Dr Yap Wei Hsum


Academic Qualification

  • Doctor of Philosophy (Science), UNIVERSITY TUNKU ABDUL RAHAMAN, Malaysia
  • Bachelor of Science (Hons) in Biotechnology, UNIVERSITI TUNKU ABDUL RAHMAN, Malaysia
  • PGCHeTL, TAYLOR'S UNIVERSITY, Malaysia

Professional Qualification

No records found

Areas of Expertise

  • Medical And Health Sciences, Pharmacology, Molecular Pharmacology

Research Interest

  • Macrophage foam cells
  • Skin models

Publications

2020
  • Microalgae as Potential Anti-inflammatory Natural Product against Human Inflammatory Skin Diseases (ISI-Indexed), Frontiers in Pharmacology - Article in Journals
  • Maslinic acid suppresses macrophage foam cells formation: Regulation of monocyte recruitment and macrophage lipids homeostasis (ISI-Indexed), Vascular Pharmacology - Article in Journals
  • Angelicin A Furocoumarin Compound With Vast Biological Potential (ISI-Indexed), FRONTIERS IN PHARMACOLOGY - Article in Journals
  • Hyaluronic Acid-Mediated Drug Delivery System Targeting for Inflammatory Skin Diseases: A Mini Review (ISI-Indexed), FRONTIERS IN PHARMACOLOGY - Article in Journals
  • Soy fermentation by orally isolated putative probiotic Streptococcus salivarius for healthy oral (SCOPUS-Indexed), Journal of International Oral Health - Article in Journals
2019
  • Combining Understanding of Immunological Mechanisms and Genetic Variants Toward Development of Personalized Medicine for Psoriasis Patients (ISI-Indexed), Frontiers in Genetics - Article in Journals
  • An Optimized Cosmetic Screening Assay for Ultraviolet B (UVB) Protec-tive Property of Natural Products, Progress in Drug Discovery & Biomedical Science - Article in Journals
  • Formononetin: A Review of Its Anticancer Potentials and Mechanisms (ISI-Indexed), FRONTIERS IN PHARMACOLOGY - Article in Journals
  • Bioactivity evaluation of bio-hydroxyapatite derived from Spanish mackerel in composite scaffolds for bone tissue engineering (ISI-Indexed) - Article in Proceeding
  • Model of Experimentation for Photoprotective Properties of Natural Products Against Ultraviolet C (UVC) Damage: A Case Study On Rosmarinic Acid, Progress in Drug Discovery & Biomedical Science - Article in Journals
2018
  • A reliable and affordable 3D tumor spheroid model for natural product drug discovery: a case study of curcumin, Progress in Drug Discovery & Biomedical Science - Article in Journals
  • Maslinic acid suppresses macrophage foam cell formation via inhibition of LDL oxidation and cholesterol efflux (ISI-Indexed) - Article in Proceeding
  • Maslinic acid modulates secreted phospholipase A2-IIA (sPLA2-IIA)-mediated inflammatory effects in macrophage foam cells formation (ISI-Indexed), Journal of Biosciences - Article in Journals
  • Differential effects of sPLA2-GV and GX on cellular proliferation and lipid accumulation in HT29 colon cancer cells (ISI-Indexed), Molecular and Cellular Biochemistry - Article in Journals
  • Resveratrol Potential Antibacterial Agent against Foodborne Pathogens (ISI-Indexed), FRONTIERS IN PHARMACOLOGY - Article in Journals
2017
  • Oxidative Stress in Cardiovascular Diseases: Involvement of Nrf2 Antioxidant Redox Signaling in Macrophage Foam Cells Formation (ISI-Indexed), International Journal of Molecular Sciences - Article in Journals
2016
  • Inhibition of Human Group IIA-Secreted Phospholipase A2 and THP-1 Monocyte Recruitment by Maslinic Acid. Lipids (ISI-Indexed), Lipids - Article in Journals
2015
  • Mechanistic Perspectives of Maslinic Acid in Targeting Inflammation (ISI-Indexed), Biochemistry Research International - Article in Journals

Research

  • Antioxidative potential amphiphile-modified low molecular weight hyaluronic acid (LMWHA) loaded with kojic acid ester (KAE) nanoemulsion,  Co-researcher2019 to 2021, National
  • Unraveling the role of cellular senescence marker p16INK4a in atherosclerotic lesion fatty streaks foam cells formation,  Project Leader2019 to 2022, National
  • In vitro evaluation of polar and tropical microalgae extracts as anti-oxidative and de-pigmenting agents in cosmeceutical products,  Co-researcher2018 to 2020, Taylor's University
  • In silico prediction and in vitro validation of mauriporin-derived peptides as potential therapeutic anticancer agents,  Co-researcher2018 to 2019, Taylor's University
  • Preparation and characterisation of polyvinyl alcohol with natural hydroxyapatite from fish bone as biocomposite nanomaterial,  Co-researcher2018 to 2020, Taylor's University
  • Investigating the Modulatory Effects of Swietenia Macrophylla Seed Extracts and Limonoid Compounds in Regulating Macrophage Cholesterol Homeostasis ,  Project Leader2018 to 2020, Taylor's University
  • Acclimatory responses of a green algae to elevated temperatures: a proteomic and bioinformatics approach,  Co-researcher2017 to 2020, National
  • Unraveling the role of complement receptor 3 (CR3) in the clearance of malaria-infected erythrocytes,  Co-researcher2015 to 2018, National
  • A novel solution of arthritis - full biopolymer based bio-inspired tissue engineering cartilage ,  Co-researcher2015 to 2017, Taylor's University
  • Development and characterization of human fibroblast-derived matrices-based human skin equivalent as a novel in-vitro psoriatic model for drug testing,  Project Leader2015 to 2017, Taylor's University

Awards and Stewardship

  • International e-Learning Carnival & Conference Gold Award, Conference, Ministry of Higher Education, Best Presentation , 2019
  • International University Carnival on eLearning Bronze Award, Conference, Ministry of Higher Education, Best Presentation , 2018
  • Putra InnoCreative Carnival in Teaching and Learning 2018 Silver Award, Conference, Universiti Putra Malaysia (UPM), Best Presentation , 2018
  • Elsevier Reviewer Recognition (Biomedicine and Pharmacotherapy), Services, Elsevier, Journal Reviewer Award , 2017
  • SPARK award, Competition, Taylor's University, Creativity , 2016
  • International University Carnival on eLearning - Bronze award, Conference, Ministry of Higher Education, Best Presentation , 2016

Paper Presented

  • Secretory Phospholipase A2-IIA-regulation of macrophage lipid accumulation by Maslinic acid a potent anti-inflammatory molecule, 43rd PSBMB Annual Convention (CONFERENCE), ORAL PRESENTER , 05/12/2016 to 07/12/2016