
- Therapeutic properties of Inonotus obliquus (Chaga mushroom): A review. (ISI-Indexed), Mycology : An International Journal on Fungal Biology - Article in Journals
- A review on the cultivation, bioactive compounds, health-promoting factors and clinical trials of medicinal mushrooms Taiwanofungus camphoratus, Inonotus obliquus and Tropicoporus linteus (SCOPUS-Indexed), Fungal Biol Biotechnol - Article in Journals
2023
- In silico study of potential SARS-CoV-2 antagonist from Clitoria Ternatea (ISI-Indexed), International Journal of Health Sciences - Article in Journals
- Identification of Potentially Therapeutic Target Genes in Metastatic Breast Cancer via Integrative Network Analysis (SCOPUS-Indexed), Eurasian J. Med. Oncol - Article in Journals
- Insights from insulin resistance pathways: Therapeutic approaches against Alzheimer associated diabetes mellitus (SCOPUS-Indexed), Journal of Diabetes and its Complications - Article in Journals
2022
- Current Diabetes Technology and its Challenges (ISI-Indexed), Turkish Journal of Endocrinology and Metabolism - Article in Journals
- Network Analysis in the Identification of Genes Conferring Metastatic Potential in Hepatocellular Carcinoma (ISI-Indexed), Eurasian Journal of Medicine and Oncology - Article in Journals
- Redesigning Biomedical Science Practicum towards a New Frontier (SCOPUS-Indexed), International Journal of Information and Education Technology - Article in Journals
2021
- A review on advances of treatment modalities for Alzheimer's disease, Life Sciences - Article in Journals
- Perspective approaches on melanogenesis inhibition. (SCOPUS-Indexed), Dermatol Sin - Article in Journals
- Biological Properties of Stigmasterol and other Phytosterols (SCOPUS-Indexed), Malaysian Journal of Biochemistry & Molecular Biology - Article in Journals
2020
- Animal Venom-derived Antimicrobial Peptides: Novel AND Improved Weapon for Cancer Treatment (SCOPUS-Indexed), Malaysian Journal of Biochemistry & Molecular Biology - Article in Journals
- Anticancer Mechanisms of Bioactive Peptides (ISI-Indexed), Protein & Peptide Letters - Article in Journals
2019
- Synergistic Effects of Curcumin and Piperine as Potent Acetylcholine and Amyloidogenic Inhibitors With Significant Neuroprotective Activity in SH-SY5Y Cells via Computational Molecular Modeling and in vitro Assay (ISI-Indexed), Frontiers in Aging Neuroscience - Article in Journals
2018
- The Overview of Alzheimer Disease Intricate Mechanism: Amyloidopathy and its Toxicity, Journal of Biomedical Research and Reviews. - Article in Journals
2017
- Molecular Docking Studies of Glycyrrhizic acid (GA), Glycyrrhetic acid (GE) and Glabridin (GLA) With Estrogen Receptors (Ers) (ISI-Indexed), Biosciences, Biotechnology Research Asia - Article in Journals
- 2D-QSAR Analysis on Estrogen Receptor Alpha (ER ) and Beta (ER ) Agonists - Article in Proceeding
- TWO-DIMENSIONAL QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP (2DQSAR) ANALYSIS ON ESTROGEN RECEPTOR ALPHA (ER ) AND BETA (ER ) AGONISTS (SCOPUS-Indexed), Malaysian Journal of Biochemistry & Molecular Biology - Article in Journals
- DNA Microarray Analysis of Estrogen Responsive Genes in Ishikawa Cells by Glabridin (SCOPUS-Indexed), Biochemistry Insights - Article in Journals
2016
- Molecular Docking And Ligand Binding Studies Of Glabridin As Estrogen Receptor-Alpha Activating Ligand - Article in Proceeding
- The effects of glycyrrhizic acid and glabridin in the regulation of CXCL5 inflammation gene on acceleration of wound healing. (SCOPUS-Indexed), Asian Pacific Journal of Tropical Biomedicine - Article in Journals
2015
- Effects of natural essential oil product in normal diet and high-fat-diet fed rats (ISI-Indexed), International Journal of Medicinal Plants and Alternative Medicine - Article in Journals
- A review on Glycyrrhizic acid and Glabridin from the metabolic and female reproduction perspective - Article in Proceeding
- Falling Ill Frequently, ONLY HEALTH - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
- Sleep Hygiene, ONLY HEALTH - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
- Twilight of the lecture?, New Straits Times - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
2014
- Evaluation on the estrogenicity of Glabridin in a Human Endometrial Cell Line - Article in Proceeding
- Glycyrrhizic acid modulates PCOS Conditions in DHT-induced rats - Article in Proceeding
2013
- Estrogenic and anti-proliferative activity of water extract of Glycyrhizzic uralensis (licorice root) (ISI-Indexed), International Journal of Phytomedicine - Article in Journals
- Therapeutic Effects of Glycyrrhizic Acid (ISI-Indexed), Natural Product Communication - Article in Journals
- Molecular docking of glycyrrhizic acid to peroxisome proliferator activated receptor alpha - Article in Proceeding
- Molecular docking of glycyrrhizic acid to peroxisome proliferator activated receptor gamma - Article in Proceeding
- Combinatory Studies of Glabridin, Tamoxifen and Fulvestrant on Human Endometrium Carcinoma Cells - Article in Proceeding
2012
- Amelioration of glucose homeostasis by glycyrrhizic acid through gluconeogenesis rate-limiting enzymes (ISI-Indexed), European Journal of Pharmacology - Article in Journals
- Phytoestrogenic property of Labisia pumila for use as an estrogen replacement therapy agent, African Journal of Biotechnology - Article in Journals
- Processed vs Organic, ONLY HEALTH - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
- Polycystic ovary syndrome - a health topic in females today, ONLY HEALTH - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
- Dreaded Diabetes, ONLY HEALTH - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
2009
- Peroxisome Proliferator-Activated Receptor Gamma (PPAR ), Lipoprotein Lipase (LPL), serum lipid and HOMA-IR in rats given Glycyrrhizic acid (ISI-Indexed), PPAR Research - Article in Journals
- Effects of Glycyrrhizic acid on 11 -Hydroxysteroid Dehydrogenase (11 HSD1 and 2) Activities and HOMA-IR in rats at different treatment periods (ISI-Indexed), Experimental and Clinical Endocrinology and Diabetes - Article in Journals
- Lipoprotein Lipase Expression, Serum Lipid and Tissue Lipid Deposition in Orally-administered Glycyrrhizic Acid-treated Rats (ISI-Indexed), Lipids in Health & Disease - Article in Journals
- Effects of Glycyrrhizic acid on lipoprotein lipase expression and lipid profile in rats - Article in Proceeding
- Effects of Glycyrrhizic Acid on Peroxisome Proliferator-Activated Receptor Gamma (Total PPAR , PPAR 1, PPAR 2) Expressions and HOMA-IR in rats, Malaysian Journal of Biochemistry and Molecular Biology - Article in Journals
2008
- Lipid profile, serum free fatty acids and lipid deposition in glycyrrhizic acid-treated rats - Article in Proceeding
- Effects of glycyrrhizic acid on 11 - hydroxysteroid dehydrogenase type 1 and type 2 activities. - Article in Proceeding
- Effects of the treatment period with glycyrrhizic acid on 11 -hydroxysteroid dehydrogenase type 1 activity in rats - Article in Proceeding
- Homeostasis model of assessment insulin resistance (HOMAIR) and histological analysis on tissues of rats administered with glycyrrhizic acid - Article in Proceeding
2007
- 11 -hydroxysteroid dehydrogenase type 1 activity in glycyrrhizic acid treated rats (ISI-Indexed) - Article in Proceeding
- Blood glucose and serum insulin levels in glycyrrhizic acid treated rats (ISI-Indexed) - Article in Proceeding
- Blood glucose levels and histological analysis of rats administered with glycyrrhizic acid - Article in Proceeding
2006
- Urinary amino acid profiles in vegetarians and non-vegetarians, Malaysian Journal of Nutrition - Article in Journals
- Serum and urinary macromolecules and micromolecules in young Malaysians - Article in Proceeding
- Urinary nitrogenous compounds in vegetarian and non-vegetarians - Article in Proceeding
Research
- Elucidating anti-inflammatory potency and mechanism of miRNA-146a-enriched-exosomes derived from mesenchymal stem cells on microglial cells, Co-researcher, 2023 to 2026, National
- Profiling human salivary biomarker(s) panel as a non-invasive detection method for myocardial infarction (MI), Co-researcher, 2023 to 2025, Taylor's University
- Novel therapeutic option using synthetic mRNAs transcription factor in reprogramming stem cell into insulin producing cells , Project Leader, 2023 to 2025, Taylor's University
- Investigating Bioactive Anticancer Peptides from Scorpion Venom: Targeting Diverse Breast Cancer Cell Types , Co-researcher, 2023 to 2025, Taylor's University
- Identification and evaluation of diagnostic tumour-homing peptides specifically targeting metastatic breast cancer cells using phage-displayed peptide libraries, Co-researcher, 2020 to 2024, National
- Interferon gamma in regulating Programmed Death-1 Ligand-1 (PD-L1): A prognostic marker in Malaysian non-small cell lung carcinoma (NSCLC), Co-researcher, 2019 to 2023, National
- A novel approach of using mRNAs transcription factor in reprogramming human mesenchymal stem cells into insulin producing cells, Project Leader, 2019 to 2023, National
- Interferon gamma in regulating Programmed Death-1 Ligand-1 (PD-L1): A prognostic marker in Malaysian non-small cell lung carcinoma (NSCLC), Co-researcher, 2019 to 2023, National
- The role of Glycyrrhizic acid and glabridin on pigmentation as anti-melanogenesis in aging, Project Leader, 2018 to 2020, Taylor's University
- The role of Glycyrrhizic acid and glabridin on pigmentation as anti melanogenesis in aging , Project Leader, 2018 to 2020, Taylor's University
Awards and Stewardship
- Anugerah Khas Menteri Pengajian Tinggi: Rekabentuk Kurikulum Dan Penyampaian Inovatif (AKRI) 2022, Competition, Kementerian Pendidikan Malaysia, Other research awards , 2022
- Taylor s University 2nd Place Most Active Module, Education, Taylor's University, Taylor s University 2nd Place Most Active Module , 2016
- Invention, Innovation and Design of Flipped Teaching in Principles of Life Sciences , Competition, National University Carnival on E-Learning (NUCEL),Malaysia, Best Presentation , 2015
- Anugerah Fasilitator e-Pembelajaran Terbaik, Competition, National University Carnival on E-Learning (NUCEL),Malaysia, Anugerah Fasilitator e-Pembelajaran Terbaik , 2015
- Taylor s University Top 10 Most Active Modules, Education, Taylor's University, Taylor s University Top 10 Most Active Modules , 2015
- School of Biosciences (SBS) Top 3 Most Active Modules, Education, Taylor's University, School of Biosciences (SBS) Top 3 Most Active Modules , 2015
- President s Award , Services, Taylor's University, President s Award , 2015
- Gold Award Recipient for Innovative Module Site, Education, Taylor's University, Gold Award Recipient for Innovative Module Site , 2015
- Vice-Chancellor s Award Most Cited Academic, Special, Taylor's University, Vice-Chancellor s Award Most Cited Academic , 2014
- Taylor s University Exemplary Meritorious Academic Staff Award, Services, Taylor's University, Taylor s University Exemplary Meritorious Academic Staff Award , 2013
Paper Presented
- Molecular docking of glycyrrhizic acid to peroxisome proliferator activated receptor gamma, 24th Intervarsity Biochemistry Seminar (CONFERENCE), ORAL PRESENTER , 11/05/2013
- Molecular docking of glycyrrhizic acid to peroxisome proliferator activated receptor alpha, 24th Intervarsity Biochemistry Seminar (CONFERENCE), ORAL PRESENTER , 11/05/2013
- Estrogenic effects of labisia pumila extracts in human endometrial adenocarcinoma cell line, International Conference of Chinese Medicine (CONFERENCE), ORAL PRESENTER , 22/09/2012
- Possible use of licorice root extract as a safe estrogen replacement agent, 37th Concf Malaysian Soc for Biochem and Mol Biol (CONFERENCE), ORAL PRESENTER , 18/07/2012
- Possible use of licorice root extract as a safe estrogen replacement agent, 37th Concf Malaysian Soc for Biochem and Mol Biol (CONFERENCE), ORAL PRESENTER , 18/07/2012
- Relation between peroxisome proliferator-activated receptor (PPAR ), lipoprotein lipase (LPL) and 11 -hydroxysteroid dehydrogenase (11 -HSD) in rats given glycyrrhizic acid, 34th Ann Concf Malaysian Soc for Biochem and Mol Biol. & 3rd ASEAN Biochemistry Conference (CONFERENCE), ORAL PRESENTER , 07/10/2009
- Effects of Glycyrrhizic acid on lipoprotein lipase expression and lipid profile in rats, 34th Ann Concf Malaysian Soc for Biochem and Mol Biol. & 3rd ASEAN Biochemistry Conference (CONFERENCE), ORAL PRESENTER , 07/10/2009
- Peroxisome proliferator- activated receptor gamma expression and blood pressure determination in glycyrrhizic acid-treated rats on high-fat diet, 34th Ann Concf Malaysian Soc for Biochem and Mol Biol. & 3rd ASEAN Biochemistry Conference (CONFERENCE), ORAL PRESENTER , 07/10/2009
- Lipoprotein lipase expression, serum free fatty acid, lipid profile & lipid deposition of rats on high-fat diet given glycyrrhizic acid, 34th Ann Concf Malaysian Soc for Biochem and Mol Biol. & 3rd ASEAN Biochemistry Conference (CONFERENCE), ORAL PRESENTER , 07/10/2009
- Lipoprotein lipase expression, serum free fatty acid, lipid profile & lipid deposition of rats on high-fat diet given glycyrrhizic acid, 34th Ann Concf Malaysian Soc for Biochem and Mol Biol. & 3rd ASEAN Biochemistry Conference (CONFERENCE), ORAL PRESENTER , 07/10/2009