Curriculum Vitae

PERSONAL DETAILS

Dr Yap Wei Hsum


ADMINISTRATIVE DUTIES
(Role),(Level),(Duration)
  • Senior Lecturer II, Faculty of Health & Medical Sciences, 17/05/2013 to present
ACADEMIC QUALIFICATION
(Qualification),(Institution)
  • Doctor of Philosophy (Science), UNIVERSITY TUNKU ABDUL RAHAMAN, Malaysia
  • Bachelor of Science (Hons) in Biotechnology, UNIVERSITI TUNKU ABDUL RAHMAN, Malaysia
  • PGCHeTL, TAYLOR'S UNIVERSITY, Malaysia
AREAS OF EXPERTISE
(Area)
  • Molecular Pharmacology
RESEARCH INTEREST
(Research Area)
  • Macrophage foam cells
  • Skin models
PUBLICATIONS
(Title of publication in APA style)
Book Chapter
2018
  • Yap, W. H. (2018). Supporting Group Learning Using Collaborative Networked Platforms. In S. Tang, & C. Lim (Eds.), Preparing the Next Generation of Teachers for 21st Century Education (pp. 144-164). Hershey, PA: IGI Global. doi:10.4018/978-1-5225-4080-9.ch009
Article in Journals
2019
  • Gunter NV, Yap BJM, Chua CLL and Yap WH (2019) Combining Understanding of Immunological Mechanisms and Genetic Variants Toward Development of Personalized Medicine for Psoriasis Patients. Front. Genet. 10:395. doi: 10.3389/fgene.2019.00395 (ISI-Indexed)
  • MahendraCK, Tan LTH, Yap WH, et al. An Optimized Cosmetic Screening Assay for Ultraviolet B (UVB) Protec-tive Property of Natural Products. Prog Drug Discov Biomed Sci 2019; 2(1): a00000xx
  • Tay K-C, Tan LT-H, Chan CK, Hong SL, Chan K-G, Yap WH, Pusparajah P, Lee L-H and Goh B-H (2019) Formononetin: A Review of Its Anticancer Potentials and Mechanisms. Front. Pharmacol. 10:820. doi: 10.3389/fphar.2019.00820 (ISI-Indexed)
2018
  • Tan LTH, Low LE, Tang SY, et al. A reliable and affordable 3D tumor spheroid model for natural product drug discovery: a case study of curcumin. Prog Drug Discov Biomed Sci 2018; 1(1): a0000017
  • Yap, W.H., Phang, S.W., Ahmed, N. et al. (2018). Differential effects of sPLA2-GV and GX on cellular proliferation and lipid accumulation in HT29 colon cancer cells, Mol Cell Biochem. pp 1–9. (ISI-Indexed)
  • Ma DSL, Tan LT-H, Chan K-G, Yap WH, Pusparajah P, Chuah L-H, Ming LC, Khan TM, Lee L-H and Goh B-H (2018) Resveratrol—Potential Antibacterial Agent against Foodborne Pathogens. Front. Pharmacol. 9:102. doi: 10.3389/fphar.2018.00102 (ISI-Indexed)
  • Yap, W.H., Ooi, B.K., Ahmed, N. et al. J Biosci (2018). Maslinic acid modulates secreted phospholipase A2-IIA (sPLA2-IIA)-mediated inflammatory effects in macrophage foam cells formation. Journal of Biosciences, pp 1-9 (ISI-Indexed)
  • Yong, L.C., Abdul Malek, N.F., Se Yong, E.N., Yap, W.H., Nobuyuki, M., Yoshitaka, N. (2018). Fabrication of Hydroxyapatite blended cyclic type Polylactic Acid and Poly (ε-Caprolactone) Tissue Engineering Scaffold, International Journal of Applied Ceramic Technology. DOI: 10.1111/ijac.13115 (ISI-Indexed)
  • Ooi BK, Chan K-G, Goh BH and Yap WH (2018) The Role of Natural Products in Targeting Cardiovascular Diseases via Nrf2 Pathway: Novel Molecular Mechanisms and Therapeutic Approaches. Front. Pharmacol. 9:1308. doi: 10.3389/fphar.2018.01308 (ISI-Indexed)
2017
  • Ooi, B.K.; Goh, B.H.; Yap, W.H. Oxidative Stress in Cardiovascular Diseases: Involvement of Nrf2 Antioxidant Redox Signaling in Macrophage Foam Cells Formation. Int. J. Mol. Sci. 2017, 18, 2336. (ISI-Indexed)
2016
  • Yap W.H., Ahmed N., Lim Y.M. (2016). Inhibition of Human Group IIA-Secreted Phospholipase A2 and THP-1 Monocyte Recruitment by Maslinic Acid. Lipids, 51(10), pp.1153-1159 (ISI-Indexed)
2015
  • Yap W.H., Lim Y.M. (2015). Mechanistic Perspectives of Maslinic Acid in Targeting Inflammation. Biochemistry Research International 2015, pp.- (ISI-Indexed)
Article in Proceeding
2018
  • Phang S, Ooi B, Ahmed N and Yap W (2019). Maslinic acid suppresses macrophage foam cell formation via inhibition of LDL oxidation and cholesterol efflux. Front. Pharmacol. Conference Abstract: International Conference on Drug Discovery and Translational Medicine 2018 (ICDDTM '18) “Seizing Opportunities and Addressing Challenges of Precision Medicine”. doi: 10.3389/conf.fphar.2018.63.00025 (ISI-Indexed)
RESEARCH PROJECT
(Project title),(Role),(Duration),(Level)
  • In vitro evaluation of polar and tropical microalgae extracts as anti-oxidative and de-pigmenting agents in cosmeceutical products, Co-researcher, 2018 to 2020 (Taylor's University)
  • Preparation and characterisation of polyvinyl alcohol with natural hydroxyapatite from fish bone as biocomposite nanomaterial, Co-researcher, 2018 to 2019 (Taylor's University)
  • In silico prediction and in vitro validation of mauriporin-derived peptides as potential therapeutic anticancer agents, Co-researcher, 2018 to 2019 (Taylor's University)
  • Acclimatory responses of a green algae to elevated temperatures: a proteomic and bioinformatics approach, Co-researcher, 2017 to 2020 (National)
  • Evaluating the mechanism of maslinic acid in monocyte recruitment and foam cell macrophage formation: Regulatory effect of NF-kB and Nrf2, Project Leader, 2015 to 2019 (National)
  • Development and characterization of human fibroblast-derived matrices-based human skin equivalent as a novel in-vitro psoriatic model for drug testing, Project Leader, 2015 to 2017 (Taylor's University)
  • A novel solution of arthritis - full biopolymer based bio-inspired tissue engineering cartilage , Co-researcher, 2015 to 2017 (Taylor's University)
  • Unraveling the role of complement receptor 3 (CR3) in the clearance of malaria-infected erythrocytes, Co-researcher, 2015 to 2018 (National)
  • Development of probiotic-fermented-soy-based orally-dissolving strip for oral health, Co-researcher, 2014 to 2017 (National)
SUPERVISION
(Title of Thesis),(Name of Candidates),(Academic Level),(Role)
COMPLETED
  • THE ROLE OF p53 IN 2-METHOXY 1,4-NAPTHOQUINONE (MNQ) INDUCED CELL CYCLE ARREST AT G2/M IN AN OSTEOSARCOMA (U-2OS) CELL LINE., CHARMAINE PATRICIA IGNATIUS  (Co-supervisor (Internal))
ONGOING
  • OOI BEE KEE  (Main Supervisor)
  • CHEAH TOH YANG  (Main Supervisor)
PRESENTATION
(Title),(Event),(Date Presented),(Organiser),(Level)
ORAL PRESENTER
  • Secretory Phospholipase A2-IIA-regulation of macrophage lipid accumulation by Maslinic acid a potent anti-inflammatory molecule, 43rd PSBMB Annual Convention, 05/12/2016 to 07/12/2016, The Philippine Society for Biochemistry and Molecular Biology (PSBMB) (International)