Associate Professor
- School of Biosciences
Faculty of Health & Medical Sciences - 03-56295091
- weihsum.yap@taylors.edu.my
Associate Professor Dr Yap Wei Hsum
Academic Qualification
- Doctor of Philosophy (Science), UNIVERSITY TUNKU ABDUL RAHAMAN, Malaysia
- Bachelor of Science (Hons) in Biotechnology, UNIVERSITI TUNKU ABDUL RAHMAN, Malaysia
Professional Qualification
- PGCHeTL, TAYLOR'S UNIVERSITY, Malaysia
Areas of Expertise
- Medical And Health Sciences, Pharmacology, Molecular Pharmacology
Research Interest
- Macrophage foam cells
- Skin models
Publications
2023
- In-Silico Study of Anticancer and Antimicrobial Peptides Derived from Cycloviolacin O2 (CyO2) (ISI-Indexed), In-Silico Study of Anticancer and Antimicrobial Peptides Derived from Cycloviolacin O2 (CyO2) - Article in Journals
- Hydroxychloroquine: Key therapeutic advances and emerging nanotechnological landscape for cancer mitigation (ISI-Indexed), CHEMICO-BIOLOGICAL INTERACTIONS - Article in Journals
- Editorial: Biofunctional Molecule Exploratory Research on Application in Food and Health (ISI-Indexed), MOLECULES - Article in Journals
2022
- Targeting Immune Senescence in Atherosclerosis (ISI-Indexed), International Journal of Molecular Sciences - Article in Journals
- Network Analysis in the Identification of Genes Conferring Metastatic Potential in Hepatocellular Carcinoma (ISI-Indexed), Eurasian Journal of Medicine and Oncology - Article in Journals
- Knowledge transfer of eLearning objects: Lessons learned from an intercontinental capacity building project (ISI-Indexed), Plos One - Article in Journals
- Editorial: The genetics of human Mendelian skin disorders (ISI-Indexed), frontiers in genetics - Article in Journals
- Integrated Assessment of Macrophage Lipids Homeostasis Omics Data: Identification of Potential Genes and Pathways in Atherosclerosis (SCOPUS-Indexed), Progress in Drug Discovery & Biomedical Science - Article in Journals
2021
- Participatory Approach in Reusable Learning Object (RLO) Development Using ASPIRE Framework: Taylor's University's Experience - Book Chapter
- An Overview of the Bioactivities of Gedunin - Book Chapter
- In vitro evaluation of the involvement of Nrf2 in maslinic acid-mediated anti-inflammatory effects in atheroma pathogenesis (ISI-Indexed), LIFE SCIENCES - Article in Journals
- Prioritising topics for developing e-learning resources in healthcare curricula: A comparison between students and educators using a modified Delphi survey (ISI-Indexed), Plos One - Article in Journals
- Biological Activities of Snowdrop (Galanthus spp., Family Amaryllidaceae) (ISI-Indexed), Frontiers in Pharmacology - Article in Journals
2020
- Anticancer Mechanisms of Bioactive Peptides (ISI-Indexed), Protein & Peptide Letters - Article in Journals
- Angelicin A Furocoumarin Compound With Vast Biological Potential (ISI-Indexed), FRONTIERS IN PHARMACOLOGY - Article in Journals
- Hyaluronic Acid-Mediated Drug Delivery System Targeting for Inflammatory Skin Diseases: A Mini Review (ISI-Indexed), FRONTIERS IN PHARMACOLOGY - Article in Journals
- Maslinic acid suppresses macrophage foam cells formation: Regulation of monocyte recruitment and macrophage lipids homeostasis (ISI-Indexed), Vascular Pharmacology - Article in Journals
- Microalgae as Potential Anti-inflammatory Natural Product against Human Inflammatory Skin Diseases (ISI-Indexed), Frontiers in Pharmacology - Article in Journals
2019
- Combining Understanding of Immunological Mechanisms and Genetic Variants Toward Development of Personalized Medicine for Psoriasis Patients (ISI-Indexed), Frontiers in Genetics - Article in Journals
- An Optimized Cosmetic Screening Assay for Ultraviolet B (UVB) Protec-tive Property of Natural Products, Progress in Drug Discovery & Biomedical Science - Article in Journals
- Formononetin: A Review of Its Anticancer Potentials and Mechanisms (ISI-Indexed), FRONTIERS IN PHARMACOLOGY - Article in Journals
- Bioactivity evaluation of bio-hydroxyapatite derived from Spanish mackerel in composite scaffolds for bone tissue engineering (ISI-Indexed) - Article in Proceeding
- Model of Experimentation for Photoprotective Properties of Natural Products Against Ultraviolet C (UVC) Damage: A Case Study On Rosmarinic Acid, Progress in Drug Discovery & Biomedical Science - Article in Journals
2018
- A reliable and affordable 3D tumor spheroid model for natural product drug discovery: a case study of curcumin, Progress in Drug Discovery & Biomedical Science - Article in Journals
- Maslinic acid suppresses macrophage foam cell formation via inhibition of LDL oxidation and cholesterol efflux (ISI-Indexed) - Article in Proceeding
- Maslinic acid modulates secreted phospholipase A2-IIA (sPLA2-IIA)-mediated inflammatory effects in macrophage foam cells formation (ISI-Indexed), Journal of Biosciences - Article in Journals
- Differential effects of sPLA2-GV and GX on cellular proliferation and lipid accumulation in HT29 colon cancer cells (ISI-Indexed), Molecular and Cellular Biochemistry - Article in Journals
- Resveratrol Potential Antibacterial Agent against Foodborne Pathogens (ISI-Indexed), FRONTIERS IN PHARMACOLOGY - Article in Journals
2017
- Oxidative Stress in Cardiovascular Diseases: Involvement of Nrf2 Antioxidant Redox Signaling in Macrophage Foam Cells Formation (ISI-Indexed), International Journal of Molecular Sciences - Article in Journals
2016
- Inhibition of Human Group IIA-Secreted Phospholipase A2 and THP-1 Monocyte Recruitment by Maslinic Acid. Lipids (ISI-Indexed), Lipids - Article in Journals
2015
- Mechanistic Perspectives of Maslinic Acid in Targeting Inflammation (ISI-Indexed), Biochemistry Research International - Article in Journals
Research
- New vaccination technology via skin absorption: Elucidation of skin penetration and immunogenicity profiles of an antigen model, Co-researcher, 2022 to 2025, National
- Curcumin analogues with N-methyl 4-piperidone linker suppress immune functions and MyD88-dependent NF-kB/MAPKs/ PI3-Akt signaling pathways in LPS-primed macrophages, Co-researcher, 2020 to 2024, National
- Identification and evaluation of diagnostic tumour-homing peptides specifically targeting metastatic breast cancer cells using phage-displayed peptide libraries, Co-researcher, 2020 to 2024, National
- Antioxidative potential amphiphile-modified low molecular weight hyaluronic acid (LMWHA) loaded with kojic acid ester (KAE) nanoemulsion, Co-researcher, 2019 to 2022, National
- Unraveling the role of cellular senescence marker p16INK4a in atherosclerotic lesion fatty streaks foam cells formation, Project Leader, 2019 to 2023, National
- Preparation and characterisation of polyvinyl alcohol with natural hydroxyapatite from fish bone as biocomposite nanomaterial, Co-researcher, 2018 to 2020, Taylor's University
- In vitro evaluation of polar and tropical microalgae extracts as anti-oxidative and de-pigmenting agents in cosmeceutical products, Co-researcher, 2018 to 2020, Taylor's University
- In silico prediction and in vitro validation of mauriporin-derived peptides as potential therapeutic anticancer agents, Co-researcher, 2018 to 2019, Taylor's University
- Investigating the Modulatory Effects of Swietenia Macrophylla Seed Extracts and Limonoid Compounds in Regulating Macrophage Cholesterol Homeostasis , Project Leader, 2018 to 2020, Taylor's University
- Advancing Co-creation of RLOs to Digitise healthcare curricula (ACoRD), Co-researcher, 2018 to 2022, International
Awards and Stewardship
- International University Carnival on E-Learning (IUCEL 2022), Competition, Ministry of Higher Education, Gold award , 2022
- The Virtual International e-Content Development Competition 2021, Competition, Ministry of Higher Education, Gold Award , 2021
- Outstanding Open Educational Resources (OER) Award, Competition, Ministry of Higher Education, Outstanding Open Educational Resources (OER) Award , 2021
- FAOBMB Education Special Travel Fellowship 2021, Conference, Federation of National Societies of Biochemistry and Molecular Biology (FAOBMB), Australia, Fellowship , 2021
- International e-Learning Carnival & Conference Gold Award, Conference, Ministry of Higher Education, Best Presentation , 2019
- International University Carnival on eLearning Bronze Award, Conference, Ministry of Higher Education, Best Presentation , 2018
- Putra InnoCreative Carnival in Teaching and Learning 2018 Silver Award, Conference, Universiti Putra Malaysia (UPM), Best Presentation , 2018
- Elsevier Reviewer Recognition (Biomedicine and Pharmacotherapy), Services, Elsevier, Journal Reviewer Award , 2017
- SPARK award, Competition, Taylor's University, Creativity , 2016
- International University Carnival on eLearning - Bronze award, Conference, Ministry of Higher Education, Best Presentation , 2016
Paper Presented
- ASSESSING CRITICAL THINKING USING LABORATORY DATA-GENERATORS: A CASE STUDY ON CLONING OF CRISPR CONSTRUCT, International University Carnival on E-Learning (CONFERENCE), ORAL PRESENTER , 28/06/2022 to 30/06/2022
- Fireside chat: Assessing Laboratory in an online environment: Can it be done? (Higher education: digital assessment) , Edutech Asia: Inspiring the next generation across Asia (SEMINAR), INVITED SPEAKER , 09/11/2021 to 11/11/2021
- Foam cell formation: Targeting macrophage lipids homeostasis and inflammation in atherosclerosis, Graduate Research Symposium 2021 (CONFERENCE), PLEANARY/KEYNOTE SPEAKER , 30/11/2021 to 30/11/2021
- Secretory Phospholipase A2-IIA-regulation of macrophage lipid accumulation by Maslinic acid a potent anti-inflammatory molecule, 43rd PSBMB Annual Convention (CONFERENCE), ORAL PRESENTER , 05/12/2016 to 07/12/2016